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Article Quality Tracking-Peer-Review
Publication Name
Article Title
Manuscript ID Reviewer Code
Year Published Author(s)
1
"This is an interesting review of current and future systemic treatment for HCC." 
Urquijo-Ponce JJ, Alventosa-Mateu C, Latorre-Sánchez M, Castelló-Miralles I, Diago M. Present and future of new systemic therapies for early and intermediate stages of hepatocellular carcinoma. World J Gastroenterol 2024; 30(19): 2512-2522 [DOI: 10.3748/wjg.v30.i19.2512]
2
"This is a very interesting article for managing a condition that is sometimes very difficult to handle during acute bleeding" 
Riccioni ME, Marmo C. Outpatient management of obscure gastrointestinal bleeding: A new perspective in high-risk patients. World J Gastroenterol 2024; 30(19): 2502-2504 [DOI: 10.3748/wjg.v30.i19.2502]
3
"The authors have summarized current knowledge about breast-cancer brain metastasis. The manuscript is well written, but lacks originality." 
Karthik J, Sehrawat A, Kapoor M, Sundriyal D. Navigating breast cancer brain metastasis: Risk factors, prognostic indicators, and treatment perspectives. World J Clin Oncol 2024; 15(5): 594-598 [DOI: 10.5306/wjco.v15.i5.594]
4
"Intestinal microecological transplantation is an effective treatment for relieving the clinical symptoms of chronic radiation enteritis by altering the composition of the intestinal flora. This study provides a new approach for treating patients with chronic radiation enteritis. " 
Wang L, Li Y, Zhang YJ, Peng LH. Intestinal microecological transplantation for a patient with chronic radiation enteritis: A case report. World J Gastroenterol 2024; 30(19): 2603-2611 [DOI: 10.3748/wjg.v30.i19.2603]
5
"In this review article, the authors summarize the current knowledge of systemic treatments for hepatocellular carcinoma, specifically aiming to further prolong prognosis after curative-intent treatment and adjuvant treatments for downstaging tumors to make them suitable for locoregional treatments. Reports of clinical trials related to these concepts are listed and briefly commented on. Unfortunately, the article does not provide a clear context for identifying who the ideal candidates are for systemic treatments, nor does it offer a rational explanation for combining multiple medications such as immune checkpoint inhibitors and thymidine kinase inhibitors. There should be a hypothesis explaining the rationale for each regimen in clinical trials." 
Urquijo-Ponce JJ, Alventosa-Mateu C, Latorre-Sánchez M, Castelló-Miralles I, Diago M. Present and future of new systemic therapies for early and intermediate stages of hepatocellular carcinoma. World J Gastroenterol 2024; 30(19): 2512-2522 [DOI: 10.3748/wjg.v30.i19.2512]
6
"It is with pleasure that I review the quality of this editorial on immunotherapy for esophageal cancer. Please see my comments below 1 Ethics: Not applicable given manuscript type 2 Methods: Not applicable given manuscript type 3 Results: Not applicable given manuscript type 4 Figures and tables: The included tables aids in the readability of the manuscript 5 Biostatistics: Not applicable given manuscript type 6 References: The references are timely and appropriate 7 Language: This is a succint and well written editorial 8 Caveats or drawbacks: None" 
Shoji Y, Koyanagi K, Kanamori K, Tajima K, Ogimi M, Ninomiya Y, Yamamoto M, Kazuno A, Nabeshima K, Nishi T, Mori M. Immunotherapy for esophageal cancer: Where are we now and where can we go. World J Gastroenterol 2024; 30(19): 2496-2501 [DOI: 10.3748/wjg.v30.i19.2496]
7
"Dear Dr. Zheng and colleagues, I recently read your article, "Protein arginine methyltransferase 6 is a novel substrate of protein arginine methyltransferase 1," published in the World Journal of Biological Chemistry. Your research gives significant ideas about the interaction between PRMT1 and PRMT6, particularly focusing on the methylation of PRMT6 by PRMT1 at the R106 site and its roles for enzymatic activity regulation. The methodologies of your study, especially the LC-MS/MS analysis were well-written and impressive and demonstrated a high level of scientific efforts. I was fascinated by your findings on how PRMT1 downregulates PRMT6's activity in histone H3 methylation, which increases our understanding of post-translational modifications and their roles in disease progression." 
Cao MT, Feng Y, Zheng YG. Protein arginine methyltransferase 6 is a novel substrate of protein arginine methyltransferase 1. World J Biol Chem 2023; 14(5): 84-98 [PMID: 37901302 DOI: 10.4331/wjbc.v14.i5.84]
8
"It is well-described the importance of the ALBI levels in HCC patients with thrombocytopeniaa." 
Man ZR, Gong XK, Qu KL, Pang Q, Wu BQ. Albumin–bilirubin grade as a predictor of survival in hepatocellular carcinoma patients with thrombocytopenia. World J Gastrointest Oncol 2024; 16(5): 1763-1772 [PMID: 38764822 DOI: 10.4251/wjgo.v16.i5.1763]
9
"It is a well-arranged review of stat signaling, a critical marker of immunotherapies." 
Sánchez-Ramírez D, Mendoza-Rodríguez MG, Alemán OR, Candanedo-González FA, Rodríguez-Sosa M, Montesinos-Montesinos JJ, Salcedo M, Brito-Toledo I, Vaca-Paniagua F, Terrazas LI. Impact of STAT-signaling pathway on cancer-associated fibroblasts in colorectal cancer and its role in immunosuppression. World J Gastrointest Oncol 2024; 16(5): 1705-1724 [PMID: 38764833 DOI: 10.4251/wjgo.v16.i5.1705]
10
"It is interesting to describe about the role of IL-1b related to GC." 
Khawkhiaw K, Panaampon J, Imemkamon T, Saengboonmee C. Interleukin-1β: Friend or foe for gastrointestinal cancers. World J Gastrointest Oncol 2024; 16(5): 1676-1682 [PMID: 38764841 DOI: 10.4251/wjgo.v16.i5.1676]
11
"Interesting case report." 
Shangguan PX, Zhou KC. Imaging characteristics and treatment strategies for carotid artery occlusion caused by skull base fracture: Three case reports. World J Clin Cases 2024; 12(15): 2664-2671 [DOI: 10.12998/wjcc.v12.i15.2664]
12
"This is an interesting case report." 
Alkhunayfir HA, AlQahtani AA, Korkoman AJ. Congenital absence of the lateral meniscus: A case report. World J Orthop 2024; 15(5): 477-482 [DOI: 10.5312/wjo.v15.i5.477]
13
"RS may offer a potential curative approach for lesions not amenable to percutaneous ablation or surgical resection, due to anatomical constraints, significant comorbidities, or low functional liver reserve. Unlike percutaneous therapies, RS has no risk of needle-track seeding, liver injury due to challenging anatomical locations, or development of arterioportal fistulas. While thermal ablation is generally accepted as a curative treatment option for lesions < 3 cm, RS demonstrates promise for achieving curative intent even in lesions up to 8 cm. RS is a wonderful tool for HCC compared to conventinal treatment. " 
Inchingolo R, Cortese F, Pisani AR, Acquafredda F, Calbi R, Memeo R, Anagnostopoulos F, Spiliopoulos S. Selective internal radiation therapy segmentectomy: A new minimally invasive curative option for primary liver malignancies? World J Gastroenterol 2024; 30(18): 2379-2386 [PMID: 38764771 DOI: 10.3748/wjg.v30.i18.2379]
14
"In this original manuscript, the authors aimed to identify clinical indicators of drug-induced liver injury using salivary samples. The analyses, which utilized ultrahigh-pressure liquid chromatography coupled with tandem mass spectrometry, revealed that metabolites in purine metabolism and the beta-oxidation of very long-chain fatty acids, notably 12-hydroxydodecanoic acid, 3-hydroxydecanoic acid, tetradecanedioic acid, hypoxanthine, and inosine, are promising molecules with diagnostic value. The authors reasoned that fatty acids and intermediates in the purine degradation pathway, such as hypoxanthine and inosine, could be markers of drug-induced liver injury because ATP and fatty acids are primarily released from and metabolized in the liver, respectively. Since the study design utilized healthy individuals as a control group, these markers could indicate liver injury but might not be specific to drug-induced liver injury. To identify molecules specific for drug-induced liver injury, the control group should consist of patients with liver injury not caused by adverse reactions to drugs." 
Yu SM, Zheng HC, Wang SC, Rong WY, Li P, Jing J, He TT, Li JH, Ding X, Wang RL. Salivary metabolites are promising noninvasive biomarkers of drug-induced liver injury. World J Gastroenterol 2024; 30(18): 2454-2466 [PMID: 38764769 DOI: 10.3748/wjg.v30.i18.2454]
15
"The editorial article by Barone M refers to the role of the renin-angiotensin system in the occurrence and progression of hepatic fibrosis and the role of autophagy of hepatic stellate cells in the development of hepatocellular carcinoma since the mechanisms involved in the genesis of hepatic fibrosis are also known to be involved in the process of carcinogenesis. It appears that angiotensin-converting enzyme inhibitors and angiotensin receptor blockers reduce hepatic fibrosis by regulating autophagy of hepatic stellate cells, representing at the same time potential therapeutic targets in patients with hepatocellular carcinoma. In particular, overexpression of Angiotensin-converting enzyme 2 inhibits hepatic stellate cell autophagy via the AMP-activated protein kinase/mammalian target of the rapamycin pathway. As the author concludes, investigation of the entire pathway will probably identify other points whose targeting will help in the treatment of both fibrosis and the development of hepatocellular carcinoma. Since angiotensin inhibitors reduce the expression of many mediators of fibrosis and inflammation, further research is needed to accurately define their role in hepatic fibrosis and carcinogenesis." 
Barone M. Angiotensin-converting enzyme 2 and AMPK/mTOR pathway in the treatment of liver fibrosis: Should we consider further implications? World J Gastroenterol 2024; 30(18): 2391-2396 [PMID: 38764773 DOI: 10.3748/wjg.v30.i18.2391]
16
"The problem in DILI is to distinguish it from other causes of hepatic injury and finding the target drug specially in those who have polypharmacy . This study with control group of health individuals could not sole these probelems.I wounder of the saliva of patients with other causes of hepatic injury for instance viral or autoimmune hepatitis were tested the result would have been different . " 
Yu SM, Zheng HC, Wang SC, Rong WY, Li P, Jing J, He TT, Li JH, Ding X, Wang RL. Salivary metabolites are promising noninvasive biomarkers of drug-induced liver injury. World J Gastroenterol 2024; 30(18): 2454-2466 [PMID: 38764769 DOI: 10.3748/wjg.v30.i18.2454]
17
"the article is on an interesting topic . A more concise review and raising the issue of cost and benefit would have increased the value of the article. " 
Selvanderan SP, Lam E, Shahidi N. Endohepatology: Arrival at the frontier of interventional endosonography. World J Gastroenterol 2024; 30(18): 2397-2401 [PMID: 38764768 DOI: 10.3748/wjg.v30.i18.2397]
18
"With interest I read this editorial. Please see my comments below: 1 Ethics: Not applicable given manuscript type 2 Methods: Not applicable given manuscript type 3 Results: Not applicable given manuscript type 4 Figures and tables: None provided 5 Biostatistics: Not applicable given manuscript type 6 References: The included references are timely/relevant 7 Language: This is a succint/well written editorial 8 Caveats or drawbacks: None" 
Cocca S, Pontillo G, Grande G, Conigliaro R. Artificial intelligence in detection of small bowel lesions and their bleeding risk: A new step forward. World J Gastroenterol 2024; 30(18): 2482-2484 [PMID: 38764765 DOI: 10.3748/wjg.v30.i18.2482]
19
"This is a fairly complex summary article on the development of an immunosuppressive tumor microenvironment in the esophagus. However, the role of several mechanisms would have been worth discussing: pro- and antitumor autophagy, the inflammasome, cancer stem cell formation, the immunomodulatory effects of sirtuins, and epigenetic factors. " 
Zhang XJ, Yu Y, Zhao HP, Guo L, Dai K, Lv J. Mechanisms of tumor immunosuppressive microenvironment formation in esophageal cancer. World J Gastroenterol 2024; 30(16): 2195-2208 [PMID: 38690024 DOI: 10.3748/wjg.v30.i16.2195]
20
"Their results are interesting." 
Zhou J, Zhang MY, Gao AA, Zhu C, He T, Herman JG, Guo MZ. Epigenetic silencing schlafen-11 sensitizes esophageal cancer to ATM inhibitor. World J Gastrointest Oncol 2024; 16(5): 2060-2073 [PMID: 38764821 DOI: 10.4251/wjgo.v16.i5.2060]
21
"This is a concise and well-edited editorial on the importance and use of endohepatology. The article is also a review of another study. The topic of the article could be further elaborated in the direction of how EUS can be combined with elastography to obtain high-quality diagnostic biopsy specimens for autoimmune liver diseases such as small duct PSC or autoimmune hepatitis overlap syndromes. " 
Selvanderan SP, Lam E, Shahidi N. Endohepatology: Arrival at the frontier of interventional endosonography. World J Gastroenterol 2024; 30(18): 2397-2401 [PMID: 38764768 DOI: 10.3748/wjg.v30.i18.2397]
22
"Their results are interesting." 
Wan XH, Jin GB, Yang Q, Hu JL, Liu ZL, Rao J, Wen C, Li PL, Yang XM, Huang B, Wang XZ. Novel miR-490-3p/hnRNPA1-b/PKM2 axis mediates the Warburg effect and proliferation of colon cancer cells via the PI3K/AKT pathway. World J Gastrointest Oncol 2024; 16(5): 2038-2059 [PMID: 38764836 DOI: 10.4251/wjgo.v16.i5.2038]
23
"Their results are interesting." 
Peng WB, Li YP, Zeng Y, Chen K. Transglutaminase 2 serves as a pathogenic hub gene of KRAS mutant colon cancer based on integrated analysis. World J Gastrointest Oncol 2024; 16(5): 2074-2090 [PMID: 38764826 DOI: 10.4251/wjgo.v16.i5.2074]
24
"Their results are interesting." 
Wang L, Gong WH. Predictive model using four ferroptosis-related genes accurately predicts gastric cancer prognosis. World J Gastrointest Oncol 2024; 16(5): 2018-2037 [PMID: 38764813 DOI: 10.4251/wjgo.v16.i5.2018]
25
"Their results are interesting." 
Kong LS, Tao R, Li YF, Wang WB, Zhao X. METTL5 promotes cell proliferation, invasion, and migration by up-regulating Toll-like receptor 8 expression in colorectal cancer. World J Gastrointest Oncol 2024; 16(5): 2006-2017 [PMID: 38764815 DOI: 10.4251/wjgo.v16.i5.2006]
26
"This study is well designed. " 
Hu KY, Cheng YQ, Shi ZL, Ren FP, Xiao GF. Casual associations between blood metabolites and colon cancer. World J Gastrointest Oncol 2024; 16(5): 1995-2005 [PMID: 38764807 DOI: 10.4251/wjgo.v16.i5.1995]
27
"This study is well designed. " 
Lu DD, Yuan L, Wang ZZ, Zhao JJ, Du YH, Ning N, Chen GQ, Huang SC, Yang Y, Zhang Z, Nan Y. To explore the mechanism of Yigong San anti-gastric cancer and immune regulation. World J Gastrointest Oncol 2024; 16(5): 1965-1994 [PMID: 38764819 DOI: 10.4251/wjgo.v16.i5.1965]
28
"This study is well designed. " 
Zhou JW, Zhang YB, Huang ZY, Yuan YP, Jin J. Identification of differentially expressed mRNAs as novel predictive biomarkers for gastric cancer diagnosis and prognosis. World J Gastrointest Oncol 2024; 16(5): 1947-1964 [PMID: 38764850 DOI: 10.4251/wjgo.v16.i5.1947]
29
"This study is well designed. " 
Zhang YQ, Li J, Qin Z, Li DM, Ye FZ, Bei SH, Zhang XH, Feng L. METTL5 promotes gastric cancer progression via sphingomyelin metabolism. World J Gastrointest Oncol 2024; 16(5): 1925-1946 [PMID: 38764837 DOI: 10.4251/wjgo.v16.i5.1925]
30
"This study is well designed." 
Wang HY, Diao Y, Tan PZ, Liang H. Four centrosome-related genes to predict the prognosis and drug sensitivity of patients with colon cancer. World J Gastrointest Oncol 2024; 16(5): 1908-1924 [PMID: 38764831 DOI: 10.4251/wjgo.v16.i5.1908]
31
"This study is well designed. " 
Jin XS, Chen LX, Ji TT, Li RZ. SERPINH1 promoted the proliferation and metastasis of colorectal cancer by activating PI3K/Akt/mTOR signaling pathway. World J Gastrointest Oncol 2024; 16(5): 1890-1907 [PMID: 38764814 DOI: 10.4251/wjgo.v16.i5.1890]
32
"This study is well designed." 
Fazal F, Khan MA, Shawana S, Rashid R, Mubarak M. Correlation of tumor-associated macrophage density and proportion of M2 subtypes with the pathological stage of colorectal cancer. World J Gastrointest Oncol 2024; 16(5): 1878-1889 [PMID: 38764849 DOI: 10.4251/wjgo.v16.i5.1878]
33
"This report is well written." 
Liu B, Zhang ZX, Nie XY, Sun WL, Yan YJ, Fu WH. Clinical outcome and prognostic factors of T4N0M0 colon cancer after R0 resection: A retrospective study. World J Gastrointest Oncol 2024; 16(5): 1869-1877 [PMID: 38764842 DOI: 10.4251/wjgo.v16.i5.1869]
34
"This report is well written. " 
Dogan O, Sahinli H, Duzkopru Y, Akdag T, Kocanoglu A. Is sarcopenia effective on survival in patients with metastatic gastric cancer? World J Gastrointest Oncol 2024; 16(5): 1861-1868 [PMID: 38764843 DOI: 10.4251/wjgo.v16.i5.1861]
35
"This report is well written." 
Ye YX, Yang L, Kang Z, Wang MQ, Xie XD, Lou KX, Bao J, Du M, Li ZX. Magnetic resonance imaging-based lymph node radiomics for predicting the metastasis of evaluable lymph nodes in rectal cancer. World J Gastrointest Oncol 2024; 16(5): 1849-1860 [PMID: 38764830 DOI: 10.4251/wjgo.v16.i5.1849]
36
"This report is well written. " 
Mu F, Hu LS, Xu K, Zhao Z, Yang BC, Wang YM, Guo K, Shi JH, Lv Y, Wang B. Perioperative remedial antiviral therapy in hepatitis B virus-related hepatocellular carcinoma resection: How to achieve a better outcome. World J Gastrointest Oncol 2024; 16(5): 1833-1848 [PMID: 38764825 DOI: 10.4251/wjgo.v16.i5.1833]
37
"This report is well written. " 
Ren X, Qu YP, Zhu CL, Xu XH, Jiang H, Lu YX, Xue HP. Percutaneous transhepatic cholangioscopy-assisted biliary polypectomy for local palliative treatment of intraductal papillary neoplasm of the bile duct. World J Gastrointest Oncol 2024; 16(5): 1821-1832 [PMID: 38764829 DOI: 10.4251/wjgo.v16.i5.1821]
38
"This report is well written." 
Chen HL, He RL, Gu MT, Zhao XY, Song KR, Zou WJ, Jia NY, Liu WM. Nomogram prediction of vessels encapsulating tumor clusters in small hepatocellular carcinoma ≤ 3 cm based on enhanced magnetic resonance imaging. World J Gastrointest Oncol 2024; 16(5): 1808-1820 [PMID: 38764811 DOI: 10.4251/wjgo.v16.i5.1808]
39
"This report is well written. " 
Mu RQ, Lv JW, Ma CY, Ma XH, Xing D, Ma HS. Diagnostic performance of dynamic contrast-enhanced magnetic resonance imaging parameters and serum tumor markers in rectal carcinoma prognosis. World J Gastrointest Oncol 2024; 16(5): 1796-1807 [PMID: 38764818 DOI: 10.4251/wjgo.v16.i5.1796]
40
"This study is well designed. " 
Xue JJ, Hu ST, Wang CC, Chen ZC, Cheng SY, Yu SQ, Peng HJ, Zhang YT, Zeng WJ. Prognostic relevance of ventricular arrhythmias in surgical patients with gastrointestinal tumors. World J Gastrointest Oncol 2024; 16(5): 1787-1795 [PMID: 38764817 DOI: 10.4251/wjgo.v16.i5.1787]
41
"This study is well designed." 
Chen JH, Zhu LY, Cai ZW, Hu X, Ahmed AA, Ge JQ, Tang XY, Li CJ, Pu YL, Jiang CY. TRIANGLE operation, combined with adequate adjuvant chemotherapy, can improve the prognosis of pancreatic head cancer: A retrospective study. World J Gastrointest Oncol 2024; 16(5): 1773-1786 [PMID: 38764839 DOI: 10.4251/wjgo.v16.i5.1773]
42
"This study is well designed." 
Man ZR, Gong XK, Qu KL, Pang Q, Wu BQ. Albumin–bilirubin grade as a predictor of survival in hepatocellular carcinoma patients with thrombocytopenia. World J Gastrointest Oncol 2024; 16(5): 1763-1772 [PMID: 38764822 DOI: 10.4251/wjgo.v16.i5.1763]
43
"This study is well designed. " 
Hoyos S, Posada-Moreno P, Guzman-Arango N, Chanci-Drago R, Chavez J, Andrés-Duarte A, Salazar-Ochoa S. Pancreatic neuroendocrine tumors: Are tumors smaller than 2 cm truly indolent? World J Gastrointest Oncol 2024; 16(5): 1756-1762 [PMID: 38764809 DOI: 10.4251/wjgo.v16.i5.1756]
44
"This study is well designed. " 
Zhang YY, Cai YW, Zhang X. Different lymph node staging systems for predicting the prognosis of colorectal neuroendocrine neoplasms. World J Gastrointest Oncol 2024; 16(5): 1745-1755 [PMID: 38764820 DOI: 10.4251/wjgo.v16.i5.1745]
45
"This study is well designed. " 
Zhou CM, Zhao SH. Evaluation of the value of combined detection of tumor markers CA724, carcinoembryonic antigen, CA242, and CA19-9 in gastric cancer. World J Gastrointest Oncol 2024; 16(5): 1737-1744 [PMID: 38764828 DOI: 10.4251/wjgo.v16.i5.1737]
46
"This review article is well written, and is informative for journal readers." 
Liu YY, Wu DK, Chen JB, Tang YM, Jiang F. Advances in the study of gastric organoids as disease models. World J Gastrointest Oncol 2024; 16(5): 1725-1736 [PMID: 38764838 DOI: 10.4251/wjgo.v16.i5.1725]
47
"This review article is well written, and is informative for journal readers. " 
Sánchez-Ramírez D, Mendoza-Rodríguez MG, Alemán OR, Candanedo-González FA, Rodríguez-Sosa M, Montesinos-Montesinos JJ, Salcedo M, Brito-Toledo I, Vaca-Paniagua F, Terrazas LI. Impact of STAT-signaling pathway on cancer-associated fibroblasts in colorectal cancer and its role in immunosuppression. World J Gastrointest Oncol 2024; 16(5): 1705-1724 [PMID: 38764833 DOI: 10.4251/wjgo.v16.i5.1705]
48
"This review article is well written, and is informative for journal readers." 
Nie SC, Jing YH, Lu L, Ren SS, Ji G, Xu HC. Mechanisms of myeloid-derived suppressor cell-mediated immunosuppression in colorectal cancer and related therapies. World J Gastrointest Oncol 2024; 16(5): 1690-1704 [PMID: 38764816 DOI: 10.4251/wjgo.v16.i5.1690]
49
"This document is indicative for journal readers. " 
Rozani S, Lykoudis PM. Overcoming geographical and socioeconomic limitations in colorectal cancer screening. World J Gastrointest Oncol 2024; 16(5): 1683-1689 [PMID: 38764845 DOI: 10.4251/wjgo.v16.i5.1683]
50
"This document is indicative for journal readers. " 
Khawkhiaw K, Panaampon J, Imemkamon T, Saengboonmee C. Interleukin-1β: Friend or foe for gastrointestinal cancers. World J Gastrointest Oncol 2024; 16(5): 1676-1682 [PMID: 38764841 DOI: 10.4251/wjgo.v16.i5.1676]