Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	99474
Country	China

Category	Oncology
Manuscript Type	Basic Study
Article Title	Effects of invigorating-spleen and anticancer prescription on extracellular signal-regulated kinase/mitogen-activated protein kinase signaling pathway in colon cancer mice model
Manuscript Source	Unsolicited Manuscript
All Author List	Wei Wang, Jing Wang, Xiu-Xiu Ren, Hai-Long Yue and Zheng Li
Funding Agency and Grant Number	Funding Agency Grant Number Liaoning Provincial Science and Technology Department Project 2023JH2/101700149 Open Fund Project of Liaoning University of Traditional Chinese Medicine zyzx2205
Corresponding Author	Zheng Li, MD, Chief Physician, Department of Integrated Traditional Chinese and Western Medicine Medical Oncology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, No. 44 Xiaoheyan Road, Dadong District, Shenyang 110042, Liaoning Province, China. fox_dl1984@163.com
Key Words	Colon cancer; Invigorating-spleen and anticancer formula; Extracellular signal-regulated kinase/mitogen-activated protein kinase signaling pathway; Mice model; C-MYC
Core Tip	The incidence and mortality of intestinal cancer is increasing year by year. Due to the limited therapeutic means and low survival rate of advanced patients, and the easy development of drug resistance to chemotherapy, targeting and immunotherapy, we have found that spleen-healthy anticancer formula can play an anti-tumor role through the extracellular-signal-regulated kinase/mitogen-activated protein kinase signaling pathway and inhibit the expression of matrix metalloproteinase 2 and c-myc.
Citation	Wang W, Wang J, Ren XX, Yue HL, Li Z. Effects of invigorating-spleen and anticancer prescription on extracellular signal-regulated kinase/mitogen-activated protein kinase signaling pathway in colon cancer mice model. World J Gastrointest Oncol 2024; In press

Received	2024-08-06 08:35
Peer-Review Started	2024-08-06 08:35
To Make the First Decision
Return for Revision	2024-08-26 10:17
Revised	2024-09-06 11:46
Second Decision	2024-09-29 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-09-29 07:55
Articles in Press	2024-09-29 07:55
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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