Publication Name	World Journal of Critical Care Medicine
Manuscript ID	99445
Country	United States

Category	Critical Care Medicine
Manuscript Type	Meta-Analysis
Article Title	Association between neutrophil-to-lymphocyte ratio and hematoma expansion in spontaneous intracerebral hemorrhage: A systematic review and meta-analysis
Manuscript Source	Invited Manuscript
All Author List	Andrea Loggini, Jonatan Hornik, Jessie Henson, Julie Wesler and Alejandro Hornik
Funding Agency and Grant Number
Corresponding Author	Andrea Loggini, MD, Brain and Spine Institute, Southern Illinois Healthcare, 405 W Jackson Street, Carbondale, IL 62901, United States. andrea.loggini@sih.net
Key Words	Neutrophil-to-lymphocyte ratio; Hematoma expansion; Perihematomal growth; Intracerebral hemorrhage; Hemorrhagic stroke
Core Tip	In this work, we provide an updated and concise quantitative synthesis of the literature addressing the association between neutrophil-to-lymphocyte ratio and hematoma expansion (HE) in intracerebral hemorrhage. We found an independent association between neutrophil-to-lymphocyte ratio (NLR) on admission and HE, and perihematomal growth. Our findings support the idea that NLR could be added as a readily available and inexpensive biomarker to identify a subgroup of patients at higher risk of developing HE.
Citation	<p>Loggini A, Hornik J, Henson J, Wesler J, Hornik A. Association between neutrophil-to-lymphocyte ratio and hematoma expansion in spontaneous intracerebral hemorrhage: A systematic review and meta-analysis. <i>World J Crit Care Med</i> 2025; 14(2): 99445</p>

Received	2024-07-22 20:51
Peer-Review Started	2024-07-22 20:51
To Make the First Decision
Return for Revision	2024-11-26 08:40
Revised	2024-12-02 17:47
Second Decision	2024-12-16 02:51
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-12-16 07:28
Articles in Press	2024-12-16 07:28
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-12-30 04:15

ISSN	2220-3141(online)
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