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1
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"Small sample size is a fatal defect."
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Li XP, Bao ZT, Wang L, Zhang CY, Yang W. Construction of a predictive model for acute liver failure after hepatectomy based on neutrophil-to-lymphocyte ratio and albumin-bilirubin score. World J Gastrointest Surg 2024; 16(4): 1087-1096 [DOI: 10.4240/wjgs.v16.i4.1087]
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2
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"The article is very clear and addresses the topic comprehensively"
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Bhogal S, Batta A. Transcatheter aortic valve replacement in low-risk young population: A double edge sword? World J Cardiol 2024; 16(4): 177-180 [DOI: 10.4330/wjc.v16.i4.177]
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3
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"It is a well-arranged editorial."
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Pesce A, Fabbri N, Iovino D, Feo CV. Parallel pathways: A chronicle of evolution in rectal and breast cancer surgery. World J Gastrointest Oncol 2024; 16(4): 1091-1096 [PMID: 38660632 DOI: 10.4251/wjgo.v16.i4.1091]
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4
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"None"
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Metelkina-Fernandez V, Dumas LE, Vandersteen C, Chirio D, Gros A, Fernandez A, Askenazy F, Manera V. Psychiatric outcomes in outpatients affected by long COVID: A link between mental health and persistence of olfactory complaint. World J Psychiatry 2024; 14(4): 507-512 [PMID: 38659602 DOI: 10.5498/wjp.v14.i4.507]
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5
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"Small sample recruited through purposive sampling can be a major bias in this study."
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Xin Y, Lin FC, Huang C, He B, Yan YL, Wang S, Zhang GM, Li R. Nurse anesthetists’ perceptions and experiences of managing emergence delirium: A qualitative study. World J Psychiatry 2024; 14(4): 553-562 [PMID: 38659604 DOI: 10.5498/wjp.v14.i4.553]
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6
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"None"
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Liu XQ, Wang X. Adolescent suicide risk factors and the integration of social-emotional skills in school-based prevention programs. World J Psychiatry 2024; 14(4): 494-506 [PMID: 38659598 DOI: 10.5498/wjp.v14.i4.494]
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7
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"This review introduces in detail the epidemiology of rectal cancer, the application and development of AI in diagnosis, prediction, treatment and evaluation of rectal cancer. The research of AI and machine learning in rectal cancer is reviewed and discussed. The article also summarized the liminations of AI in rectal cancer, such as AI in surgical decision-making is very limited."
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Yadav A, Kumar A. Artificial intelligence in rectal cancer: What is the future? Artif Intell Cancer 2023; 4(2): 11-22 [DOI: 10.35713/aic.v4.i2.11]
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8
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"This is very interesting paper. Please explain the cause and treatment for osteosarcopenia and myosteotosis when it comes to HCC."
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Jadzic J, Djonic D. Hepatocellular carcinoma and musculoskeletal system: A narrative literature review. World J Gastroenterol 2024; 30(15): 2109-2117 [DOI: 10.3748/wjg.v30.i15.2109]
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9
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"Overall, the paper utilized three different animal models to presents an interesting analysis of differentially expressed genes associated with the progression of AP. The authors have utilized appropriate experimental methods and statistical approaches to identify a number of candidate genes that may play a role in the disease process. This is a valuable contribution to the field."
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Zheng P, Li XY, Yang XY, Wang H, Ding L, He C, Wan JH, Ke HJ, Lu NH, Li NS, Zhu Y. Comparative transcriptomic analysis reveals the molecular changes of acute pancreatitis in experimental models. World J Gastroenterol 2024; 30(14): 2038-2058 [DOI: 10.3748/wjg.v30.i14.2038]
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10
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"This study found that the factors of neuroplasticity and cellular/vascular changes in female adult offspring born from mothers treated with STZ can control some long-term metabolic complications of GDM in adult offspring, providing valuable pharmacological solutions and expanding our understanding of gestational diabetes. The understanding of the disease state of mouse offspring is a valuable study."
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Muñoz-Islas E, Santiago-SanMartin ED, Mendoza-Sánchez E, Torres-Rodríguez HF, Ramírez-Quintanilla LY, Peters CM, Jiménez-Andrade JM. Long-term effects of gestational diabetes mellitus on the pancreas of female mouse offspring. World J Diabetes 2024; 15(4): 758-768 [DOI: 10.4239/wjd.v15.i4.758]
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11
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"This review puts forward the connection between Nε-carboxymethyllysine as the main final inflammatory factor and diabetic coronary artery disease, which provides a new idea for the study of diabetic coronary artery disease. The content is relatively brief and requires further research."
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Eiras S. Nε-carboxymethyl-lysine and inflammatory cytokines, markers and mediators of coronary artery disease progression in diabetes. World J Diabetes 2024; 15(4): 575-578 [DOI: 10.4239/wjd.v15.i4.575]
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12
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"This review summarizes the drug selection for the treatment of diabetes in adolescents and children, and provides a meaningful reference value for clinical drug selection for this patient population. We look forward to further research to clarify the most optimal drug for adolescents and children with diabetes."
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Krnic N, Sesa V, Mrzljak A, Berkovic MC. Are treatment options used for adult-onset type 2 diabetes mellitus (equally) available and effective for children and adolescents? World J Diabetes 2024; 15(4): 623-628 [DOI: 10.4239/wjd.v15.i4.623]
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13
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"This review discusses the feasibility of weight loss treatment for obese patients with diabetes and provides a new way to treat obese patients with diabetes. It is a very meaningful article. It is expected that the content will require further detailed research."
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Tang HH, Wang D, Tang CC. Effect of bariatric surgery on metabolism in diabetes and obesity comorbidity: Insight from recent research. World J Diabetes 2024; 15(4): 586-590 [DOI: 10.4239/wjd.v15.i4.586]
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14
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"1. Was the màss palpable on examination?
2. What about the other investigations such as US / X-ray abdomen?
3. Is the follow up period adequate in this case ? What would be the ideal / recommended follow up protocol?"
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Hou TY, Tzeng WJ, Lee PH. Small intestine angioleiomyoma as a rare cause of perforation: A case report. World J Clin Cases 2024; 12(12): 2116-2121 [DOI: 10.12998/wjcc.v12.i12.2116]
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15
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"1. How to suspect a similar case in future would be a good learning tip
2. Algorithm to illustrate the management can be helpful
3. Review of literature can be more elaborate"
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Zhang N, Sun DK, Tian X, Zheng XY, Liu T. Protein C deficiency with venous and arterial thromboembolic events. World J Clin Cases 2024; 12(12): 2000-2003 [DOI: 10.12998/wjcc.v12.i12.2000]
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16
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"1. The other AI models of relevance to Liver imaging can be included
2. Note on deep learning & training of residents would be informative"
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Calleja R, Durán M, Ayllón MD, Ciria R, Briceño J. Machine learning in liver surgery: Benefits and pitfalls. World J Clin Cases 2024; 12(12): 2134-2137 [DOI: 10.12998/wjcc.v12.i12.2134]
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17
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"Albumin bilirubin’s score is a good parameter for postoperative liver status. Simple is good parameter compared to
Conventional liver function parameter."
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Takahashi K, Gosho M, Miyazaki Y, Nakahashi H, Shimomura O, Furuya K, Doi M, Owada Y, Ogawa K, Ohara Y, Akashi Y, Enomoto T, Hashimoto S, Oda T. Preoperative albumin-bilirubin score and liver resection percentage determine postoperative liver regeneration after partial hepatectomy. World J Gastroenterol 2024; 30(14): 2006-2017 [DOI: 10.3748/wjg.v30.i14.2006]
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18
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"1. A note on the potential anatomical variants with illustration would add more value to the manuscript
2.. How to suspect / pre empt the same would help in future management
3.. The conclusion may be suitably modified as a crisp take home message"
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Hu CD, Lv R, Zhao YX, Zhang MH, Zeng HD, Mao YW. Basilic vein variation encountered during surgery for arm vein port: A case report. World J Clin Cases 2024; 12(12): 2086-2091 [DOI: 10.12998/wjcc.v12.i12.2086]
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19
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"1.stepwise analgesic management with escalation related to symptoms & severity would add easy / clear understanding
2. Use of US guided blocks with dosage of medication can be included
3. Surgical drainage / coring procedures also play a vital role in management of chronic pancreatitis"
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Nag DS, Swain BP, Anand R, Barman TK, Vatsala. Pain management in chronic pancreatitis. World J Clin Cases 2024; 12(12): 2016-2022 [DOI: 10.12998/wjcc.v12.i12.2016]
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20
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"Dear Author,
One important issue in Lean body MASLD is identifying the genes involved in the pathogenesis of disease. These genes include the ones regulating lipid metabolism in liver. Sarcopenia is a very important factor in both lean and obese MASLD. The role of sarcopenia in lean body MASLD should be further studied."
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Sato-Espinoza K, Chotiprasidhi P, Huaman MR, Díaz-Ferrer J. Update in lean metabolic dysfunction-associated steatotic liver disease. World J Hepatol 2024; 16(3): 452-464 [PMID: 38577539 DOI: 10.4254/wjh.v16.i3.452]
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21
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"Dear Author
I recommend to consider the risk factors for amebic liver abscess including:
Recent travel to a tropical region.
Alcoholism.
Cancer.
Immunosuppression, including HIV/AIDS infection.
Malnutrition.
Old age.
Pregnancy.
Steroid use."
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Kumar R, Patel R, Priyadarshi RN, Narayan R, Maji T, Anand U, Soni JR. Amebic liver abscess: An update. World J Hepatol 2024; 16(3): 316-330 [PMID: 38577528 DOI: 10.4254/wjh.v16.i3.316]
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22
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"Dear Authors,
The future studies should be performed to identify precise risk factors for HDV infection. The current evidence has not yet showed the cost-effectiveness of double reflex testing strategy in all HBV positive patients.
"
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Abbas Z, Abbas M. Is there a need for universal double reflex testing of HBsAg-positive individuals for hepatitis D infection? World J Hepatol 2024; 16(3): 300-303 [PMID: 38577532 DOI: 10.4254/wjh.v16.i3.300]
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23
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"During the last few years, the study of the interaction between the gut microbiome and colorectal cancer development has revealed significant differences between colorectal cancer patients and healthy individuals in terms of gut microbiota composition and proportion of microbes. Moreover, the response of individual colorectal cancer patients to chemo- and immunotherapy also depends on the composition of the gut microbiome.
In the present study, the authors investigated the possible effect of Fusobacterium nucleatum (F. nucleatum) on the progression of colorectal cancer. They found that this bacterium suppresses butyric acid production and that sodium butyrate impairs mitochondrial function and interferes with the cell cycle in cancer cells. It was also shown that sodium butyrate and F. nucleatum orchestrate cancer cell proliferation through the adenosine monophosphate-activated protein kinase signaling pathway.
Therefore, this study contributes to our understanding of the many complex pathogenetic mechanisms of colorectal cancer, at least in part.
As for the future, such and similar studies are expected to enhance the development of more effective treatment strategies."
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Wu QL, Fang XT, Wan XX, Ding QY, Zhang YJ, Ji L, Lou YL, Li X. Fusobacterium nucleatum-induced imbalance in microbiome-derived butyric acid levels promotes the occurrence and development of colorectal cancer. World J Gastroenterol 2024; 30(14): 2018-2037 [DOI: 10.3748/wjg.v30.i14.2018]
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24
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"In this review article, the authors summarize the utility of texture and color enhancement imaging in clinical settings. However, they do not provide a description of the technological foundations. Merely listing detection rates and accuracy in comparison to white light imaging or other image-enhancing endoscopic techniques does not convincingly demonstrate the superiority of texture and color enhancement imaging. This is because detection rates and accuracy in endoscopic studies are significantly influenced not only by the differences in instrumentation but also by the skill of the observers and the pathophysiological conditions of the subjects. A lack of robust discussion fails to outline future directions. Unfortunately, this makes it a rudimentary review article."
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Toyoshima O, Nishizawa T, Hata K. Topic highlight on texture and color enhancement imaging in gastrointestinal diseases. World J Gastroenterol 2024; 30(14): 1934-1940 [DOI: 10.3748/wjg.v30.i14.1934]
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25
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"Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied."
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Milickovic M, Rasic P, Cvejic S, Bozic D, Savic D, Mijovic T, Cvetinovic S, Djuricic SM. Splenic hamartomas in children. World J Clin Cases 2024; 12(11): 1909-1917 [PMID: 38660549 DOI: 10.12998/wjcc.v12.i11.1909]
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26
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"Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied."
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Zhou PF, Lu JG, Zhang JD, Wang JW. Colonoscopy-assisted removal of an impaction foreign body at the rectosigmoid junction: A case report. World J Clin Cases 2024; 12(11): 1990-1995 [PMID: 38660553 DOI: 10.12998/wjcc.v12.i11.1990]
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27
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"Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied."
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Jagirdhar GSK, Bains Y, Surani S. Removal of intrahepatic bile duct stone could reduce the risk of cholangiocarcinoma. World J Clin Cases 2024; 12(11): 1881-1884 [PMID: 38660555 DOI: 10.12998/wjcc.v12.i11.1881]
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28
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"An excellent review article. Textbook quality in every segment.
Why is it in a Journal of Case reports ?"
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Wang TF, Chen Q, Deng J, Li SL, Xu Y, Ma SX. Research progress on venous thrombosis development in patients with malignant tumors. World J Clin Cases 2024; 12(11): 1900-1908 [PMID: 38660542 DOI: 10.12998/wjcc.v12.i11.1900]
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29
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"The manuscript is well-written, concise, without spelling or grammar errors and offers important scientific data regarding this new and promising therapeutic target for patients with ulcerative colitis in a complex but concise manner, using updated references."
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Hassan SA, Kapur N, Sheikh F, Fahad A, Jamal S. Disease clearance in ulcerative colitis: A new therapeutic target for the future. World J Gastroenterol 2024; 30(13): 1801-1809 [PMID: 38659483 DOI: 10.3748/wjg.v30.i13.1801]
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30
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"In this review article, the authors provide a narrative summary of both the basic and clinical history of researches for chronic gastritis. I maintain that a scientific article should propose hypotheses and/or strategies, grounded in either original research or meta-analysis, to establish novel evidence and perspectives that indicate future directions. Regrettably, this article resembles a history book more than a scientific manuscript. Such an article ought to be published not as an original or review piece but rather as nonfiction literature."
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Bordin D, Livzan M. History of chronic gastritis: How our perceptions have changed. World J Gastroenterol 2024; 30(13): 1851-1858 [PMID: 38659477 DOI: 10.3748/wjg.v30.i13.1851]
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31
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"In this review manuscript, the authors attempt to propose a comprehensive application of multimodal ultrasound techniques, including B-mode, Doppler, contrast enhancement, elastography, among others. However, the manuscript is marred by redundant sentences. A practical methodology is presented exclusively for assessing liver stiffness. Furthermore, while liver stiffness assessment takes into account not just fibrous accumulation but also factors such as cholestasis and congestion—as the authors mention—they fail to discuss or suggest methods to mitigate these confounding factors. Regrettably, this article falls short of achieving the objectives the authors set out for this review."
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Peltec A, Sporea I. Multiparametric ultrasound as a new concept of assessment of liver tissue damage. World J Gastroenterol 2024; 30(12): 1663-1669 [PMID: 38617743 DOI: 10.3748/wjg.v30.i12.1663]
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32
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"Thrombus formation occurred in the portal vein of intrahepatic stones in Japan due to the spread of cholangitis, and thrombus formation occurred frequently at the bifurcation, and the third and fourth branches of the portal vein, which were approximately 0.5 mm in diameter, were severely stenotic due to thrombosis. There was severe atrophy in the liver parenchyma associated with decreased portal blood flow. In other words, bile duct dilatation occurs in the long axis direction as well as in the direction of increasing diameter, and on the other hand, the contraction force of the tissue is also applied to the bile duct, so the bile duct is bent and squeezed and takes on a highly deformed shape. Based on these results, there have been reports of severe deformity of the bile ducts, portal vein stenosis, and intrahepatic lesions accompanied by hepatic parenchymal atrophy, and we would like to request consideration of liver atrophy and portal vein lesions in your paper."
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Motta RV, Saffioti F, Mavroeidis VK. Hepatolithiasis: Epidemiology, presentation, classification and management of a complex disease. World J Gastroenterol 2024; 30(13): 1836-1850 [PMID: 38659478 DOI: 10.3748/wjg.v30.i13.1836]
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33
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"How to identify and intervene early to reduce the mortality of end-stage liver disease is one of the difficulties in clinical treatment. NLR is a simple index, and it has predictive value for the prognosis of a variety of diseases. The present study conducted a large-scale meta-analysis suggesting that high levels of NLR are associated with poor prognosis in ESLD. Interestingly, this finding was more pronounced in Asian populations. Considering the different etiologies of ESLD in different regions, the authors can further explore the predictive value of NLR for prognosis under different etiologies, which will be of more clinical value."
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Cai XH, Tang YM, Chen SR, Pang JH, Chong YT, Cao H, Li XH. Prognostic value of neutrophil-to-lymphocyte ratio in end-stage liver disease: A meta-analysis. World J Hepatol 2024; 16(3): 477-489 [PMID: 38577540 DOI: 10.4254/wjh.v16.i3.477]
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34
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"Thank you for the opportunity to review the quality of this manuscript. Please see my comments below.
1 Ethics: NA given manuscript type
2 Methods: NA given manuscript type
3 Results: NA given manuscript type
4 Figures and tables: NA - no figures/tables included
5 Biostatistics: NA given manuscript type
6 References: Appropriate references included
7 Language: This is a succint and well written editorial
8 Caveats or drawbacks: None"
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Yu YB. Risk factors for lymph node metastasis in superficial esophageal squamous cell carcinoma. World J Gastroenterol 2024; 30(13): 1810-1814 [PMID: 38659479 DOI: 10.3748/wjg.v30.i13.1810]
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35
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"The authors of this study showed that serum levels of GDF-15 in IBD patients are elevated compared to normal controls regardless of factors affecting the normal serum levels of this factor. The authors found a significant correlation with the endoscopic severity and other parameters of both ulcerative colitis and Crohn's disease. GDF-15 is weakly overexpressed under normal conditions, but its secretion increases in stressful situations. The authors hypothesize that this factor may be involved in the pathophysiology of IBD and its extraintestinal manifestations. However, these data are quite preliminary. More studies are needed on a larger number of patients of different clinical severity in which the influence of various clinical and laboratory parameters such as the type of treatment they receive must be taken into account. The complexity of the pathophysiological factors involved in the pathogenesis of the disease does not allow easy or premature conclusions to be drawn about the actual pathogenetic role of various factors, including GDF-15. As pointed out by the authors, further investigation of the various molecular pathways in which GDF-15 is involved is required before definitive conclusions can be drawn."
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Tonkic A, Kumric M, Akrapovic Olic I, Rusic D, Zivkovic PM, Supe Domic D, Sundov Z, Males I, Bozic J. Growth differentiation factor-15 serum concentrations reflect disease severity and anemia in patients with inflammatory bowel disease. World J Gastroenterol 2024; 30(13): 1899-1910 [PMID: 38659482 DOI: 10.3748/wjg.v30.i13.1899]
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36
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"The installation of a tunnel peritoneal drainage catheter (PleurX or Rocket) for the palliative treatment of refractory ascites in cirrhotic patients, as well as its comparison with large volume paracenteses, is well described in previous studies. The authors demonstrated the feasibility of using long-term abdominal drains (LTAD) Rocket as a potential treatment method for refractory ascites in cirrhotic patients, with a comparable frequency of drain-related complications, peritonitis, cellulitis, site leakage, bleeding of drain site and hypotension in large volume paracentesis (LVP) and LTAD groups, with a higher incidence of ascites/drain related admissions and acute kidney injury in the LVP group, and with a longer time to first hospitalisation in the LTAD group. It should be noted that the decision to prescribe antibiotics as primary prophylaxis to all trial participants deviates from national and international guidance and makes it more difficult to rebut fears of increased infection risk. Long-term prophylactic antibiotic use is not without risk, both to the individual and wider population, and how this is approached in subsequent trial requires thought. "
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Kaur S, Motta RV, Chapman B, Wharton V, Collier JD, Saffioti F. Palliative long-term abdominal drains vs large volume paracenteses for the management of refractory ascites in end-stage liver disease. World J Hepatol 2024; 16(3): 428-438 [PMID: 38577536 DOI: 10.4254/wjh.v16.i3.428]
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37
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"1 Ethics: Informed written consent was obtained from the patient to publish this report and any accompanying images.
2 Methods: The description is exact and can be repeated according to adequate textual/citation content presented.
3 Results: The results look true and authentic. This is an extremely rare condition, and it is difficult to discuss its universal significance and whether it is validated or partially validated.
4 Figures and tables: The authors provide perfect tables, line charts and/or graphs.
5 Biostatistics: This is a case report without the possibility of statistics.
6 References: The authors scientifically and reasonably cite the latest references, which are important in this field and related to the scientific problems and research hypotheses addressed in the study.
7 Language: The language in the article looks correct, clear, and concisely expresses the information. Unfortunately, I am not a native English speaker.
8 Caveats or drawbacks: The part of the sentence ‘’but a suspicious positive Murphy sign was noted.’’ Is not scientifically correct. If the sign is positive, then it cannot be suspicious. Also, how can a sign be suspicious? The history was not suggestive of cholecystitis. It sounds more like an indolent course, which is suggestive of a tumor. Also, such irregularities on a CT scan are not suggestive of cholecystitis. If the diagnosis was cholecystitis with the resultant liver abscess, the treatment should be surgical. Percutaneous drainage cannot cure perforated cholecystitis, which is a cause of hepatic abscess. Therefore, this management plan was incorrect."
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Dai Y, Meng M, Luo QZ, Liu YJ, Xiao F, Wang CH. Gallbladder carcinosarcoma with a poor prognosis: A case report. World J Clin Cases 2024; 12(10): 1817-1823 [PMID: 38660083 DOI: 10.12998/wjcc.v12.i10.1817]
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38
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"The design of the subject is meticulous, the research direction is novel, and it has certain clinical value."
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Zhang T, Zhu S, Huang GW. ALKBH5 suppresses autophagic flux via N6-methyladenosine demethylation of ZKSCAN3 mRNA in acute pancreatitis. World J Gastroenterol 2024; 30(12): 1764-1776 [PMID: 38617741 DOI: 10.3748/wjg.v30.i12.1764]
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39
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"Bareno 7 criteria was personalized care for portal hypertension. TIPS become good tool for preventing esophageal varicose, decompression of liver cirrhosis."
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Shaaban HE, Abdellatef A, Okasha HH. Hepatic recompensation according to Baveno VII criteria via transjugular intrahepatic portosystemic shunt. World J Gastroenterol 2024; 30(12): 1777-1779 [PMID: 38617737 DOI: 10.3748/wjg.v30.i12.1777]
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40
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"Thank you for the opportunity to evaluate the quality of the following manuscript. Please see my comments below.
1 Ethics: Not applicable given manuscript type
2 Methods: Not applicable given manuscript type
3 Results: Not applicable given manuscript type
4 Figures and tables: The table summarizing existing evidence is extremely helpful. The authors included valuable figures illustrating the application of the EndoRotor Device
5 Biostatistics: Not applicable given manuscript type
6 References: Recent/appropriate references included
7 Language: This manuscript is succint and well written
8 Caveats or drawbacks: None"
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Zaghloul M, Rehman H, Sansone S, Argyriou K, Parra-Blanco A. Endoscopic treatment of scarred polyps with a non-thermal device (Endorotor): A review of the literature. World J Gastroenterol 2024; 30(12): 1706-1713 [PMID: 38617738 DOI: 10.3748/wjg.v30.i12.1706]
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41
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"This article provides significant insights into the correlations between the onset or development of NAFLD and sleep disorders. Poor sleep quality associated or not associated with short sleep duration, or even excessive sleep duration, may increase the risk of NAFLD. Sleep disorders are often associated with OSA, which in turn has been associated with the development of NAFLD. NAFDL itself appears to represent an aggravation risk for OSA, in a vicious cycle that is sometimes very difficult to eradicate.
The authors underline how, in certain circumstances, the treatment of OSA pathology with CPAP can stabilize and slow down the progression of NAFDL. The authors also highlights very well the reasons why improving sleep quality and resolving sleep disorders should be included in the list of lifestyle behaviours that can help reduce the risk of NAFLD.
I think the review may contribute adequately to raising teh reader's interest."
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Bu LF, Xiong CY, Zhong JY, Xiong Y, Li DM, Hong FF, Yang SL. Non-alcoholic fatty liver disease and sleep disorders. World J Hepatol 2024; 16(3): 304-315 [PMID: 38577533 DOI: 10.4254/wjh.v16.i3.304]
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42
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"The design of the research scheme meets the scientific requirements, the outcome factors included in the study are relatively comprehensive and rich, and the sample size is large, which can prove the conclusion."
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Yang LM, Wang HJ, Li SL, Gan GH, Deng WW, Chang YS, Zhang LF. Efficacy of radiofrequency ablation combined with sorafenib for treating liver cancer complicated with portal hypertension and prognostic factors. World J Gastroenterol 2024; 30(11): 1533-1544 [PMID: 38617449 DOI: 10.3748/wjg.v30.i11.1533]
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43
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"It is an interesting approach by Moluodan to the β-Catenin signaling pathway in H. pylori-mediated precancerous lesions"
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Wang YM, Luo ZW, Shu YL, Zhou X, Wang LQ, Liang CH, Wu CQ, Li CP. Effects of Helicobacter pylori and Moluodan on the Wnt/β-catenin signaling pathway in mice with precancerous gastric cancer lesions. World J Gastrointest Oncol 2024; 16(3): 979-990 [PMID: 38577474 DOI: 10.4251/wjgo.v16.i3.979]
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44
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"It is a well-arranged review for integrating the immune microenvironment in risk assessment and treatment strategies for colorectal cancer."
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Kuznetsova O, Fedyanin M, Zavalishina L, Moskvina L, Kuznetsova O, Lebedeva A, Tryakin A, Kireeva G, Borshchev G, Tjulandin S, Ignatova E. Prognostic and predictive role of immune microenvironment in colorectal cancer. World J Gastrointest Oncol 2024; 16(3): 643-652 [PMID: 38577454 DOI: 10.4251/wjgo.v16.i3.643]
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45
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"There is useful information for understanding Solid pseudopapillary tumors of the pancreas.
"
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Xu YC, Fu DL, Yang F. Unraveling the enigma: A comprehensive review of solid pseudopapillary tumor of the pancreas. World J Gastrointest Oncol 2024; 16(3): 614-629 [PMID: 38577449 DOI: 10.4251/wjgo.v16.i3.614]
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46
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"There is useful information on acute obstruction, often the first sign of advanced colorectal carcinoma especially in elderly individuals. "
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Pavlidis ET, Galanis IN, Pavlidis TE. Management of obstructed colorectal carcinoma in an emergency setting: An update. World J Gastrointest Oncol 2024; 16(3): 598-613 [PMID: 38577464 DOI: 10.4251/wjgo.v16.i3.598]
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47
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"This is an editorial full of valuable information."
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Triantafillidis JK, Georgiou K, Konstadoulakis MM, Papalois AE. Early-onset gastrointestinal cancer: An epidemiological reality with great significance and implications. World J Gastrointest Oncol 2024; 16(3): 583-597 [PMID: 38577465 DOI: 10.4251/wjgo.v16.i3.583]
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48
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"It is a valuable editorial."
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Jiang QY, Xue RY. Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio: Markers predicting immune-checkpoint inhibitor efficacy and immune-related adverse events. World J Gastrointest Oncol 2024; 16(3): 577-582 [PMID: 38577447 DOI: 10.4251/wjgo.v16.i3.577]
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49
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"It is a valuable editorial."
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Shenoy S. Synchronous gastric and colon cancers: Important to consider hereditary syndromes and chronic inflammatory disease associations. World J Gastrointest Oncol 2024; 16(3): 571-576 [PMID: 38577475 DOI: 10.4251/wjgo.v16.i3.571]
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50
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"Transplanting stool from healthy individuals to patients with ulcerative colitis is a well-established and effective method of treating moderate to severe relapses of the disease. However, the method is not widely applied for reasons related to inherent difficulties in its application and the availability of stool samples. However, in patients with Crohn's disease (CD), there is limited data on the application of the method. The so-called “Washed Microbiota Transplantation (WMT) is a promising therapeutic modality for the treatment of patients with CD. In a related prospective study on the efficacy of WMT in patients with CD, the authors found that (although the patient sample was very small) 63.6% of patients showed a significant improvement in the disease activity index three months after its application, but this was not accompanied by a concomitant reduction in blood and stool inflammation markers probably due to the small number of patients tested. Stool transplantation using the proposed technique is based on an automatic washing process. The exact mode of action of fecal transplantation needs to be further elucidated. In my opinion shortly and as long as the WMT technique becomes widely available and its cost becomes 'reasonable' it may compete with biological agents in the treatment of patients either as a single or as a combination therapy with biological and/or other available therapeutic agents. It goes without saying that what is also pointed out by the authors is that additional large randomized controlled trials using additional genomic techniques (e.g. macro-proteomics and culture genomics) are required to confirm the results of this study."
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Chen SJ, Zhang DY, Wu X, Zhang FM, Cui BT, Huang YH, Zhang ZL, Wang R, Bai FH. Washed microbiota transplantation for Crohn’s disease: A metagenomic, metatranscriptomic, and metabolomic-based study. World J Gastroenterol 2024; 30(11): 1572-1587 [PMID: 38617453 DOI: 10.3748/wjg.v30.i11.1572]
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