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1
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"The article is very interesting because it presents a minimally invasive spondylectomy for metastasis in the cervical spine. Minimally invasive cervical spondylectomy with tubular retractor is the most gentle on the surrounding structures - soft tissues, nerve roots and paraspinal muscles. It should be noted that it is a metastasis of follicular carcinoma of the thyroid gland with subsequent intake of iodine131, which further contributes to a significant suppression of residual tumor cells."
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He LM, Ma X, Chen C, Zhang HY. Treatment of cervical spine metastasis with minimally invasive cervical spondylectomy: A case report and literature review . World J Clin Cases 2021; 9(3): 644-650
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2
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"This is an interesting article."
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Bacharaki D, Diamandopoulos A. Emperor’s syndrome in the COVID-19 era: Time for patient-centered nephrology? World J Nephrol 2021; 10(1): 1-7
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3
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"The article is well written and may be of scientific interest in near future. However, one major concern regarding this paper is the absence of loading control in western-blot data, which might influenced the result and the conclusion of the study."
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Denner DR, Udan-Johns ML, Nichols MR. Inhibition of matrix metalloproteinase-9 secretion by dimethyl sulfoxide and cyclic adenosine monophosphate in human monocytes. World J Biol Chem 2021; 12(1): 1-14
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4
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"This type of article is a good resource for pushing practice in presence of social and medical stress rather than withheld clinical service that may be associated with high morbidity and mortality.
Actually this topic should be generalized to all specialties that have medical emergency e.g. coronary, surgery ...etc.
"
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Bacharaki D, Diamandopoulos A. Emperor’s syndrome in the COVID-19 era: Time for patient-centered nephrology? World J Nephrol 2021; 10(1): 1-7
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5
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" The current study demonstrated that ferroptosis is involved in endothelial dysfunction for the first time, and p53-xCT-GSH axis activation plays a crucial role in endothelial cell ferroptosis and endothelial dysfunction. It is an Interesting study. I have one comment: Does Ferroptosis inhibitor attenuates ferroptosis by inhibiting p53-xCT-GSH axis? "
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Luo EF, Li HX, Qin YH, Qiao Y, Yan GL, Yao YY, Li LQ, Hou JT, Tang CC, Wang D. Role of ferroptosis in the process of diabetes-induced endothelial dysfunction. World J Diabetes 2021; 12(2): 124-137
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6
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" It is an interesting meta-analysis which showed telemedicine interventions could significantly improve HbA1c, health outcomes as well as quality of life scores. Diabetes is a chronic metabolic disease and education is an important part in all stage of diabetic therapy. Good telemedicine intervention could improve patients' compliance and sure to effectively improve HbA1c and thus other related heath outcome. More importantly, it is a very economic way to help patients' to control their blood sugar."
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De Groot J, Wu D, Flynn D, Robertson D, Grant G, Sun J. Efficacy of telemedicine on glycaemic control in patients with type 2 diabetes: A meta-analysis. World J Diabetes 2021; 12(2): 170-197
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7
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"This narrative review describes the sarcopenia, frailty, and cachexia in heart failure patients very concisely showing a table of definitions. I think more detailed description of the relationship between muscle dysfunction and cardiac function and the effects of cardiac rehabilitation would make this review more complete. "
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Beltrami M, Fumagalli C, Milli M. Frailty, sarcopenia and cachexia in heart failure patients: Different clinical entities of the same painting. World J Cardiol 2021; 13(1): 1-10
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8
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"The article entitled “Inhibition of matrix metalloproteinase-9 secretion by dimethyl sulfoxide and cyclic adenosine monophosphate in human monocytes” by Darcy R Denner, Maria LD Udan-Johns, Michael R Nichols describes the stimulation of matrix metalloproteinase-9 (MMP-9) and tumor necrosis factor α (TNFα) secretion from human monocyte cells by lipopolysaccharide, and the inhibition of this process by dimethyl sulfoxide and increased intracellular levels of 3',5'-cyclic adenosine monophosphate. The authors claimed that the experimental findings demonstrated that dimethyl sulfoxide concentration must be carefully controlled in inflammatory studies, that MMP-9 secretion occurred downstream from TNFα secretion and that the two processes were distinct, and that TNFα is an integral component of the pathway leading to MMP-9 secretion. To track the scientific quality of the paper, I give the following comments.
1 Ethics: Does the ethical approval form provided by the author meet the requirements?
N/A. The authors used cultured cells but not animals or human samples.
2 Methods: Is the experimental method effective? Can it be repeated by fellow researchers (according to adequate textual/citation content presented)?
Yes. The methods are detailed introduced and can be repeated..
3 Results: Are the results true and authentic? Is the theory or hypothesis of universal significance validated or partially validated?
Yes. The results are true and authentic. The hypothesis of universal significance is partially validated.
4 Figures and tables: Does the author provide perfect tables, line charts and/or graphs? Or, does the author provide figures and tables that are confusing, poorly constructed and/or not well-annotated?
One of my concerns is that the loading control for immunoblot analysis, such as beta-actin and or GAPDH is missing.
5 Biostatistics: Does the author provide perfect biostatistics data? Or, does the author provide tables and line charts that have mistakes in the data?
Yes.
6 References: Does the author scientifically and reasonably cite the latest references which are important in this field and related to the scientific problems and research hypotheses addressed in the study? Or, does the author self-cite, omit, mis-cite and/or over-cite references?
Yes.
7 Language: Does the language in article correctly, clearly and concisely express the information? Or, does the article have multiple grammatical and spelling mistakes?
Yes.
8 Caveats or drawbacks: What are the caveats or drawbacks for the results?
A loading control should be examined. The levels of the target proteins should be subjected to normalization using the loading control.
"
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Denner DR, Udan-Johns ML, Nichols MR. Inhibition of matrix metalloproteinase-9 secretion by dimethyl sulfoxide and cyclic adenosine monophosphate in human monocytes. World J Biol Chem 2021; 12(1): 1-14
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9
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"This systematic review is well design. It based on randomized controlled trials was conducted to appraise the benefit of chemotherapy-assisted addition of COX-2 for advanced NSCLC. The method was effective.
By meta-analysis 12 trials, they concluded that COX-2 inhibitor combined with chemotherapy increased total effective rate of advanced NSCLC with the possible increased risk of blood toxicity and cardiovascular events and had no effect on survival index. This study can provide reference value for the application of COX-2 in the treatment of lung cancer."
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Xu YQ, Long X, Han M, Huang MQ, Lu JF, Sun XD, Han W. Clinical benefit of COX-2 inhibitors in the adjuvant chemotherapy of advanced non-small cell lung cancer: A systematic review and meta-analysis. World J Clin Cases 2021; 9(3): 581-601
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10
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"As we all are pretty much aware that 10-33 % of Open Angle Glaucoma patients have mutations in several genes, which are mainly myocilin, optineurin, and CYP1B1. A lot of genetic evaluation studies are being done in the recent past 5 years at a much larger-scale to discover more common genetic risk factors for POAG and PACG . These studies had lead the frontiers to know many more risk factors which include changes in the DNA sequences (near or in the genes such as caveolin 1 and 2 (CAV1/CAV2), CDKN2B antisense RNA, TMCO1, SIX1/SIX6, and LRP12/ZFPM2 genes) or actual loss of DNA (TBK1 and GALC), and various genes have been indicated. So to know how and why all these genes have the potential of developing POAG is a major concern for all the Ophthalmologists and researchers.
Primary congenital or juvenile open angle glaucoma (PCOAG) is the most common childhood glaucoma affecting children from birth to age 3 -30 Years and is a main cause of irreversible blindness in this young age-group. Mutations in the CYP1B1 gene have been found to cause PCG in children worldwide and are the dominant genetic cause for glaucoma in children in the Middle East and central Europe.
So. the authors had presented quite an extraordinary case with a very uncommon genetic mutation in the OLFM2 and SIX6 genes in a case of Juvenile open angle glaucoma. This will further encourage the researchers involved in the various studies to co-relate genetic mutations associated with Glaucoma and to develop appropriate genetic - therapy for primary glaucoma patients."
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Yang X, Sun NN, Zhao ZN, He SX, Zhang M, Zhang DD, Yu XW, Zhang JM, Fan ZG. Coinheritance of OLFM2 and SIX6 variants in a Chinese family with juvenile-onset primary open-angle glaucoma: A case report. World J Clin Cases 2021; 9(3): 697-706
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11
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"Nice work, with very interesting data about liver injury and covid 19. May be more have to be writen about some prognostic factors related to outcome form covid and hepatic involvment. Some additional data obout the treatment of this liver abnosramlities should be add."
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Han MW, Wang M, Xu MY, Qi WP, Wang P, Xi D. Clinical features and potential mechanism of coronavirus disease 2019-associated liver injury. World J Clin Cases 2021; 9(3): 528-539
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12
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"Thank you for the work. A small comment: instead of looking at the impact of sutured anastomoses on local ischemia, it would be more helpful to compare with any of ischemic preconditionings or preventive treatments when a stapled bowel anastomosis is not applied. Hope to see extended studies are underway."
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Hanberg P, Bue M, Thomassen M, Løve US, Kipp JO, Harlev C, Petersen E, Søballe K, Stilling M. Influence of anastomoses on intestine ischemia and cefuroxime concentrations: Evaluated in the ileum and colon in a porcine model. World J Gastrointest Pathophysiol 2021; 12(1): 1-13
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13
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"Ethics are not relevant to this paper.
Methods of literature review have not been defined.
The conclusions of the paper are evidence based and appear to be true and authentic. The topic chosen is clinically relevant and interesting.
Biostatistics and tables are not applicable to this paper.
References are appropriate and properly formatted
2 small language mistakes noted
No caveats"
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Khalaf M, Castell D, Elias PS. Spectrum of esophageal motility disorders in patients with liver cirrhosis. World J Hepatol 2020; 12(12): 1158-1167
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14
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"Ethics are not relevant to the paper since its a review article
Methods of literature review are not defined in detail
Figures are correct and representative
Biostatistics are not applicable
References are up to date and formatted properly
Language is polished and free of mistakes.
No obvious caveats"
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Ahn KS, Kang KJ. Molecular heterogeneity in intrahepatic cholangiocarcinoma. World J Hepatol 2020; 12(12): 1148-1157
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15
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"Every aspects this research article is well done."
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Hanberg P, Bue M, Thomassen M, Løve US, Kipp JO, Harlev C, Petersen E, Søballe K, Stilling M. Influence of anastomoses on intestine ischemia and cefuroxime concentrations: Evaluated in the ileum and colon in a porcine model. World J Gastrointest Pathophysiol 2021; 12(1): 1-13
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16
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"Although the topic is of potential (although limited) interest in this paper it is not possible to evaluate the true relevance of the results and conclusions as essential controls are absent. In fact it is unknown whether a 48-72h treatment with the compounds can have an effect on cell viability/proliferation causing a relevant alterations of target release for causes that might not be associated to a specific signal transduction pathway. Standard cell proliferation/cell damage assays could have helped to answer this. Indeed I cannot evaluate whether the release is associated to altered proliferation or some type of cell damage other than a specific effect on the signal transduction machinery as the authors suggest. It is not even clear if the same number of cells has been analyzed lacking any loading control. The authors only report that they have centrifuged the cells. The authors in fact assume that no effect other than on the direct signal machinery associated to TNFa and MMP9 is involved but after 24 to 72hr treatment they need to provide appropriate controls to secure the real value of the data presented.
Research motivation and research objective sections contain essentially the same sentences whereas they should express different concepts.
"
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Denner DR, Udan-Johns ML, Nichols MR. Inhibition of matrix metalloproteinase-9 secretion by dimethyl sulfoxide and cyclic adenosine monophosphate in human monocytes. World J Biol Chem 2021; 12(1): 1-14
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17
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"I reviewed this interesting case report with 3 recurrences of Takotsubo syndrome, and I have some comments to make related to the ECG aspect of the patient:
Please explain the electrical stimulation artifact before the P wave in Figure 1A and B.
Does the patient have a single or a double -chamber pacemaker ?
Please explain the stimulation artifact on the T wave in Figure 1 B.
Could the decrease in the LV ejection fraction be explained by a pacemaker malfunction? Or by asynchronous stimulation of the right ventricle?"
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Wu HY, Cheng G, Liang L, Cao YW. Recurrent Takotsubo cardiomyopathy triggered by emotionally stressful events: A case report. World J Clin Cases 2021; 9(3): 677-684
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18
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"Congratulation to the authors for this excellent paper with high Expertise, very good Standards in diagnosis, indication, surgery, documentation of M+M and Follow up, obviously in all pancreatic patietns of your Group. Your Definition of the criteria für PPDR are clear, and your Change of operatve procedures after Evaluation of the results of previous types of surgery applied is a sign of high scientific knowledge. Your conclusion should be accepted by the Major pancreatic surgeons, eg. organized in "ESPAC".
The reasons for giving this Statement are as follows:
Your Patient number is very high as well as your Expertise in treating patients with pancreatic disease either conservatively of surgically. Obviously the indications for conservative vs. surgical Treatment are made at the interdisciplinary Level (although a Gastroenterologist is not among your coauthors). Your radiologist are very well equipped and precise in their daignosis (83/84 of the diagnoses made by radiology, endoscopy, neddle biopsy/pathology were correct). In your introduction you mention, that the disease CDDW is rare, implicating, that the patients should be monitored/treated in spezialized Centers. Your experience led to the Change of the operative procedures and the clear Definition for the indication of PPDR in CDDW. - As you are a top Institution in Moscow/Russia, you consequently have the knowledge and the means not only to perform high Quality surgery, but also to document your results adequately. You are using the optimal paramenters for Quality of life ("Itzbicky"), complications (M+M, Clavien-Dindo) and Fisdtula grades. Your Long term follow up up to 188 months is also a high Quality sign of your Group. Congratulations that you convinced so many of your male pts. to stop drinking alcohol postoperatively. Regarding the excellent Long term functional results of PPDR vs. PD (and more expressed after Duodenim Preserving surgery or even Drainage) are convincing and very well documented, also in the Tables. A remark to table 6: The hospital stay after PPDR is significantly longer than after PD (p=0.03).; in the discussion you make sthe Statement that it was not significanly different. The discussion respects all questions and the reports of other Groups. The Limitation "retrospective" and observational is correct. But a prospective correlatice Trial e.g. comparing PD vs. PPDR is nearly impossible to conduct, and regarding the extremely cklear Advantage of PPDR vs. PD not justified."
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Egorov V, Petrov R, Schegolev A, Dubova E, Vankovich A, Kondratyev E, Dobriakov A, Kalinin D, Schvetz N, Poputchikova E. Pancreas-preserving duodenal resections vs pancreatoduodenectomy for groove pancreatitis. Should we revisit treatment algorithm for groove pancreatitis? World J Gastrointest Surg 2021; 13(1): 30-49
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19
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"The present article appears to be credible, the methods correct an the conclusions sound.
Figure 1: I would have used orizontal layout for the first column too. The vertical layout implies the need to rotate the head to read the table. I feel unconfortable to do this.
Biostatistics appears to be adequate
References: appear to be adequate
Language: appears to be adequate
"
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Saha S, Saha S. Epidemiological burden of parents being the index cases of COVID-19 infected children. World J Methodol 2021; 11(1): 1-14
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20
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" The author scientifically and reasonably cited the latest references to discusses the risks and benefits of a fever on the host response, focusing on the effects of a fever on viral replication and host response, and the detrimental effect on the host. In this review, the author illustrated the effect of a fever in viral infections and validated the theory clearly which have very important significance. "
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Belon L, Skidmore P, Mehra R, Walter E. Effect of a fever in viral infections — the ‘Goldilocks’ phenomenon? World J Clin Cases 2021; 9(2): 296-307
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21
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"good"
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Chen M, Fang Y, Yang Y, He PJ, Cheng L, Wu HT. Circulating immune parameters-based nomogram for predicting malignancy in laryngeal neoplasm. World J Clin Cases 2021; 9(3): 540-551
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22
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"good paper"
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Gładyś A, Kozak S, Wdowiak K, Winder M, Chudek J. Infectious complications during immunochemotherapy of post-transplantation lymphoproliferative disease–can we decrease the risk? Two case reports and review of literature. World J Clin Cases 2021; 9(3): 748-757
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23
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" Ethics: Does the ethical approval form provided by the author meet the requirements?
Not applicable.
2 Methods: Is the experimental method effective? Can it be repeated by fellow researchers (according to adequate textual/citation content presented)?
Yes, in my opinion the experimental method is effective and can be repeated.
3 Results: Are the results true and authentic? Is the theory or hypothesis of universal significance validated or partially validated?
In my opinion results are true and authentic.
4 Figures and tables: Does the author provide perfect tables, line charts and/or graphs? Or, does the author provide figures and tables that are confusing, poorly constructed and/or not well-annotated?
The only table provided is good.
5 Biostatistics: Does the author provide perfect biostatistics data? Or, does the author provide tables and line charts that have mistakes in the data?
The only table provided is correct.
6 References: Does the author scientifically and reasonably cite the latest references which are important in this field and related to the scientific problems and research hypotheses addressed in the study? Or, does the author self-cite, omit, mis-cite and/or over-cite references?
References are correct.
7 Language: Does the language in article correctly, clearly and concisely express the information? Or, does the article have multiple grammatical and spelling mistakes?
The language in the article clearly and concisely express the information. The article does not have multiple grammatical and spelling mistakes.
8 Caveats or drawbacks: What are the caveats or drawbacks for the results? None
"
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Henriquez I, Spratt D, Gómez-Iturriaga A, Abuchaibe O, Couñago F. Nonmetastatic castration-resistant prostate cancer: Novel agents to treat a lethal disease. World J Clin Oncol 2021; 12(1): 6-12
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24
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"In this paper the authors have investigated the regulation mechanisms of the secretion of MMP-9 and TNFα by DMSO and cAMP in human monocytes, suggesting that DMSO inhibits the MMP-9 release, but not of cAMP, whereas cAMP inhibits both MMP-9 and TNFα at different monocyte cell exposure time points.
The paper is readily intelligible because the experimental design is well-constructed, clear and well described with figures and tables appropriate to the subject matter. The scientific background and aims are clearly explained. The methodology seems to be appropriate to the research field and the conclusions logically follow from the results. The references are pertinent.
Although this manuscript isn’t very original and innovative, since other papers were already published about this topic, however it’s very interesting.
No endogen control was used by authors to performe the experiments (Western blots, SDS-PAGE)."
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Denner DR, Udan-Johns ML, Nichols MR. Inhibition of matrix metalloproteinase-9 secretion by dimethyl sulfoxide and cyclic adenosine monophosphate in human monocytes. World J Biol Chem 2021; 12(1): 1-14
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25
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" Ethics: Does the ethical approval form provided by the author meet the requirements?
Not applicable.
2 Methods: Is the experimental method effective? Can it be repeated by fellow researchers (according to adequate textual/citation content presented)?
Yes, in my opinion the experimental method is effective and can be repeated.
3 Results: Are the results true and authentic? Is the theory or hypothesis of universal significance validated or partially validated?
In my opinion results are true and authentic.
4 Figures and tables: Does the author provide perfect tables, line charts and/or graphs? Or, does the author provide figures and tables that are confusing, poorly constructed and/or not well-annotated?
The tables provided are good.
5 Biostatistics: Does the author provide perfect biostatistics data? Or, does the author provide tables and line charts that have mistakes in the data?
The tables provided are correct.
6 References: Does the author scientifically and reasonably cite the latest references which are important in this field and related to the scientific problems and research hypotheses addressed in the study? Or, does the author self-cite, omit, mis-cite and/or over-cite references?
References are correct.
7 Language: Does the language in article correctly, clearly and concisely express the information? Or, does the article have multiple grammatical and spelling mistakes?
The language in the article clearly and concisely express the information. The article does not have multiple grammatical and spelling mistakes.
8 Caveats or drawbacks: What are the caveats or drawbacks for the results? None
"
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Valencia GA, Neciosup S, Gómez HL, Benites MDP, Falcón S, Moron D, Veliz K, Maldonado M, Auqui R. Adaptation of international coronavirus disease 2019 and breast cancer guidelines to local context. World J Clin Oncol 2021; 12(1): 31-42
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26
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"1- Ethics: Due tor retrospective nature of study, was exempted from ethics approval.
2- Methods: It was a retrospective study, no control group , with passive follow up of patients after FMT. It would be more meaningful if all patients with FMT were followed for skin lesions after FMT.
3- Results: As an extrapolatory study, the results encourage investigators to do a controlled prospective study.
6- References: Ok
7- Language: OK
8-: The main drawback is retrospective uncontrolled passive nature of study.
4- Figures and tables are OK.
5- Biostatistics: Due to lack of a control group, most comparisons are not very meaningful or conclusive."
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Snyder AM, Abbott J, Jensen MK, Secrest AM. Fecal microbiota transplant and dermatologic disorders: A retrospective cohort study assessing the gut microbiome’s role in skin disease. World J Dermatol 2021; 9(1): 1-10
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27
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"This is a good review."
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Gvetadze SR, Ilkaev KD. Lingual lymph nodes: Anatomy, clinical considerations, and oncological significance. World J Clin Oncol 2020; 11(6): 337-347
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28
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"This is a good literature review."
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Pitoia F, Smulever A. Active surveillance in low risk papillary thyroid carcinoma. World J Clin Oncol 2020; 11(6): 320-336
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29
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"This is an opinion review very interesting."
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Suttorp M, Metzler M, Millot F. Horn of plenty: Value of the international registry for pediatric chronic myeloid leukemia. World J Clin Oncol 2020; 11(6): 308-319
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30
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"This is an informative and well-written review."
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Szczepanek J. Role of microRNA dysregulation in childhood acute leukemias: Diagnostics, monitoring and therapeutics: A comprehensive review. World J Clin Oncol 2020; 11(6): 348-369
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31
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"This is an interesting and well-written review."
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Zhao D, Xie B, Yang Y, Yan P, Liang SN, Lin Q. Progress in immunotherapy for small cell lung cancer. World J Clin Oncol 2020; 11(6): 370-377
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32
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"It is a good and well-written study."
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Panyavaranant P, Manchana T. Preoperative markers for the prediction of high-risk features in endometrial cancer. World J Clin Oncol 2020; 11(6): 378-388
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33
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"This is an interesting study."
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Blank AT, Larson BM, Shaw S, Wakefield CJ, King T, Jones KB, Randall RL. National Comprehensive Cancer Network guidelines compliance of a sarcoma service: A retrospective review. World J Clin Oncol 2020; 11(6): 389-396
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34
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"This is an interesting study."
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Fiorentini G, Sarti D, Patriti A, Eugeni E, Guerra F, Masedu F, Mackay AR, Guadagni S. Immune response activation following hyperthermic intraperitoneal chemotherapy for peritoneal metastases: A pilot study. World J Clin Oncol 2020; 11(6): 397-404
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35
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"This is a good case report."
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Kawahigashi T, Kitagawa I, Tanaka E. Angioimmunoblastic T-cell lymphoma accompanied by pure red cell aplasia: A case report. World J Clin Oncol 2020; 11(6): 405-411
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36
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"This is a good systematic review."
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Valencia GA, Neciosup S, Gómez HL, Benites MDP, Falcón S, Moron D, Veliz K, Maldonado M, Auqui R. Adaptation of international coronavirus disease 2019 and breast cancer guidelines to local context. World J Clin Oncol 2021; 12(1): 31-42
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37
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"This is an interesting study."
-
Mehdipour P, Javan F, Jouibari MF, Khaleghi M, Mehrazin M. Evolutionary model of brain tumor circulating cells: Cellular galaxy. World J Clin Oncol 2021; 12(1): 13-30
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38
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"This is a very good, informative and well-written editorial."
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Henriquez I, Spratt D, Gómez-Iturriaga A, Abuchaibe O, Couñago F. Nonmetastatic castration-resistant prostate cancer: Novel agents to treat a lethal disease. World J Clin Oncol 2021; 12(1): 6-12
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39
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"It is a good editorial."
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Barros JM, Rizzo MM, Chiozza JO, Couñago F. Is there a place for optimizing thoracic radiotherapy in limited-stage small cell lung cancer after twenty years? World J Clin Oncol 2021; 12(1): 1-5
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40
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"interesting study...small sample size though"
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Paul R, Sathe P, Kumar RS, Prasad S, Aleem M, Sakhalvalkar P. Multicentered prospective investigator initiated study to evaluate the clinical outcomes with extracorporeal cytokine adsorption device (CytoSorb®) in patients with sepsis and septic shock. World J Crit Care Med 2021; 10(1): 22-34
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41
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"Difficult to follow at times"
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Omar AS, Hanoura S, Shouman Y, Sivadasan PC, Sudarsanan S, Osman H, Pattath AR, Singh R, AlKhulaifi A. Intensive care outcome of left main stem disease surgery: A single center three years’ experience. World J Crit Care Med 2021; 10(1): 12-21
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42
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"Great article....well written"
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Kichloo A, Kumar A, Amir R, Aljadah M, Farooqi N, Albosta M, Singh J, Jamal S, El-Amir Z, Kichloo A, Lone N. Utilization of extracorporeal membrane oxygenation during the COVID-19 pandemic. World J Crit Care Med 2021; 10(1): 1-11
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43
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"the title of the manuscript does not reflect the depicted topics within the article especially the method of water insufflation colonoscopy which could be an attractive and appealing to readers."
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Hayman CV, Vyas D. Screening colonoscopy: The present and the future. World J Gastroenterol 2021; 27(3): 233-239
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44
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"I read with interest the article by Javier Briceño et al "Back-table surgery pancreas allograft for transplantation: Implications in complications" in which the authors made a mini-review about this topic
I want to congratulate the authors for such an interesting paper.
This is a nice basic paper, with all the most remarkable information about bench table surgery in pancreas transplantation with some tips to take in mind"
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Briceño J, Sánchez-Hidalgo JM, Arjona-Sanchez A. Back-table surgery pancreas allograft for transplantation: Implications in complications. World J Transplant 2021; 11(1): 1-6
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45
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"The manuscript fulfills the scientific criteria for being published in World Journal of Cardiology. It is a novel case report study which add further evidence of myasthenic crisis induced Takotsubo cardiomyopathy."
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Kuo Y, Ottens TH, van der Bilt I, Keunen RW, Akin S. Myasthenic crisis-induced Takotsubo cardiomyopathy in an elderly man: A case report of an underestimated but deadly combination. World J Cardiol 2021; 13(1): 21-27
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46
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"The review entitled “Frailty, sarcopenia and cachexia in heart failure patients: different clinical entities of the same painting” underlines the negative impact of cardiac cachexia, sarcopenia and frailty on outcome of patients with heart failure. It is a very interesting paper summarizing and discussing all evidences regarding the three different phenotypes that is possible to diagnose in older adults with heart failure."
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Beltrami M, Fumagalli C, Milli M. Frailty, sarcopenia and cachexia in heart failure patients: Different clinical entities of the same painting. World J Cardiol 2021; 13(1): 1-10
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47
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"1. Ethics: Does the ethical approval form provided by the author meet the requirements? Yes
2 Methods: Is the experimental method effective? Can it be repeated by fellow researchers (according to adequate textual/citation content presented)? Yes
3 Results: Are the results true and authentic? Is the theory or hypothesis of universal significance validated or partially validated? validated
4 Figures and tables: Does the author provide perfect tables, line charts and/or graphs? Or, does the author provide figures and tables that are confusing, poorly constructed and/or not well-annotated?
The tables are rather descriptive. These tables need to be more concisely described.
5 Biostatistics: Does the author provide perfect biostatistics data? Or, does the author provide tables and line charts that have mistakes in the data? χ2/Z/t value doesn’t need to be included. Even though age and sex were not statistically significant in the univariate analysis, it would be better to include these variables in the multivariate analysis.
6 References: Does the author scientifically and reasonably cite the latest references which are important in this field and related to the scientific problems and research hypotheses addressed in the study? Or, does the author self-cite, omit, mis-cite and/or over-cite references? Nothing particular
7 Language: Does the language in article correctly, clearly and concisely express the information? Or, does the article have multiple grammatical and spelling mistakes? Although it needs some edits, it is generally OK for the readers.
8 Caveats or drawbacks: What are the caveats or drawbacks for the results? Retrospective analysis and insufficient information for inclusion and selection process for healthy controls.
"
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Huang CZ, Zhang J, Zhang L, Yu CH, Mo Y, Mo LY. Serum vitamin D and vitamin-D-binding protein levels in children with chronic hepatitis B. World J Gastroenterol 2021; 27(3): 255-266
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48
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"none"
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Henriquez I, Spratt D, Gómez-Iturriaga A, Abuchaibe O, Couñago F. Nonmetastatic castration-resistant prostate cancer: Novel agents to treat a lethal disease. World J Clin Oncol 2021; 12(1): 6-12
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49
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"Good"
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Briceño J, Sánchez-Hidalgo JM, Arjona-Sanchez A. Back-table surgery pancreas allograft for transplantation: Implications in complications. World J Transplant 2021; 11(1): 1-6
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50
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-
"The paper is interesting. Experimental methods are effective and the hypothesis is well validated by the results. Figures are clearly presented and annotated.
However, in the paper it is not clear why in the abstract, in the highlight, in the introduction and in the most part of the discussion the authors speak about only of the LPS-induced MMP-9 secretion in THP-1 human monocytes and not also of Amyloid-β peptide-induced matrix-metalloproteinase-9 secretion.
Instead, in my opinion the most interesting data is the MMP-9 induction by the Amyloid-β peptide (Figure 7), even if the data is not totally new. It can have more importance from the clinical point of view.
Moreover, a better explaining of the implication of the study findings and of the MMP-9 role in the Alzheimer’s disease and in other related diseases would have been necessary.
"
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Denner DR, Udan-Johns ML, Nichols MR. Inhibition of matrix metalloproteinase-9 secretion by dimethyl sulfoxide and cyclic adenosine monophosphate in human monocytes. World J Biol Chem 2021; 12(1): 1-14
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