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1
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"This case may be interesting to the readers. Thanks for reviewing the previous literatures."
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Chen JC, Zhuang DZ, Luo C, Chen WQ. Malignant pheochromocytoma with cerebral and skull metastasis: A case report and literature review. World J Clin Cases 2021; 9(12): 2791-2800 [DOI: 10.12998/wjcc.v9.i12.2791]
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2
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"This case may be interesting to the readers."
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Zhao LW, Sun J, Wang YY, Hua RM, Tai SC, Wang K, Fan Y. Prostate stromal tumor with prostatic cysts after transurethral resection of the prostate: A case report. World J Clin Cases 2021; 9(12): 2830-2837 [DOI: 10.12998/wjcc.v9.i12.2830]
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3
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"This may be interesing to the readers."
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Hu WK, Liu J, Liu RX, Liu XW, Yin CH. Congenital bilateral cryptorchidism in an infant conceived after maternal breast cancer treatment: A case report. World J Clin Cases 2021; 9(12): 2923-2929 [DOI: 10.12998/wjcc.v9.i12.2923]
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4
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"Novel and practical for COVID times !!"
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Akahoshi K, Tamura S, Akahoshi K, Kaneshiro Y, Sashihara R, Uemura K, Sato K. Vinyl bag cover method to avoid droplet-containing aerosol escape from endoscopic forceps channel caps during COVID-19 pandemic (with video). World J Gastrointest Endosc 2021; 13(4): 111-114 [DOI: 10.4253/wjge.v13.i4.111]
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5
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"The study does bring out some practical although obvious points. It would have been interesting if analysis would have included elective vs. emergency procedures and ERCP procedures. It is expected that the sedation requirements for emergency procedures would be different so as for ERCP"
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Passi M, Rahman F, Gurram S, Kumar S, Koh C. Identifying who best tolerates moderate sedation: Results from a National Database of Gastrointestinal Endoscopic outcomes. World J Gastrointest Endosc 2021; 13(4): 97-110 [DOI: 10.4253/wjge.v13.i4.97]
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6
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"Authors present studies showing positive effect of short- and long-term exposure to hypoxic conditions during exercise. Despite there are some conflicting results of studies, most showed that hypoxic exercising may improve glucose uptake and insulin sensitivity in T2DM patients more than when exercising under normoxic conditions. Important is that authors also present possible health risks of exercise under the hypoxic condition and those patients should be advised by a medical doctor before exercise."
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Kim SW, Jung WS, Chung S, Park HY. Exercise intervention under hypoxic condition as a new therapeutic paradigm for type 2 diabetes mellitus: A narrative review. World J Diabetes 2021; 12(4): 331-343 [DOI: 10.4239/wjd.v12.i4.331]
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7
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"As the authors described that superficial CD34-positive fibroblastic tumor (SCPFT) is a newly discovered mesenchymal tumor that is mainly composed of fibroblasts. Given the lack of established diagnostic criteria, SCPFT is associated with a high misdiagnosis rate. This retrospective study analyzed the clinicopathological, immunohistochemical, and fluorescence in situ hybridization characteristics of four SCPFT patients. They provided useful information about the histopathological characteristics and genetic characteristics of this entity, which can help pathologists diagnose the disease more accurately. The figures and tables were good. The authors made a detailed discussion about the histopathological characteristics and differential diagnosis of SCPFT, which was instructive for pathologists. It will be better to summarize the previous reported cases and current cases in a table."
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Ding L, Xu WJ, Tao XY, Zhang L, Cai ZG. Clinicopathological features of superficial CD34-positive fibroblastic tumor. World J Clin Cases 2021; 9(12): 2739-2750 [DOI: 10.12998/wjcc.v9.i12.2739]
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8
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"The incidence of Budd-Chiari syndrome is low, and it is difficult to diagnose . Some medical personnel know little about this disease, and the misdiagnosis rate of the first diagnosis is high.This study reported a case of Budd-Chiari syndrome initially misdiagnosed as cirrhosis, alerting us to avoid misdiagnosis of the disease. BCS was confirmed by examination such as phlebography, and the obstructed inferior vena cava was re-opened by balloon angioplasty, and the patient's symptoms completely disappeared.It shows us the process of diagnosis and treatment of the disease. The results are authentic, the picture format is correct, and the language is concise and clear, which has certain research value."
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Ye QB, Huang QF, Luo YC, Wen YL, Chen ZK, Wei AL. Budd-Chiari syndrome associated with liver cirrhosis: A case report. World J Clin Cases 2021; 9(12): 2937-2943 [DOI: 10.12998/wjcc.v9.i12.2937]
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9
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"Reviews on the use of technology to treat psychiatric disorders have become commonplace during the period of the pandemic. All of them list various ICT based treatments that appear promising. They generally tend to be less critical of these treatments and avoid focusing on the limitations of these treatments. This review suffered from the same faults. Moreover, I do not think it added substantially to the existing literature. "
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Shu S, Woo BK. Use of technology and social media in dementia care: Current and future directions. World J Psychiatr 2021; 11(4): 109-123 [DOI: 10.5498/wjp.v11.i4.109]
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10
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"The methodological aspects of this meta-analysis were adequate. However, there is a leck of precision in the way the manuscript has been written. For example the basic format of psychotherapeutic treatments is same whether they are delivered in-person or by web-based platforms. Thus, descriptions of CBT or MBT in the introduction were superfluous. The central question, was whether the treatments performed equally well in-person and on the net. This has not really been addressed. There are other problems. In different parts of the paper the authors use the term "intervention" as if there is one single intervention, which is obviously not true. Moderators of treatment efficacy should have been discussed at greater length because they have important implication for the delivery of web-based psychotherapies.
"
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Lau Y, Cheng JY, Wong SH, Yen KY, Cheng LJ. Effectiveness of digital psychotherapeutic intervention among perinatal women: A systematic review and meta-analysis of randomized controlled trials. World J Psychiatr 2021; 11(4): 133-152 [DOI: 10.5498/wjp.v11.i4.133]
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11
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"This is an intriguing study that shows the power of bile acid measurement in distinguishing the presence of liver disease from its absence. It is difficult to tell from Table 8 whether such analysis can distinguish disorders in which cholestasis predominates from those in which hepatocellular injury predominates, the study may not have been powered to do this. The most interesting possibility is that bile acid analysis could be used to complement or refine scoring systems currently used to estimate the probability of liver-related adverse outcomes."
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Alamoudi JA, Li W, Gautam N, Olivera M, Meza J, Mukherjee S, Alnouti Y. Bile acid indices as biomarkers for liver diseases I: Diagnostic markers. World J Hepatol 2021; 13(4): 433-455 [DOI: 10.4254/wjh.v13.i4.433]
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12
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"This is a well-rounded review of a topic in evolution. The take-home message is pretty clear - we need more information from ongoing clinical trials before long term albumin infusion becomes a standard of care in cirrhosis."
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Wong YJ, Kumar R, Chua YJJ, Ang TL. Long-term albumin infusion in decompensated cirrhosis: A review of current literature . World J Hepatol 2021; 13(4): 421-432 [DOI: 10.4254/wjh.v13.i4.421]
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13
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"This is a study from Cecati and colleagues, investigating the potential role of the chemokine CXCL12 in the pathogenesis of pancreatic ductal adenocarcinoma (PDAC). Because CXCL12 pre-mRNA can be alternatively spliced into different isoforms (α, β, γ, δ, ε, θ), the investigators proposed to explore their specific roles in PDAC onset. Their findings, based on in vitro studies, suggest that α, β and γ CXCL12 isoforms can trigger different responses in a pancreatic pre-tumour model. The γ isoform induced the highest level of cell migration.
The study subject is relevant and the experimental design is well elaborated. The text is well written and the data is well presented using informative tables and clear figures with adequate legends. The methodology is appropriate and there are no ethical issues or problems in statistical analysis. The paper is based on in vitro studies, using an interesting model that allows indirect insights into the pathogenesis of PDAC.
"
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Cecati M, Giulietti M, Righetti A, Sabanovic B, Piva F. Effects of CXCL12 isoforms in a pancreatic pre-tumour cellular model: Microarray analysis. World J Gastroenterol 2021; 27(15): 1616-1629 [DOI: 10.3748/wjg.v27.i15.1616]
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14
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"This is a comprehensive description of the histological spectrum of primary hepatic malignancies that should be of great practical value to the community of pathologists, a group that must deal with diagnostic dilemmas that occur when multiphasic dynamic liver imaging does not provide definitive information. It would have been helpful to know the extent to which liver histology guides cancer treatment, but I am sure that space limitations prevented this."
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Vij M, Calderaro J. Pathologic and molecular features of hepatocellular carcinoma: An update. World J Hepatol 2021; 13(4): 393-410 [DOI: 10.4254/wjh.v13.i4.393]
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15
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"I would suggest to extend these results assessing PBC patients as a function of UDCA and obeticholic acid treatment. "
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Alamoudi JA, Li W, Gautam N, Olivera M, Meza J, Mukherjee S, Alnouti Y. Bile acid indices as biomarkers for liver diseases I: Diagnostic markers. World J Hepatol 2021; 13(4): 433-455 [DOI: 10.4254/wjh.v13.i4.433]
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16
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"Clinically relevant work"
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Tognarelli A, Faggioni L, Erba AP, Faviana P, Durante J, Manassero F, Selli C. Robotically assisted removal of pelvic splenosis fifty-six years after splenectomy: A case report. World J Clin Cases 2021; 9(12): 2868-2873 [DOI: 10.12998/wjcc.v9.i12.2868]
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17
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"Clinically relevant work"
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Zippi M, Fiorino S, Budriesi R, Micucci M, Corazza I, Pica R, de Biase D, Gallo CG, Hong W. Paradoxical relationship between proton pump inhibitors and COVID-19: A systematic review and meta-analysis. World J Clin Cases 2021; 9(12): 2763-2777 [DOI: 10.12998/wjcc.v9.i12.2763]
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18
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"Very good article"
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Ye QB, Huang QF, Luo YC, Wen YL, Chen ZK, Wei AL. Budd-Chiari syndrome associated with liver cirrhosis: A case report. World J Clin Cases 2021; 9(12): 2937-2943 [DOI: 10.12998/wjcc.v9.i12.2937]
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19
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"Very good article"
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Hu WK, Liu J, Liu RX, Liu XW, Yin CH. Congenital bilateral cryptorchidism in an infant conceived after maternal breast cancer treatment: A case report. World J Clin Cases 2021; 9(12): 2923-2929 [DOI: 10.12998/wjcc.v9.i12.2923]
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20
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"Very good article"
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Uchihashi T, Kodama S, Sugauchi A, Hiraoka S, Hirose K, Usami Y, Tanaka S, Kogo M. Salivary duct carcinoma of the submandibular gland presenting a diagnostic challenge: A case report. World J Clin Cases 2021; 9(12): 2908-2915 [DOI: 10.12998/wjcc.v9.i12.2908]
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21
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"Very good article"
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Wu XK, Lin Q. Pulmonary alveolar proteinosis complicated with nocardiosis: A case report and review of the literature. World J Clin Cases 2021; 9(12): 2874-2883 [DOI: 10.12998/wjcc.v9.i12.2874]
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22
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"Very good article"
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Jiang Y, Lo R, Lu ZQ, Cheng XB, Xiong L, Luo BF. Successful endoscopic surgery for emphysematous pyelonephritis in a non-diabetic patient with autosomal dominant polycystic kidney disease: A case report. World J Clin Cases 2021; 9(12): 2862-2867 [DOI: 10.12998/wjcc.v9.i12.2862]
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23
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"Very good article"
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Xie WX, Jiang HT, Shi GQ, Yang LN, Wang H. Behcet’s disease manifesting as esophageal variceal bleeding: A case report. World J Clin Cases 2021; 9(12): 2854-2861 [DOI: 10.12998/wjcc.v9.i12.2854]
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24
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"Interesting paper"
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Yuan SY, Xie KF, Yang J. Intramuscular hematoma in rhabdomyolysis patients treated with low-molecular-weight heparin: Report of two cases. World J Clin Cases 2021; 9(12): 2838-2844 [DOI: 10.12998/wjcc.v9.i12.2838]
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25
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"Interesting paper"
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Zhao LW, Sun J, Wang YY, Hua RM, Tai SC, Wang K, Fan Y. Prostate stromal tumor with prostatic cysts after transurethral resection of the prostate: A case report. World J Clin Cases 2021; 9(12): 2830-2837 [DOI: 10.12998/wjcc.v9.i12.2830]
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26
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"Interesting paper"
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Yu TT, Yu H, Cui Y, Liu W, Cui XY, Wang X. Laryngeal myxoma: A case report. World J Clin Cases 2021; 9(12): 2823-2829 [DOI: 10.12998/wjcc.v9.i12.2823]
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27
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"Interesting paper"
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Chen JC, Zhuang DZ, Luo C, Chen WQ. Malignant pheochromocytoma with cerebral and skull metastasis: A case report and literature review. World J Clin Cases 2021; 9(12): 2791-2800 [DOI: 10.12998/wjcc.v9.i12.2791]
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28
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"Very good article"
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Ma YH, Tian ZS, Liu HC, Zhang BY, Zhu YH, Meng CY, Liu XJ, Zhu QS. Predictive risk factors for recollapse of cemented vertebrae after percutaneous vertebroplasty: A meta-analysis . World J Clin Cases 2021; 9(12): 2778-2790 [DOI: 10.12998/wjcc.v9.i12.2778]
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29
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"Very good article"
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Taweesedt PT, Surani S. Mediastinal lymphadenopathy in COVID-19: A review of literature. World J Clin Cases 2021; 9(12): 2703-2710 [DOI: 10.12998/wjcc.v9.i12.2703]
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30
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"Very good article"
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Wang CS, Gao Y, Kang K, Fei DS, Meng XL, Liu HT, Luo YP, Yang W, Dai QQ, Gao Y, Zhao MY, Yu KJ. Standardization of critical care management of non-critically ill patients with COVID-19 . World J Clin Cases 2021; 9(12): 2696-2702 [DOI: 10.12998/wjcc.v9.i12.2696]
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31
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"This is a very comprehensive, well researched report. The patient was fortunate to have such a million dollar workup and thoughtful follow up. I have only two constructive comments to make.
Firstly, a more professional presentation of the EKGs would have been helpful. Magnification of the recovery tracings would enable better presentation of the Q-T interval
Secondly, the paper's discussion is too technical for most practicing cardiologists to appreciate. While the conclusions are understandable, the methodology is too complex for a "clinical" journal."
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Qiu H, Li HW, Zhang SH, Zhou XG, Li WP. Torsades de pointes episode in a woman with high-grade fever and inflammatory activation: A case report. World J Clin Cases 2021; 9(12): 2899-2907 [DOI: 10.12998/wjcc.v9.i12.2899]
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32
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"The authors could add a systematic review to further analyze the superficial CD34-positive fibroblastic tumor.
"
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Ding L, Xu WJ, Tao XY, Zhang L, Cai ZG. Clinicopathological features of superficial CD34-positive fibroblastic tumor. World J Clin Cases 2021; 9(12): 2739-2750 [DOI: 10.12998/wjcc.v9.i12.2739]
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33
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"Technically, a convincing contribution. Albeit the side comment on the problems with sorting cells using LGR5-antibodies might be of interest to many paople considering LGR5 as the holy grale of intestinal cancer stemness. Another puzzling technical issue is the lack of information on STR-testing of the used cell line clones - they were originally from the ATCC, but only indirectly since in the Acknowledgements, the authors thank Professor McGuckin. Especially when analyzing cell line individual features, the lack of this information diminishes it's usefullness for many scientific nit-pickers like me.
I would like to add an alternative interpretation of these, and many similar results on stem cells in CRC cell lines: the fact that LGR5 negative cells and cell lines regularly grow nicely in vitro and when carefully looking on the in vivo data of this manuscript often also in vivo, is regularly ignored by many researchers. The same is in our experience also true for many other of the candidate tumor stem cell markers and even for the funcitonally more convincing side population (classically done by Hoechst staining).
Thus, the true level of plasticity in CRC cells is in biological reality most likely indeed very high!
Part of this complexity has been adressed in the last part of the discussion - which was a pleasure to read.
"
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Alharbi SA, Ovchinnikov DA, Wolvetang E. Leucine-rich repeat-containing G protein-coupled receptor 5 marks different cancer stem cell compartments in human Caco-2 and LoVo colon cancer lines. World J Gastroenterol 2021; 27(15): 1578-1594 [DOI: 10.3748/wjg.v27.i15.1578]
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34
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"Article "Impact of cytokine storm and systemic inflammation on liver impairment patients infected by SARS-CoV-2: Prospective therapeutic challenges" presents the most important knowledge about the SARS-CoV-2 virus and the impact of the virus on the liver as the importance of inflammation in the pathophysiology of infection and potential therapeutic options."
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Ali FEM, Mohammedsaleh ZM, Ali MM, Ghogar OM. Impact of cytokine storm and systemic inflammation on liver impairment patients infected by SARS-CoV-2: Prospective therapeutic challenges. World J Gastroenterol 2021; 27(15): 1531-1552 [DOI: 10.3748/wjg.v27.i15.1531]
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35
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"nice case report"
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Yang QH, Ma XP, Dai DL, Bai DM, Zou Y, Liu SX, Song JM. Gastrointestinal cytomegalovirus disease secondary to measles in an immunocompetent infant: A case report. World J Gastroenterol 2021; 27(15): 1655-1663 [DOI: 10.3748/wjg.v27.i15.1655]
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36
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"basic manuscript"
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Liang XY, Jia TX, Zhang M. Intestinal bacterial overgrowth in the early stage of severe acute pancreatitis is associated with acute respiratory distress syndrome. World J Gastroenterol 2021; 27(15): 1643-1654 [DOI: 10.3748/wjg.v27.i15.1643]
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37
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"nice manuscript with potential for clinical impact"
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Muniraj T, Aslanian HR, Laine L, Jamidar PA, Farrell JF, Mitchell KA, Salem RR. Resection of pancreatic cystic neoplasms in recurrent acute pancreatitis prevents recurrent pancreatitis but does not identify more malignancies. World J Gastroenterol 2021; 27(15): 1630-1642 [DOI: 10.3748/wjg.v27.i15.1630]
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38
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"nice detailed manuscript"
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Cecati M, Giulietti M, Righetti A, Sabanovic B, Piva F. Effects of CXCL12 isoforms in a pancreatic pre-tumour cellular model: Microarray analysis. World J Gastroenterol 2021; 27(15): 1616-1629 [DOI: 10.3748/wjg.v27.i15.1616]
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39
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"nice detailed manuscript.
nice images"
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Li K, Peng YF, Guo JZ, Li M, Zhang Y, Chen JY, Lin TR, Yu X, Yu WD. Abelson interactor 1 splice isoform-L plays an anti-oncogenic role in colorectal carcinoma through interactions with WAVE2 and full-length Abelson interactor 1. World J Gastroenterol 2021; 27(15): 1595-1615 [DOI: 10.3748/wjg.v27.i15.1595]
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40
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"nice detailed manuscript"
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Alharbi SA, Ovchinnikov DA, Wolvetang E. Leucine-rich repeat-containing G protein-coupled receptor 5 marks different cancer stem cell compartments in human Caco-2 and LoVo colon cancer lines. World J Gastroenterol 2021; 27(15): 1578-1594 [DOI: 10.3748/wjg.v27.i15.1578]
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41
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"nice images.
a graph or drowing could improve teh impact"
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Sakai Y, Ohtsuka M, Sugiyama H, Mikata R, Yasui S, Ohno I, Iino Y, Kato J, Tsuyuguchi T, Kato N. Current status of diagnosis and therapy for intraductal papillary neoplasm of the bile duct. World J Gastroenterol 2021; 27(15): 1569-1577 [DOI: 10.3748/wjg.v27.i15.1569]
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42
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"very basic"
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Lorenzo-Zúñiga V, Bustamante-Balén M, Pons-Beltrán V. Prevention of late complications with coverage agents in endoscopic resection of colorectal lesions: Current landscape in gastrointestinal endoscopy. World J Gastroenterol 2021; 27(15): 1563-1568 [DOI: 10.3748/wjg.v27.i15.1563]
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43
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"consider mentioning MRI and defecograms"
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Sbeit W, Khoury T, Mari A. Diagnostic approach to faecal incontinence: What test and when to perform? World J Gastroenterol 2021; 27(15): 1553-1562 [DOI: 10.3748/wjg.v27.i15.1553]
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44
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"nice menuscript"
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Ali FEM, Mohammedsaleh ZM, Ali MM, Ghogar OM. Impact of cytokine storm and systemic inflammation on liver impairment patients infected by SARS-CoV-2: Prospective therapeutic challenges. World J Gastroenterol 2021; 27(15): 1531-1552 [DOI: 10.3748/wjg.v27.i15.1531]
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45
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"a graph could add impact to the paper"
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Tsilimigras DI, Pawlik TM, Moris D. Textbook outcomes in hepatobiliary and pancreatic surgery. World J Gastroenterol 2021; 27(15): 1524-1530 [DOI: 10.3748/wjg.v27.i15.1524]
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46
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"This article underlines the importance of non-surgical treatment in patient with full thickness rotator cuff tears. These findings could have a significant impact on the treatment of patients with rotator cuff tears in the future. Pre-treatment magnetic resonance imaging scans were used to evaluate the outcomes at 1 and 2 years after treatment, considering predictors of results. I think the well conducted story with good statistical analysis. The significance consists of remarking with statistical evidence the conservative treatment in this common patology, useful for preparation to further surgical treament too, if necessary
"
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Bush C, Gagnier JJ, Carpenter J, Bedi A, Miller B. Predictors of clinical outcomes after non-operative management of symptomatic full-thickness rotator cuff tears. World J Orthop 2021; 12(4): 223-233 [DOI: 10.5312/wjo.v12.i4.223]
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47
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"The review by Paczkowska-Abdulsalam & Kretowski is original and comprehensive, providing a thotorugh overview of a hot topic. I commend the authors for their work. "
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Paczkowska-Abdulsalam M, Kretowski A. Obesity, metabolic health and omics: Current status and future directions. World J Diabetes 2021; 12(4): 420-436 [DOI: 10.4239/wjd.v12.i4.420]
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48
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"Thank you for this presentation
This topic is out of my experience. Therefore, it is not very suitable for me to comment in terms of article content."
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Felmerer G, Behringer D, Emmerich N, Grade M, Stepniewski A. Donor defects after lymph vessel transplantation and free vascularized lymph node transfer: A comparison and evaluation of complications. World J Transplant 2021; 11(4): 129-137 [DOI: 10.5500/wjt.v11.i4.129]
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49
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" The present study mainly focus on the effects of exposure to hypoxic conditions on diabetes and considered ed that Exercise intervention under hypoxic condition as a new therapeutic paradigm for type 2 diabetes mellitus. I would like to argue the safety for those diabetic patients with potential hypoxemia and the risk for lactic acidemia."
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Kim SW, Jung WS, Chung S, Park HY. Exercise intervention under hypoxic condition as a new therapeutic paradigm for type 2 diabetes mellitus: A narrative review. World J Diabetes 2021; 12(4): 331-343 [DOI: 10.4239/wjd.v12.i4.331]
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50
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"Very nice and innovative method to prevent infection by disallowing infected aerosol to escape from a COVID-19-infected patient. Well-described.
"
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Akahoshi K, Tamura S, Akahoshi K, Kaneshiro Y, Sashihara R, Uemura K, Sato K. Vinyl bag cover method to avoid droplet-containing aerosol escape from endoscopic forceps channel caps during COVID-19 pandemic (with video). World J Gastrointest Endosc 2021; 13(4): 111-114 [DOI: 10.4253/wjge.v13.i4.111]
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