Publication Name	World Journal of Virology
Manuscript ID	99663
Country	India

Category	Critical Care Medicine
Manuscript Type	Observational Study
Article Title	Risk of COVID-19 infection among frontline healthcare workers during the COVID-19 pandemic
Manuscript Source	Invited Manuscript
All Author List	Kundavaram Paul Prabhakar Abhilash, Mathew Varghese Nellimootil, Binila Chacko, Darpanarayan Hazra, Victor Coelho, John Emmanuel Jesudasan, Karthik Gunasekaran, Lovely Thomas, More Atul Ramchandra, Jonathan Melchizedek, Henah Meshack Gunaraj, Mahesh Moorthy and John Victor Peter
Funding Agency and Grant Number	Funding Agency Grant Number Internal Institutional Research Fund
Corresponding Author	John Victor Peter, MD, Professor, Department of Medical Intensive Care, Christian Medical College Vellore, Ida Scudder Road, Vellore 632004, Tamil Nādu, India. peterjohnvictor@yahoo.com.au
Key Words	COVID-19 pandemic; Seroprevalence; Healthcare workers; SARS-CoV-2 antibodies; Nucleocapsid antibody; Spike protein antibody
Core Tip	This study tracked clinical infection and seroprevalence to severe acute respiratory syndrome-coronavirus 2 virus during the two waves of the pandemic in India and compared infection risk between health care workers (HCWs) in high-risk (HR) areas (emergency department, critical care) and low-risk (LR) non-clinical areas. The seroprevalence rate of 1.1% at the start of the pandemic increased to 34.1% and 60.1% during the first and second waves respectively. Prior to vaccination, more HCWs in HR areas developed clinical infection. Following vaccination, clinical infection rates and seropositivity were similar in HR and LR groups. About 1/3rd had evidence of subclinical infection.
Citation	Abhilash KPP, Nellimootil MV, Chacko B, Hazra D, Coelho V, Jesudasan JE, Gunasekaran K, Thomas L, Ramchandra MA, Melchizedek J, Gunaraj HM, Moorthy M, Peter JV. Risk of COVID-19 infection among frontline healthcare workers during the COVID-19 pandemic. World J Virol 2025; In press

Received	2024-07-27 06:15
Peer-Review Started	2024-07-27 06:15
To Make the First Decision
Return for Revision	2024-10-25 03:32
Revised	2024-11-07 10:04
Second Decision	2024-11-26 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-11-26 09:06
Articles in Press	2024-11-26 09:06
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ISSN	2220-3249 (online)
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