Publication Name	World Journal of Radiology
Manuscript ID	99007
Country	China

Category	Oncology
Manuscript Type	Case Report
Article Title	Pneumocystis pneumonia in stage IIIA lung adenocarcinoma with immune-related acute kidney injury and thoracic radiotherapy: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Ya-Wen Zheng, Jia-Chao Pan, Jin-Feng Wang and Jian Zhang
Funding Agency and Grant Number	Funding Agency Grant Number Shandong Natural Science Foundation ZR2021QH034 China Postdoctoral Science Foundation 2023M731305
Corresponding Author	Ya-Wen Zheng, MD, PhD, Associate Chief Physician, Department of Oncology, Central Hospital Affiliated to Shandong First Medical University, No. 105 Jiefang Road, Jinan 250000, Shandong Province, China. zyawen06@126.com
Key Words	Pneumocystis pneumonia; Immune related adverse events; Immunotherapy; Thoracic radiotherapy; Acute kidney injury; Case report
Core Tip	A patient with squamous lung cancer was treated with triplimab combined with paclitaxel, carboplatin, and radical thoracic radiation therapy. Despite the good therapeutic effect, he developed a grade 3 immune-related acute kidney injury, prompting high-dose corticosteroids treatment. Eight weeks later, the patient developed severe pneumonia with spontaneous pneumothorax, and was diagnosed with Pneumocystis jirovecii pneumonia (PJP) co-infection with the herpes simplex virus 1 and cytomegalovirus. PJP is rare but might occur in patients with immune checkpoint inhibitor adverse events, highlighting the need to be differentiated from tumor progression or immune-related adverse events.
Citation	Zheng YW, Pan JC, Wang JF, Zhang J. Pneumocystis pneumonia in stage IIIA lung adenocarcinoma with immune-related acute kidney injury and thoracic radiotherapy: A case report. World J Radiol 2024; In press

Received	2024-07-11 14:16
Peer-Review Started	2024-07-11 14:16
To Make the First Decision
Return for Revision	2024-08-05 05:50
Revised	2024-08-16 15:33
Second Decision	2024-09-03 02:45
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-09-03 11:10
Articles in Press	2024-09-03 11:10
Publication Fee Transferred	2024-09-04 00:42
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1949-8470 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com