Publication Name	World Journal of Hepatology
Manuscript ID	99809
Country	Brazil

Category	Gastroenterology & Hepatology
Manuscript Type	Opinion Review
Article Title	Which patients benefit the most? An update on transjugular intrahepatic portosystemic shunt
Manuscript Source	Invited Manuscript
All Author List	Angelo Alves de Mattos, Angelo Zambam de Mattos, Muriel Manica and Cristiane Valle Tovo
Funding Agency and Grant Number
Corresponding Author	Cristiane Valle Tovo, MD, PhD, Postgraduation Program in Medicine: Hepatology, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Rua Sarmento Leite 245, Porto Alegre 90050-170, Rio Grande do Sul, Brazil. cristianev@ufcspa.edu.br
Key Words	Transjugular intrahepatic portosystemic shunt; Refractory ascites; Variceal bleeding; Portal hypertension; Hepatic encephalopathy
Core Tip	This is a narrative review where the advances in technical aspects, the main indications, limitations and clinical results of the transjugular intrahepatic portosystemic shunt (TIPS) in portal hypertension (PH) are addressed. With the coated prosthesis, a better shunt patency, a lower incidence of hepatic encephalopathy and better survival when compared to the not covered prosthesis are demonstrated. The main indications for TIPS are refractory ascites, acute variceal bleeding unresponsive to pharmacological/endoscopic therapy and, lastly, patients considered at high risk for rebleeding preemptive TIPS. In conclusion, TIPS is an essential treatment for patients with PH, but is often neglected.
Citation	Mattos AA, Mattos AZ, Tovo CV, Manica M. Which patients benefit the most? An update on transjugular intrahepatic portosystemic shunt. World J Hepatol 2025; In press

Received	2024-08-22 06:15
Peer-Review Started	2024-07-31 11:38
To Make the First Decision
Return for Revision	2024-12-18 11:14
Revised	2024-12-23 21:48
Second Decision	2025-01-09 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-01-09 08:51
Articles in Press	2025-01-09 08:51
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Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
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