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Articles in Press
11/26/2024 8:05:48 AM | Browse: 38 | Download: 23
Category |
Medicine, Research & Experimental |
Manuscript Type |
Basic Study |
Article Title |
Plantamajoside improves type 2 diabetes mellitus pancreatic β-cell damage by inhibiting endoplasmic reticulum stress through Dnajc1 up-regulation
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Duo Wang, Yuan-Song Wang, Hong-Min Zhao, Peng Lu, Meng Li, Wei Li, Huan-Tian Cui, Zhong-Yong Zhang and Shu-Quan Lv |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Yuansong Wang National Famous Traditional Chinese Medicine Expert Heritage Studio |
4 (2022) |
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Corresponding Author |
Zhong-Yong Zhang, Department of Endocrinology, Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine of Hebei Province Affiliated to Hebei University of Chinese Medicine, Cangzhou 061000, Hebei Province, China. zzyhappy666@126.com |
Key Words |
Type 2 diabetes mellitus; Plantamajoside; Transcriptomics; Islet beta cell injury; MIN6 cell; Endoplasmic reticulum stress; Dnajc1 |
Core Tip |
Plantamajoside (PMS) exhibits therapeutic effects in rats with type 2 diabetes mellitus pancreatic β-cell damage. The mechanism of action of PMS appears to involve the activation of Dnajc1, which subsequently inhibits apoptosis and endoplasmic reticulum stress, ultimately ameliorating damage to pancreatic β-cells. |
Citation |
Wang D, Wang YS, Zhao HM, Lu P, Li M, Li W, Cui HT, Zhang ZY, Lv SQ. Plantamajoside improves type 2 diabetes mellitus pancreatic β-cell damage by inhibiting endoplasmic reticulum stress through Dnajc1 up-regulation. World J Diabetes 2024; In press |
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Received |
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2024-07-12 04:22 |
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Peer-Review Started |
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2024-07-12 04:22 |
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To Make the First Decision |
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Return for Revision |
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2024-10-14 06:19 |
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Revised |
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2024-10-26 15:35 |
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Second Decision |
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2024-11-13 03:16 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-11-26 08:05 |
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Articles in Press |
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2024-11-26 08:05 |
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Publication Fee Transferred |
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2024-12-01 12:41 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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ISSN |
1948-9358 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
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