Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	97972
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Characteristics and risk factor analyses of high-grade intraepithelial neoplasia in older patients with colorectal polyps
Manuscript Source	Unsolicited Manuscript
All Author List	Xin Zhang, Ying Wang, Tong Zhu, Jian Ge and Jun-Hua Yuan
Funding Agency and Grant Number
Corresponding Author	Jun-Hua Yuan, Doctor, Professor, Department of Geriatric Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, No. 324 Jingwu Road, Huaiyin District, Jinan 250021, Shandong Province, China. yjh717299@126.com
Key Words	Elderly; Colorectal polyps; High-grade intraepithelial neoplasia; Low-grade intraepithelial neoplasia; Risk factors
Core Tip	Elderly patients diagnosed with colorectal polyps admitted to our hospital from January 2021 to December 2023 were included in the study. High-grade intraepithelial neoplasia characteristics and risk factors of elderly colorectal polyps were analyzed, to provide references for early screening, monitoring and treatment of colorectal polyps in the elderly. Studies have found that the occurrence of high-grade neoplasia in colorectal polyps is closely related to its location, size, villous characteristics, family history, and increased level of tumor markers. Based on these factors, it was found that the early diagnosis and treatment of patients with colorectal polyps could be made, which is of great significance to prevent high-grade neoplasia and even further malignant transformation of polyps in these patients.
Citation	Zhang X, Wang Y, Zhu T, Ge J, Yuan JH. Characteristics and risk factor analyses of high-grade intraepithelial neoplasia in older patients with colorectal polyps. World J Gastrointest Oncol 2024; In press

Received	2024-07-24 12:07
Peer-Review Started	2024-07-24 12:07
To Make the First Decision
Return for Revision	2024-08-09 10:54
Revised	2024-08-13 07:34
Second Decision	2024-09-05 02:40
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-09-05 07:48
Articles in Press	2024-09-05 07:48
Publication Fee Transferred	2024-09-06 05:09
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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