Publication Name	World Journal of Diabetes
Manuscript ID	98552
Country	China

Category	Endocrinology & Metabolism
Manuscript Type	Prospective Study
Article Title	Efficacy of sodium−glucose cotransporter-2 inhibitors and glucagon-like peptide-1 receptor agonists on proteinuria and weight in a diabetes cohort
Manuscript Source	Unsolicited Manuscript
All Author List	Di-Fei Lu, Rui Zheng, Ang Li and Jun-Qing Zhang
Funding Agency and Grant Number
Corresponding Author	Jun-Qing Zhang, MD, PhD, Department of Endocrinology, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing 100034, China. junqing.zhang@pkufh.com
Key Words	Type 2 diabetes; Chronic kidney disease; Body weight; Sodium-glucose cotransporter-2 inhibitors; Glucagon-like peptide-1 receptor agonists
Core Tip	In this study, a cohort of 5482 patients with type 2 diabetes were enrolled and followed up for at least 6 months. After propensity score matching, patients who received GLP-1RA or SGLT2i were compared with those who did not receive either treatment. Patients with increased BMIs were predisposed to treatment with GLP-1RAs, and those with higher UACRs were more likely to be treated with SGLT2is. Patients on SGLT2i or GLP-1RAs showed significant weight loss, a decreasing trend in UACR and comparable glucose-lowering effects compared with patients who received glucose-lowering drugs other than SGLT2i or GLP-1RA in real-world settings.
Citation	<p>Lu DF, Zheng R, Li A, Zhang JQ. Efficacy of sodium−glucose cotransporter-2 inhibitors and glucagon-like peptide-1 receptor agonists on proteinuria and weight in a diabetes cohort. <i>World J Diabetes</i> 2025; 16(2): 98552</p>

Received	2024-06-29 01:48
Peer-Review Started	2024-06-29 01:48
To Make the First Decision
Return for Revision	2024-09-29 13:01
Revised	2024-10-11 04:17
Second Decision	2024-10-24 02:54
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-12-02 10:27
Articles in Press	2024-12-02 10:27
Publication Fee Transferred	2024-12-02 13:00
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-12-09 02:13

ISSN	1948-9358 (online)
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