Publication Name	World Journal of Diabetes
Manuscript ID	98897
Country	China

Category	Endocrinology & Metabolism
Manuscript Type	Retrospective Study
Article Title	Correlation between diabetic peripheral neuropathy and thyroid hormone sensitivity in elderly patients with type 2 diabetes mellitus
Manuscript Source	Unsolicited Manuscript
All Author List	Si-Jia Fei, Jing-Yi Luo, Wei-Hao Wang, Li-Xin Guo and Qi Pan
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 82270881 and 82200928 National High-Level Hospital Clinical Research Funding BJ-2023-124 and BJ-2023-130
Corresponding Author	Qi Pan, PhD, Department of Endocrinology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, No. 1 Dahua Road, Dongcheng District, Beijing 100730, China. panqi621@126.com
Key Words	Diabetic peripheral neuropathy; Thyroid hormone sensitivity; Type 2 diabetes mellitus; Elderly; Free triiodothyronine/free thyroxine ratio
Core Tip	In this study, we explore the relationship between thyroid hormone sensitivity and diabetic peripheral neuropathy (DPN) in elderly patients with type 2 diabetes mellitus (T2DM). Our findings indicate that a lower free triiodothyronine/free thyroxine (FT3/FT4) ratio is significantly associated with increased DPN incidence, affecting both large and small nerve fibers. The FT3/FT4 ratio serves as an effective predictor for DPN, enhancing diagnostic accuracy. These results highlight the importance of assessing thyroid hormone sensitivity in managing and predicting DPN in elderly patients with T2DM, offering new insights into the pathophysiological mechanisms underlying this complication.
Citation	Fei SJ, Luo JY, Wang WH, Guo LX, Pan Q. Correlation between diabetic peripheral neuropathy and thyroid hormone sensitivity in elderly patients with type 2 diabetes mellitus. World J Diabetes 2024; In press

Received	2024-07-31 02:11
Peer-Review Started	2024-07-10 04:50
To Make the First Decision
Return for Revision	2024-10-11 03:26
Revised	2024-10-23 17:55
Second Decision	2024-11-18 04:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-11-26 07:40
Articles in Press	2024-11-26 07:40
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9358 (online)
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