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11/26/2024 8:05:48 AM | Browse: 38 | Download: 23
Publication Name World Journal of Diabetes
Manuscript ID 99053
Country China
Category Medicine, Research & Experimental
Manuscript Type Basic Study
Article Title Plantamajoside improves type 2 diabetes mellitus pancreatic β-cell damage by inhibiting endoplasmic reticulum stress through Dnajc1 up-regulation
Manuscript Source Unsolicited Manuscript
All Author List Duo Wang, Yuan-Song Wang, Hong-Min Zhao, Peng Lu, Meng Li, Wei Li, Huan-Tian Cui, Zhong-Yong Zhang and Shu-Quan Lv
Funding Agency and Grant Number
Funding Agency Grant Number
Yuansong Wang National Famous Traditional Chinese Medicine Expert Heritage Studio 4 (2022)
Corresponding Author Zhong-Yong Zhang, Department of Endocrinology, Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine of Hebei Province Affiliated to Hebei University of Chinese Medicine, Cangzhou 061000, Hebei Province, China. zzyhappy666@126.com
Key Words Type 2 diabetes mellitus; Plantamajoside; Transcriptomics; Islet beta cell injury; MIN6 cell; Endoplasmic reticulum stress; Dnajc1
Core Tip Plantamajoside (PMS) exhibits therapeutic effects in rats with type 2 diabetes mellitus pancreatic β-cell damage. The mechanism of action of PMS appears to involve the activation of Dnajc1, which subsequently inhibits apoptosis and endoplasmic reticulum stress, ultimately ameliorating damage to pancreatic β-cells.
Citation Wang D, Wang YS, Zhao HM, Lu P, Li M, Li W, Cui HT, Zhang ZY, Lv SQ. Plantamajoside improves type 2 diabetes mellitus pancreatic β-cell damage by inhibiting endoplasmic reticulum stress through Dnajc1 up-regulation. World J Diabetes 2024; In press
Received
2024-07-12 04:22
Peer-Review Started
2024-07-12 04:22
To Make the First Decision
Return for Revision
2024-10-14 06:19
Revised
2024-10-26 15:35
Second Decision
2024-11-13 03:16
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2024-11-26 08:05
Articles in Press
2024-11-26 08:05
Publication Fee Transferred
2024-12-01 12:41
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
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