Publication Name	World Journal of Gastroenterology
Manuscript ID	99684
Country	China

Category	Endocrinology & Metabolism
Manuscript Type	Editorial
Article Title	Glucagon-like peptide-1 receptor agonists: Exploring the mechanisms from glycemic control to treatment of multisystemic diseases
Manuscript Source	Invited Manuscript
All Author List	Mo-Wei Kong, Yang Yu, Ying Wan, Yu Gao and Chun-Xiang Zhang
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China U23A20398 National Natural Science Foundation of China 82030007 Sichuan Science and Technology Program 2022YFS0578
Corresponding Author	Chun-Xiang Zhang, MD, Dean, Professor, Department of Cardiology, The Affiliated Hospital of Southwest Medical University, No. 1735 West Harrison Street, Luzhou 646000, Sichuan Province, China. zhangchx999@163.com
Key Words	Glucagon-like peptide-1 receptor agonists; Glycemic control; Multisystem diseases; Mechanism of action; Cardiovascular protection; Renal disease; Bone metabolism; Non-alcoholic fatty liver disease; Neuroprotection; Polycystic ovary syndrome
Core Tip	This editorial serves as an extension to the insightful research by Soresi and Giannitrapani, initially presented in the World Journal of Gastroenterology. We revisit their focus on the role of glucagon-like peptide-1 receptor agonists (GLP-1RAs) in treating metabolic dysfunction-associated fatty liver disease, and supplement their work by exploring the broader systemic applications of GLP-1RAs. Our aim is to provide a comprehensive overview of the mechanisms of action of GLP-1RAs and to highlight the latest research developments, emphasizing their potential in managing a variety of diseases. We emphasize the multifaceted therapeutic value of GLP-1RAs and encourage further investigation into their clinical utility across different medical specialties.
Citation	Kong MW, Yu Y, Wan Y, Gao Y, Zhang C. Glucagon-like peptide-1 receptor agonists: Exploring the mechanisms from glycemic control to treatment of multisystemic diseases. World J Gastroenterol 2024; In press

Received	2024-07-27 19:52
Peer-Review Started	2024-07-27 19:52
To Make the First Decision
Return for Revision	2024-08-05 20:21
Revised	2024-08-08 04:57
Second Decision	2024-09-05 02:40
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-09-05 06:20
Articles in Press	2024-09-05 06:20
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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