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1
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"This is a good paper for perianal fistula. There have been cases of HIV infection with anal fistulas, so we would also like you to get an HIV test."
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Pacheco T, Monteiro S, Barros L, Silva J. Perianal disease in inflammatory bowel disease: Broadening treatment and surveillance strategies for anal cancer. World J Gastroenterol 2024; 30(28): 3373-3385 [DOI: 10.3748/wjg.v30.i28.3373]
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2
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"Thank you for the opportunity to review this interesting narrative review on the gut microbiota and inflammatory diseases. The authors should be commended for their comprehensive synthesis of the current evidence on the complex relationship between gut microbiome composition and inflammatory diseases.
Upon reviewing the manuscript, I would like to highlight several aspects that require consideration:
1- Underscoring the focus on perinatal environment and some microbiota disruptors, ensuring alignment with the content
2- Language Precision: Some linguistic inaccuracies detract from the manuscript's clarity
3- Reference Enrichment
4- Conclusion Enhancement
In a detailed analysis, here are the remarks and comments:
- The authors should discuss the significant impact of delivery mode (vaginal delivery versus cesarean section) and breastfeeding practices (exclusive versus non-exclusive, duration) on the development of the gut microbiome.
o Vandenplas Y, Carnielli VP, Ksiazyk J, et al. Factors affecting early-life intestinal microbiota development. Nutrition. 2020;78:110812. doi:10.1016/j.nut.2020.110812
- Additionally, the authors should elaborate on the implications of antibiotic use and the potential effects of antacids (such as proton pump inhibitors) on the dysbiosis of intestinal flora.
o Weersma RK, Zhernakova A, Fu J. Interaction between drugs and the gut microbiome. Gut. 2020;69(8):1510-1519. doi:10.1136/gutjnl-2019-320204
o Fishbein SRS, Mahmud B, Dantas G. Antibiotic perturbations to the gut microbiome. Nat Rev Microbiol. 2023;21(12):772-788. doi:10.1038/s41579-023-00933-y
o Zhang J, Zhang C, Zhang Q, et al. Meta-analysis of the effects of proton pump inhibitors on the human gut microbiota. BMC Microbiol. 2023;23(1):171. Published 2023 Jun 19. doi:10.1186/s12866-023-02895-w
- Conversely, the protective effects of certain viral and parasitic infections warrant a dedicated section.
o Sardinha-Silva A, Alves-Ferreira EVC, Grigg ME. Intestinal immune responses to commensal and pathogenic protozoa. Front Immunol. 2022;13:963723. Published 2022 Sep 16. doi:10.3389/fimmu.2022.963723
- Autoimmune diseases, which involve acquired immunity, should be addressed in a separate section, alongside autoinflammatory conditions that pertain to innate immunity.
o Xu Q, Ni JJ, Han BX, et al. Causal Relationship Between Gut Microbiota and Autoimmune Diseases: A Two-Sample Mendelian Randomization Study. Front Immunol. 2022;12:746998. Published 2022 Jan 24. doi:10.3389/fimmu.2021.746998
o Christovich A, Luo XM. Gut Microbiota, Leaky Gut, and Autoimmune Diseases. Front Immunol. 2022;13:946248. Published 2022 Jun 27. doi:10.3389/fimmu.2022.946248
o Shao T, Hsu R, Rafizadeh DL, et al. The gut ecosystem and immune tolerance. J Autoimmun. 2023;141:103114. doi:10.1016/j.jaut.2023.103114
- In the context of gut microbiota modulation, synbiotics should be included among other therapeutic interventions.
o Li HY, Zhou DD, Gan RY, et al. Effects and Mechanisms of Probiotics, Prebiotics, Synbiotics, and Postbiotics on Metabolic Diseases Targeting Gut Microbiota: A Narrative Review. Nutrients. 2021;13(9):3211. Published 2021 Sep 15. doi:10.3390/nu13093211
- Some key terms need to be clearly defined, such as "leaky gut.", synbiotics…etc
- The title of Figure 6 contains an error; it should refer to the "Gut–Liver axis" instead of the "Gut–Lung axis."
- The conclusion should be condensed for clarity and brevity.
In summary, this is a well-written narrative review that provides a comprehensive overview of the gut microbiota and its role in inflammatory diseases. With some minor revisions to address the points mentioned above, the manuscript will be a valuable contribution to the field.
"
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Marik A, Biswas S, Banerjee ER. Exploring the relationship between gut microbial ecology and inflammatory disease: An insight into health and immune function. World J Immunol 2024; 14(1): 96209 [DOI: 10.5411/wji.v14.i1.96209]
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3
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"Completely agree with the author'e editorial. EU-Guided Biliary drainage is an excellent alternative for cases where ERCP is incapable of biliary drainage (stenting). Excellent approach and meta-analysis..."
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Wu SZ. Endoscopic ultrasound-guided biliary drainage using electrocautery-enhanced lumen-apposing metal stent for malignant biliary obstruction: A promising procedure. World J Clin Cases 2024; 12(24): 5859-5862 [DOI: 10.12998/wjcc.v12.i24.5859]
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4
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"This is an excellent intervention that could as well be studied in patients with other cancers. EG prostate cancer which is the number 1 cancer in the world for men. Excellent approach and knowledge is up-to-date..."
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Xin YY, Zhao D. Impact of web-based positive psychological intervention on emotions, psychological capital, and quality of life in gastric cancer patients on chemotherapy. World J Clin Cases 2024; 12(26): 5877-5884 [DOI: 10.12998/wjcc.v12.i26.5877]
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5
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"Ethics: The ethical approval form is provided by the authors and meets the requirements.
Methods: The experimental method is effective. It be repeated by fellow researchers (according to adequate textual/citation content presented).
Results: The results look true and authentic. The theory or hypothesis is of universal significance. Due to a case report, it is not validated. Only multicentric studies on the subject can validate the theory.
Figures and tables: The authors provide perfect tables, line charts and/or graphs.
Biostatistics: This is a case report without biostatistics.
References: The authors scientifically and reasonably cite the latest references which are important in this field and related to the scientific problems and research hypotheses addressed in the study.
Language: The language in the article correctly, clearly, and concisely express the information.
Caveats or drawbacks: Correctly written case report. I do not understand that this is the first case by clinical physician. All diagnoses, in all 5 patents were made postoperatively with immunohistochemical analysis. Also, more data should be displayed in the table of these 5 patients. Maybe some risk factors could be found, such as smoking or something else."
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Sun MQ, Guo LN, You Y, Qiu YY, He XD, Han XL. Sclerosing epithelioid fibrosarcoma of the pancreas: A case report. World J Clin Cases 2024; 12(26): 5983-5989 [DOI: 10.12998/wjcc.v12.i26.5983]
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6
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"
This multicentre study was conducted to determine the efficacy of a dual therapeutic regimen consisting of a combination of Vonoprazan and amoxicillin in Chinese patients with a confirmed diagnosis of Helicobacter pylori infection. The authors found that dual therapy lasting for 10 or 14 days including the administration of Vonoprazan, a strong inhibitor of stomach hydrochloric acid secretion combined with amoxicillin achieved higher eradication rates than the bismuth-based quadruple regimen with fewer side effects.
The results of this study rekindle the scientific interest in the role of amoxicillin-based dual treatment regimens with which eradication of Helicobacter pylori is expected to be simpler and with fewer side effects.
However, the results of this study should be confirmed by studies conducted in Europe to be accepted internationally. It is widely accepted that the characteristics of Asian patients may be different from those of European patients. The relatively small number of patients included should be pointed out.
Large multicentre studies should be carried out which will determine with certainty the duration and effectiveness of this treatment.
"
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Huang XP, Liu YJ, Lin SW, Shao YF, Qiu F, Qiu QW, Xu ZK, Chen JX, Chen LH, Lin ZQ, Dai WH, Zhang MQ, Jiang Q, Xiao ZQ, Cheng XX, Zhang XF, You WB, Chen W, Li LQ, Lin WX, Wang YF, Lai FJ, Chen LQ, Huang ZH, Zheng WQ, Wei JQ, Lin ZH. Vonoprazan-amoxicillin dual therapy for Helicobacter pylori eradication in Chinese population: A prospective, multicenter, randomized, two-stage study. World J Gastroenterol 2024; 30(27): 3304-3313 [DOI: 10.3748/wjg.v30.i27.3304]
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7
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"1 Ethics: Does the ethical approval form provided by the author meet the requirements?
N/A.
2 Methods: Is the experimental method effective? Can it be repeated by fellow researchers (according to adequate textual/citation content presented)?
YES.
3 Results: Are the results true and authentic? Is the theory or hypothesis of universal significance validated or partially validated?
YES.
4 Figures and tables: Does the author provide perfect tables, line charts and/or graphs? Or, does the author provide figures and tables that are confusing, poorly constructed and/or not well-annotated?
YES, Fitures and tables are perfect.
5 Biostatistics: Does the author provide perfect biostatistics data? Or, does the author provide tables and line charts that have mistakes in the data?
NA
6 References: Does the author scientifically and reasonably cite the latest references which are important in this field and related to the scientific problems and research hypotheses addressed in the study? Or, does the author self-cite, omit, mis-cite and/or over-cite references?
YES.
7 Language: Does the language in article correctly, clearly and concisely express the information? Or, does the article have multiple grammatical and spelling mistakes?
The language of the paper is correct
8 Caveats or drawbacks: What are the caveats or drawbacks for the results?
No.
"
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Tombesi P, Cutini A, Grasso V, Di Vece F, Politti U, Capatti E, Labb F, Petaccia S, Sartori S. Past, present, and future perspectives of ultrasound-guided ablation of liver tumors: Where could artificial intelligence lead interventional oncology? Artif Intell Cancer 2024; 5(1): 96690 [DOI: 10.35713/aic.v5.i1.96690]
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8
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"Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied."
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Moreno JC, Uson Junior PLS. Clear cell sarcoma of the pancreas, an unusual cancer with unusual metastatic site or unusual primary site? World J Clin Cases 2024; 12(25): 5653-5656 [DOI: 10.12998/wjcc.v12.i25.5653]
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9
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"Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied."
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Zhang Y, Cui YF. Severe acute pancreatitis complicated with intra-abdominal infection secondary to trauma: A case report. World J Clin Cases 2024; 12(25): 5821-5831 [DOI: 10.12998/wjcc.v12.i25.5821]
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10
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"Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied."
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Wishahi M, Kamal NM, Hedaya MS. Enhanced recovery after surgery: Progress in adapted pathways for implementation in standard and emerging surgical settings. World J Clin Cases 2024; 12(25): 5636-5641 [DOI: 10.12998/wjcc.v12.i25.5636]
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11
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"Ethics: The ethical approval form is provided by the authors and meets the requirements.
Methods: The experimental method is effective. It be repeated by fellow researchers (according to adequate textual/citation content presented).
Results: The results look true and authentic. The theory or hypothesis is of universal significance. Due to a case report, it is not validated. Only multicentric studies on the subject can validate the theory.
Figures and tables: The authors provide perfect tables, line charts and/or graphs.
Biostatistics: This is a case report without biostatistics.
References: The authors scientifically and reasonably cite the latest references which are important in this field and related to the scientific problems and research hypotheses addressed in the study.
Language: The language in the article correctly, clearly, and concisely express the information.
Caveats or drawbacks: Only three cases are described from the literature. Small amount of data are extracted from these case reports. Therefore, strong conclusions, recommendations, therapeutic directions cannot be made"
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Moreno JC, Uson Junior PLS. Clear cell sarcoma of the pancreas, an unusual cancer with unusual metastatic site or unusual primary site? World J Clin Cases 2024; 12(25): 5653-5656 [DOI: 10.12998/wjcc.v12.i25.5653]
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12
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"A concise, comprehensive, complex and well structured study. There are no grammatical/spelling errors throughout the manuscript and the topic debated is of a great interest due to the fact that we need a therapeutic strategy for HP eradication with good efficacy and less adverse events."
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Huang XP, Liu YJ, Lin SW, Shao YF, Qiu F, Qiu QW, Xu ZK, Chen JX, Chen LH, Lin ZQ, Dai WH, Zhang MQ, Jiang Q, Xiao ZQ, Cheng XX, Zhang XF, You WB, Chen W, Li LQ, Lin WX, Wang YF, Lai FJ, Chen LQ, Huang ZH, Zheng WQ, Wei JQ, Lin ZH. Vonoprazan-amoxicillin dual therapy for Helicobacter pylori eradication in Chinese population: A prospective, multicenter, randomized, two-stage study. World J Gastroenterol 2024; 30(27): 3304-3313 [DOI: 10.3748/wjg.v30.i27.3304]
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13
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"This is an interesting overview on a very recent and important subject. Introduction is well developed, Results are supported by a robust literature, the figure is clear. The session of Material and Methods is not present, in my opinion is better to know the selection of articles and sources. Type C"
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Barkhordarian M, Tran HHV, Menon A, Pulipaka SP, Aguilar IK, Fuertes A, Dey S, Chacko AA, Sethi T, Bangolo A, Weissman S. Innovation in pathogenesis and management of aortic aneurysm. World J Exp Med 2024; 14(2): 91408 [PMID: 38948412 DOI: 10.5493/wjem.v14.i2.91408]
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14
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"Dear Editor,
Thanks for your inviting, I would like to assess this article.
1. It is a systematic review, and it meets the ethical requirments.
2. The methods were effective.
3.The results were authentic and universal significance validated.
4. The tables and flowchart were well constructed.
5. The biostatistics data was simple in this article, and no obvious mistake was found.
6. The cited references were relatively new, especially most of the studies were included in the article were published within last four years.
7. The language in this article is good and clearly express the information.
8. The study concluded that the implementation of 3D printing and PSI for primary THA can significantly improve the positioning accuracy of the acetabular cup component and reduce the number of complications caused by malposition. This is consistent with our practice in recent years, especially for revision surgeries. I suggest the authors try to further study on redesigning the implants individually based on 3D printing techniques."
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Crone TP, Cornelissen BMW, Van Oldenrijk J, Bos PK, Veltman ES. Intraoperative application of three-dimensional printed guides in total hip arthroplasty: A systematic review. World J Orthop 2024; 15(7): 660-667 [DOI: 10.5312/wjo.v15.i7.660]
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15
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"Colon polyps include tubular adenoma and sessile serrated polyp. Please explain the intestinal flora that causes these polyps. After polypectomy, I think it is necessary to correct the intestinal flora in order to prevent polyps from developing again. What measures should be taken?"
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Intarajak T, Udomchaiprasertkul W, Khoiri AN, Sutheeworapong S, Kusonmano K, Kittichotirat W, Thammarongtham C, Cheevadhanarak S. Distinct gut microbiomes in Thai patients with colorectal polyps. World J Gastroenterol 2024; 30(27): 3336-3355 [DOI: 10.3748/wjg.v30.i27.3336]
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16
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"Ethics: The ethical approval form is provided by the authors and meets the requirements.
Methods: The experimental method is effective. It be repeated by fellow researchers (according to adequate textual/citation content presented).
Results: The results look true and authentic. The theory or hypothesis is of universal significance. Due to a case report, it is not validated. Only multicentric studies on the subject can validate the theory.
Figures and tables: The authors provide perfect tables, line charts and/or graphs.
Biostatistics: This is a case report without biostatistics.
References: Does the author scientifically and reasonably cite the latest references which are important in this field and related to the scientific problems and research hypotheses addressed in the study?
Language: The language in the article correctly, clearly, and concisely express the information.
Caveats or drawbacks: Nothing new or novel here."
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Zhang Y, Cui YF. Severe acute pancreatitis complicated with intra-abdominal infection secondary to trauma: A case report. World J Clin Cases 2024; 12(25): 5821-5831 [DOI: 10.12998/wjcc.v12.i25.5821]
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17
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"B. This is a well structured mini-review on the subject, with good figures and a clear table of the results. There are a lot of references to support the Results of the article.
Conclusion and future direction session very good.
Materials and Methods session is not present because it is a narrative review, but in my opinion, I prefer to read the way in which authors have taken the informations. "
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Oey O, Wijaya W, Redfern A. Eribulin in breast cancer: Current insights and therapeutic perspectives. World J Exp Med 2024; 14(2): 92558 [PMID: 38948420 DOI: 10.5493/wjem.v14.i2.92558]
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18
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"Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied."
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Guo CY, Wei YX. Splenic subcapsular hematoma following endoscopic retrograde cholangiopancreatography: A case report and review of literature. World J Clin Cases 2024; 12(24): 5613-5621 [DOI: 10.12998/wjcc.v12.i24.5613]
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19
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"Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied."
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Kar H, Khabbazazar D, Acar N, Karasu Ş, Bağ H, Cengiz F, Dilek ON. Are all primary omental infarcts truly idiopathic? Five case reports. World J Clin Cases 2024; 12(24): 5596-5603 [DOI: 10.12998/wjcc.v12.i24.5596]
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20
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"Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied."
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Mei LF, Gan Q, Hu J, Li YX, Tian R, Shi CJ. Assessment of early factors for identification or prediction severe acute pancreatitis in pregnancy. World J Clin Cases 2024; 12(24): 5502-5512 [DOI: 10.12998/wjcc.v12.i24.5502]
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21
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"Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied."
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Maity R, Dhali A, Biswas J. Importance of risk assessment, endoscopic hemostasis, and recent advancements in the management of acute non-variceal upper gastrointestinal bleeding. World J Clin Cases 2024; 12(24): 5462-5467 [DOI: 10.12998/wjcc.v12.i24.5462]
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22
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"With interest I read the following article:
1 Ethics: N/A given manuscript type
2 Methods: N/A given manuscript type
3 Results: N/A given manuscript type
4 Figures and tables: The included table enhances the readability of the article
5 Biostatistics: N/A given manuscript type
6 References: The references are appropriate/up-to-date
7 Language: The is a concise/well-written review
8 Caveats or drawbacks: N/A"
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Subramanian A, Jahabardeen A, Thamaraikani T, Vellapandian C. More on the interplay between gut microbiota, autophagy, and inflammatory bowel disease is needed. World J Gastroenterol 2024; 30(27): 3356-3360 [DOI: 10.3748/wjg.v30.i27.3356]
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23
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"This is a very good study highlighting the importance of correction of ischemia in the healing of diabetes foot ulcer. In addition, application of vacuum assisted closure further enhanced the healing rate. However, the small sample size, presence of many confounders and retrospective study design were few limitations of this study."
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Lei FR, Shen XF, Zhang C, Li XQ, Zhuang H, Sang HF. Clinical efficacy of endovascular revascularization combined with vacuum-assisted closure for the treatment of diabetic foot. World J Diabetes 2024; 15(7): 1499-1508 [DOI: 10.4239/wjd.v15.i7.1499]
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24
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"With interest I read this editorial on the performance and adverse event profile of MSE. Please see my comments below:
1 Ethics: Not applicable given manuscript type
2 Methods: Not applicable given manuscript type
3 Results: Not applicable given manuscript type
4 Figures and tables: The provided figures/tables enhance the readability of the manuscript
5 Biostatistics: Not applicable given manuscript type
6 References: The references are appropriate/up-to-date
7 Language: This is a concise/well written review of an important and timely topic in the literature.
8 Caveats or drawbacks: None"
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Mussetto A, Merola E, Casadei C, Salvi D, Fornaroli F, Cocca S, Trebbi M, Gabbrielli A, Spada C, Michielan A. Device-assisted enteroscopy: Are we ready to dismiss the spiral? World J Gastroenterol 2024; 30(26): 3185-3192 [DOI: 10.3748/wjg.v30.i26.3185]
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25
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"Interesting and timely article as the scientific world is heading towards potential cure for type 1 diabetes. "
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Ma XL, Ge D, Hu XJ. Evaluation of teplizumab's efficacy and safety in treatment of type 1 diabetes mellitus: A systematic review and meta-analysis. World J Diabetes 2024; 15(7): 1615-1626 [DOI: 10.4239/wjd.v15.i7.1615]
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26
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"This is very interesting paper.T Zhang et al in 2021 write A hepatocellular carcinoma (HCC) prediction score constructed from age, platelet count, and liver stiffness measurement at two-dimensional shear-wave elastography, or APS score, higher than 60 is predictive of higher risk of HCC development in patients with chronic hepatitis B. Please comment about T Zhang's paper."
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Jiang D, Qian Y, Gu YJ, Wang R, Yu H, Dong H, Chen DY, Chen Y, Jiang HZ, Tan BB, Peng M, Li YR. Predicting hepatocellular carcinoma: A new non-invasive model based on shear wave elastography. World J Gastroenterol 2024; 30(25): 3166-3178 [PMID: 39006386 DOI: 10.3748/wjg.v30.i25.3166]
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27
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"The introduction of artificial intelligence (AI) technologies into medicine is a significant trend in the field of healthcare. AI and neuronets are capable of radically changing the world of medicine: transforming the diagnostic system, promoting the development of new drugs, improving the quality of general medical services, and reducing costs. In future, the possibilities of AI will become almost limitless. Understanding the importance of discussing the main caveats, the presented article is an actual topic. This review discusses the current active use of AI technologies in gastroenterology. The authors primarily emphasized areas that are currently the most promising in practical healthcare. These technologies are based on machine learning techniques. Using limited examples of liver diseases, esophageal lesions, peptic ulcer disease, and computer-aided endoscopy, the authors described the pros and cons of AI in gastroenterology. Considering that AI in gastroenterology is primarily used in endoscopic image analysis, radiology, and histopathology, this approach is justified."
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Sridhar GR, Siva Prasad AV, Lakshmi G. Scope and caveats: Artificial intelligence in gastroenterology. Artif Intell Gastroenterol 2024; 5(1): 91607 [DOI: 10.35712/aig.v5.i1.91607]
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28
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"Artificial intelligence (AI) is increasingly used in the world today, and the field of medicine is no exception. The ability of AI to radically transform diagnostic processes, accelerate the creation of new drugs, and improve the quality of medical care opens up enormous opportunities for optimizing the healthcare sector. Currently, neural networks are actively used to process medical images and help doctors make diagnoses and choose treatment strategies. AI helps in the interpretation of X-rays, MRI, and other images, which allows for accurate and quick diagnosis of various diseases, such as cancer of various localizations or fractures. Machine learning technologies are able to detect details that may be invisible to the human eye. AI is increasingly being used to prevent and treat diseases, providing medical professionals and patients with new tools for decision-making. The opportunities that open up look extremely promising. Other artificial intelligence-based solutions in medicine cover a wide range of applications, from data analysis to training and drug development.
The study presented by the authors uses the ChatGPT language model to evaluate the accuracy of GPT-4 in providing accurate and reproducible answers to SIBO-related patient questions. Overall, the authors present a study that allows them to both examine the value of large language models such as GPT-4 in SIBO-related patient learning and highlight the limitations of GPT-4 in its current form due to the significant number of its responses containing inaccurate or outdated information and the low reproducibility of its answer accuracy. The value of this study lies not only in the analysis of the raw material but also in assessing the potential of AI language models in minimizing potential harm when using AI technologies for diseases with complex and less standardized diagnosis and treatment."
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Schlussel L, Samaan JS, Chan Y, Chang B, Yeo YH, Ng WH, Rezaie A. Evaluating the accuracy and reproducibility of ChatGPT-4 in answering patient questions related to small intestinal bacterial overgrowth. Artif Intell Gastroenterol 2024; 5(1): 90503 [DOI: 10.35712/aig.v5.i1.90503]
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29
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"1. The study type is not clear (descriptive review / systematic review)
2. Unplanned readmission, 30 day mortality are some of the markers which can help in devising the criteria for direct discharge to home
3. limitations such as timeline, logistics, advanced specialist care can change the outcome
"
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Hassan EM, Jama AB, Sharaf A, Shaikh A, El Labban M, Surani S, Khan SA. Discharging patients home from the intensive care unit: A new trend. World J Clin Cases 2024; 12(23): 5313-5319 [DOI: 10.12998/wjcc.v12.i23.5313]
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30
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"1. The distinction between psychological and neurological illness is not clear
2. The impact can be variable depending on the group studied like children, pregnant women, college students etc
3. Use of specialist (behavioural therapy) as well as generalist care (counselling, guidance, motivation) can be part of interventions"
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Hu HS, Sun BQ. Understanding the etiology of mental health problems in post-rehabilitation COVID-19 patients: Insights and strategies for effective intervention. World J Clin Cases 2024; 12(23): 5308-5312 [DOI: 10.12998/wjcc.v12.i23.5308]
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31
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"1. Inclusion of the tests as an algorithm / table would help in better understanding
2. Gene Xpert of biopsy tissue rather than fecal specimen is advised
3. Use of immunological markers especially (FOXP3 + Treg cell enumeration) in differentiating Crohns' vs GI TB"
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Brown L, Colwill M, Poullis A. Gastrointestinal tuberculosis: Diagnostic approaches for this uncommon pathology. World J Clin Cases 2024; 12(23): 5283-5287 [DOI: 10.12998/wjcc.v12.i23.5283]
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32
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"Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied."
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Wang YK, Liu YH, Shuang WB. Giant retroperitoneal hemolymphangioma: A case report and review of literature. World J Clin Cases 2024; 12(22): 5258-5262 [DOI: 10.12998/wjcc.v12.i22.5258]
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33
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"Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied."
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Sun YH, Lu SS, Fang Y, Xiong Z, Sun QY, Huang J. Rare primary colonic T cell lymphoma with curative resection by endoscopic submucosal dissection: A case report. World J Clin Cases 2024; 12(22): 5229-5235 [DOI: 10.12998/wjcc.v12.i22.5229]
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34
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"Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied."
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Toshima T, Inada R, Sakamoto S, Takeda E, Yoshioka T, Kumon K, Mimura N, Takata N, Tabuchi M, Oishi K, Sato T, Sui K, Okabayashi T, Ozaki K, Nakamura T, Shibuya Y, Matsumoto M, Iwata J. Goblet cell carcinoid of the appendix: Six case reports. World J Clin Cases 2024; 12(22): 5217-5224 [DOI: 10.12998/wjcc.v12.i22.5217]
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35
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"Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied."
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Wang T, Jiang J, Guo LL, Chen X, Chen EB. Heterotopic pancreas in the gallbladder: A case report. World J Clin Cases 2024; 12(22): 5140-5144 [DOI: 10.12998/wjcc.v12.i22.5140]
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36
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"Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied."
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Li YQ, Liu Y, Peng ZQ, Fang R, Xu HY. Enhanced recovery after surgery-based nursing in older patients with postoperative intestinal obstruction after gastric cancer surgery: A retrospective study. World J Clin Cases 2024; 12(22): 4983-4991 [DOI: 10.12998/wjcc.v12.i22.4983]
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37
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"Very interesting and rigurous. "
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Balakumar P. Unleashing the pathological role of epithelial-to-mesenchymal transition in diabetic nephropathy: The intricate connection with multifaceted mechanism. World J Nephrol 2024; 13(2): 95410 [PMID: 38983761 DOI: 10.5527/wjn.v13.i2.95410]
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38
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"Nothing really new"
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Lathiya MK, Errabelli P, Roy S, Mareedu N. Severe acute kidney injury due to oxalate crystal induced severe interstitial nephritis: A case report. World J Nephrol 2024; 13(2): 93976 [PMID: 38983760 DOI: 10.5527/wjn.v13.i2.93976]
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39
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"No clear explanation how the scientifical search was done is given and no novelty is found in this review."
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Pérez-Aizpurua X, Cabello Benavente R, Bueno Serrano G, Alcázar Peral JM, Gómez-Jordana Mañas B, Tufet i Jaumot J, Ruiz de Castroviejo Blanco J, Osorio Ospina F, Gonzalez-Enguita C. Obstructive uropathy: Overview of the pathogenesis, etiology and management of a prevalent cause of acute kidney injury. World J Nephrol 2024; 13(2): 93322 [PMID: 38983763 DOI: 10.5527/wjn.v13.i2.93322]
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40
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"The approach is too simple and no important conclusions are reached."
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de Souza SP, Caldas JR, Lopes MB, Duarte Silveira MA, Coelho FO, Oliveira Queiroz I, Domingues Cury P, Passos RDH. Physico-chemical characterization of acid base disorders in patients with COVID-19: A cohort study. World J Nephrol 2024; 13(2): 92498 [PMID: 38983762 DOI: 10.5527/wjn.v13.i2.92498]
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41
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"This article provides a comprehensive overview of the status and outlook of the clinical healing of CHB. It not only discusses the strategy and challenges of the previous treatment, but also covers the potential for treatment of special people and the research of new drugs. The article emphasizes the importance of personalized therapy and points out the direction of future research, including the potential applications of immunotherapy and gene editing techniques. In addition, the author's in-depth analysis of the treatment strategy provides a valuable insight into the treatment of CHB patients. Overall, this article is a valuable resource for researchers and medical professionals in hepatitis B."
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Li YP, Liu CR, He L, Dang SS. Hepatitis B cure: Current situation and prospects. World J Hepatol 2024; 16(6): 900-911 [PMID: 38948438 DOI: 10.4254/wjh.v16.i6.900]
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42
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"This study has a promising topic, which want to determine whether layer-specific global longitudinal strain (GLS) combined with peak strain dispersion (PSD) can be used to assess left ventricle (LV) myocardium systolic dysfunction in T2DM patients or without hypertension (HP). The results showed layer-specific GLS and PSD can find LV myocardium systolic dysfunction in T2DM patients with HP. T2DM patients with HP have more severe LV myocardium systolic dysfunction than T2DM patients without HP and healthy subjects. The article has delivered important clinical message and should be of great interest to the readers. The submission is worthy of publication."
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Chen ZG, Li GA, Huang J, Fan L. Subclinical impairment of left ventricular myocardium function in type 2 diabetes mellitus patients with or without hypertension. World J Diabetes 2024; 15(6): 1272-1279 [PMID: 38983828 DOI: 10.4239/wjd.v15.i6.1272]
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43
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"Indeed, a potential target for therapy of liver diseases may be the gut microbiota, which is the main regulator of bacterial translocation and systemic inflammation. There is nothing new in this article."
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Kotlyarov S. Importance of the gut microbiota in the gut-liver axis in normal and liver disease. World J Hepatol 2024; 16(6): 878-882 [PMID: 38948437 DOI: 10.4254/wjh.v16.i6.878]
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44
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"In this review article, the authors briefly introduce the molecular process of mitophagy and summarize its roles in gastric cancer, colorectal cancer, and inflammatory bowel diseases. Similar to its physiological effects, mitophagy has been reported to show a dual role in each disease. A reduction in the number of damaged mitochondria maintains mitochondrial quality and decreases the risk of developing a pathophysiological state. On the other hand, the reduced number of mitochondria hinders physiological cellular processes and promotes cancer development, resistance to anti-cancer drugs, and inflammation. Because it is difficult to understand these controversial effects of mitophagy, it would be helpful to illustrate the different environments leading to the opposite effects of mitophagy."
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Gao DL, Lin MR, Ge N, Guo JT, Yang F, Sun SY. From macroautophagy to mitophagy: Unveiling the hidden role of mitophagy in gastrointestinal disorders. World J Gastroenterol 2024; 30(23): 2934-2946 [PMID: 38946875 DOI: 10.3748/wjg.v30.i23.2934]
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45
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"Objectivity
The study titled "Association between gut microbiota and hepatocellular carcinoma and biliary tract cancer: A mendelian randomization study" demonstrates high objectivity by utilizing well-established Mendelian randomization (MR) methods to investigate the relationship between gut microbiota and hepatocellular carcinoma (HCC) and biliary tract cancer (BTC). This method helps mitigate confounding factors and allows for a more accurate determination of causality.
Resolved Issues:
• The study employs a large dataset from the MiBioGen consortium and the IEU open GWAS platform, ensuring a comprehensive analysis.
• Multiple biases and heterogeneity tests are conducted to ensure result reliability.
Unresolved Issues:
• The selection threshold for SNPs was adjusted from 5×10−85 \times 10^{-8}5×10−8 to 1×10−51 \times 10^{-5}1×10−5 due to limited SNP availability, which might affect result precision.
Credibility
The credibility of the article is supported by several factors:
1. Peer-Reviewed Journal: The article is published in the "World Journal of Clinical Cases," a peer-reviewed journal.
2. Expert Authors: The authors, Ye Zhang, Fa-Ji Yang, Qi-Rong Jiang, and others, are affiliated with reputable institutions such as the Shandong Provincial Hospital.
3. Methodology: The study uses Mendelian randomization, a robust epidemiological method, to infer causality.
4. Data Sources: Data is obtained from recognized sources, including MiBioGen and the IEU open GWAS platform.
Resolved Issues:
• The use of multiple MR methods (Inverse-Variance Weighted, weighted median method, MR-Egger regression) and sensitivity analyses increases the study’s robustness.
Unresolved Issues:
• The potential bias due to regional and ethnic differences in the GWAS data used.
Scientific Quality
The scientific quality of the article is evidenced by:
1. Novelty: The study addresses a significant gap in the literature regarding the relationship between gut microbiota and HCC and BTC.
2. Methodological Rigor: Extensive statistical analyses and multiple testing methods ensure the reliability of the results.
3. Significance: The findings could have important implications for the early screening and treatment of HCC and BTC.
Resolved Issues:
• The study identifies specific gut microbiota associated with increased or decreased risks for HCC and BTC, providing new insights into disease mechanisms.
• Tests for heterogeneity and pleiotropy confirm the robustness of the causal associations identified.
Unresolved Issues:
• The broader implications of the findings require further experimental validation to confirm the mechanisms through which gut microbiota influence HCC and BTC.
Conclusion
Conclusion: The study successfully identifies causative relationships between specific gut microbiota and HCC and BTC using Mendelian randomization analysis. These findings provide a foundation for future research into gut microbiota's role in these cancers, potentially informing therapeutic strategies."
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Zhang Y, Yang FJ, Jiang QR, Gao HJ, Song X, Zhu HQ, Zhou X, Lu J. Association between gut microbiota and hepatocellular carcinoma and biliary tract cancer: A mendelian randomization study. World J Clin Cases 2024; 12(18): 3497-3504 [PMID: 38983434 DOI: 10.12998/wjcc.v12.i18.3497]
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46
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"Objectivity
• Strengths:
o The study clearly outlines its objective to investigate the effects of acetylcysteine on microinflammation and lung ventilation in patients with phlegm-heat and blood-stasis-type AECOPD.
o The use of a randomized controlled trial design adds rigor and objectivity to the study.
o The methodology is detailed, describing the inclusion and exclusion criteria, randomization process, and intervention specifics.
• Weaknesses:
o Potential bias may arise from the single-center design, which may limit the generalizability of the findings.
o The study's authors are from the same institution, which may introduce institutional bias.
Resolved Issues:
• The authors have addressed potential biases by ensuring randomization and blinding.
Unresolved Issues:
• No detailed mention of any external validation or multicenter approach to enhance objectivity.
Credibility
• Strengths:
o The study is published in a peer-reviewed journal, enhancing its credibility.
o The authors have significant affiliations with reputable institutions, which adds to the study’s credibility.
o Detailed statistical analysis and adherence to CONSORT guidelines further support the study's credibility.
• Weaknesses:
o The sample size, while adequate, is relatively small, which might affect the robustness of the results.
o Long-term effects and safety were not assessed due to the 14-day intervention period.
Resolved Issues:
• The study protocol was approved by an ethics committee, and informed consent was obtained, addressing ethical concerns.
Unresolved Issues:
• The short duration of the study does not allow for assessment of long-term efficacy and safety.
Scientific Quality
• Strengths:
o The study employs a robust methodology with well-defined outcome measures.
o Significant improvements in inflammatory markers and lung function parameters are reported, with statistical analysis supporting these findings.
o The discussion is thorough, linking findings to existing literature and explaining potential mechanisms.
• Weaknesses:
o The study does not explore the mechanism of action of acetylcysteine in depth.
o Some aspects of patient-reported outcomes, such as quality of life and exacerbation frequency, are not included.
Resolved Issues:
• The statistical methods used are appropriate and detailed, providing clarity on the results.
• The study addresses potential limitations and suggests areas for future research.
Unresolved Issues:
• A more in-depth exploration of the biological mechanisms underlying the observed effects could enhance the scientific quality.
• The study could benefit from a more extensive assessment of patient-centered outcomes.
Conclusion
The article provides valuable insights into the potential benefits of acetylcysteine as an adjunctive therapy for AECOPD, particularly for patients with phlegm-heat and blood-stasis type. While the study is methodologically sound and presents compelling evidence, future research should address the unresolved issues and expand on the findings to further enhance the understanding and application of acetylcysteine in clinical practice.
"
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Huang LY, Huang B, Lv Z, Lu XD. Effects of acetylcysteine on micro-inflammation and pulmonary ventilation in chronic obstructive pulmonary disease exacerbation. World J Clin Cases 2024; 12(18): 3482-3490 [PMID: 38983436 DOI: 10.12998/wjcc.v12.i18.3482]
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47
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"Objectivity
Strengths:
1. Randomized Controlled Trial Design: The study utilizes a randomized controlled trial (RCT) design, which is the gold standard for clinical trials, enhancing the objectivity of the findings.
2. Clear Aim and Methods: The aim of the study is clearly stated, and the methods are well-defined, ensuring that the research question is addressed systematically.
3. Detailed Inclusion and Exclusion Criteria: The study includes detailed inclusion and exclusion criteria, ensuring a well-defined study population and reducing selection bias.
Weaknesses:
1. Single-Blind Design: The single-blind design (only participants are blinded) may introduce some bias as the investigators are aware of the group allocations.
2. Limited Generalizability: The study is conducted in a single center, which may limit the generalizability of the findings to other populations or settings.
Credibility
Strengths:
1. External Peer Review: The article was externally peer-reviewed, which adds to the credibility of the study.
2. Institutional Review Board Approval: The study was reviewed and approved by an institutional review board, ensuring that ethical standards were maintained.
3. Conflict of Interest Statement: The authors have declared no conflicts of interest, which enhances the trustworthiness of the findings.
Weaknesses:
1. Author Affiliations: All authors are from the same institution, which may introduce institutional bias.
2. Funding Source: The study mentions government subsidies but lacks detailed information on how the funding source might have influenced the research.
Scientific Quality
Strengths:
1. Comprehensive Data Analysis: The study employs appropriate statistical methods to analyze the data, including t-tests and chi-square tests.
2. Detailed Outcome Measures: The study uses well-established measures such as serum levels of motilin, 5-hydroxytryptamine, VIP, and Wexner scores for anal incontinence.
3. Significant Findings: The study reports statistically significant differences between the treatment and control groups, supporting the efficacy of acupuncture therapy.
Weaknesses:
1. Grade C for Scientific Quality: According to the peer-review report, the scientific quality of the study is graded C, indicating that there might be concerns about the robustness of the study design or methodology.
2. Lack of Long-Term Follow-Up: The study does not provide long-term follow-up data, which is crucial to understanding the sustained effects of acupuncture therapy.
Resolved and Unresolved Issues
Resolved Issues:
1. Peer Review and Ethical Approval: The study has been peer-reviewed and ethically approved, addressing initial concerns about study oversight.
2. Statistical Analysis: The use of appropriate statistical methods to analyze the data has been adequately addressed.
Unresolved Issues:
1. Blinding Method: The single-blind design remains an unresolved issue, which could impact the study's internal validity.
2. Generalizability: The study’s findings are limited to a specific population and setting, which remains an unresolved issue regarding the applicability of results to broader populations.
Conclusion
The article provides valuable insights into the efficacy of acupuncture therapy for anal function rehabilitation post low-tension rectal cancer surgery. Despite some limitations, the study's strengths in design, data analysis, and ethical conduct support its scientific contribution. Addressing the unresolved issues in future research will further enhance the quality and impact of studies in this field, thereby fostering reader interest and promoting the development of the discipline."
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Shen LZ, Li W, Liu ZL, Wang N, Liu YF, Miao LL. Evaluating the clinical application and effect of acupuncture therapy in anal function rehabilitation after low-tension rectal cancer surgery. World J Clin Cases 2024; 12(18): 3476-3481 [PMID: 38983413 DOI: 10.12998/wjcc.v12.i18.3476]
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48
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"Objectivity
The article maintains a high degree of objectivity, adhering to the principles of a randomized, double-blind, placebo-controlled trial. This design minimizes bias and enhances the reliability of the results. The authors clearly state their hypothesis, methodology, and statistical analysis, providing transparency in their research process.
Resolved Issues:
Blinding and Randomization: The study employed a rigorous randomization and blinding process, ensuring that neither participants nor researchers knew the treatment allocations. This has been successfully implemented, as confirmed by the balanced baseline characteristics between the two groups.
Clear Hypothesis and Aim: The authors clearly articulated the aim of the study to investigate the effects of dapagliflozin on uric acid levels in patients with CHF and hyperuricemia.
Unresolved Issues:
Potential Biases: While the study design is robust, the article could further discuss potential biases that might arise from the single-blind peer-review model used for evaluating the manuscript.
Credibility
The article demonstrates high credibility, supported by the following factors:
Peer Review: The article was externally peer-reviewed, enhancing its credibility.
Affiliations and Contributions: The authors are affiliated with reputable institutions, and their roles in the study are well-defined.
Funding and Conflict of Interest: The study acknowledges funding from a General Medical Research Fund Project and declares no conflicts of interest, which supports the credibility of the findings.
Resolved Issues:
Peer Review Process: The study has undergone external peer review, and the authors have revised the manuscript based on reviewers' feedback.
Institutional Approval: The study received ethical approval from the Ethics Committee of Harbin 242 Hospital.
Unresolved Issues:
Generalizability: The study population was limited to patients in China, which may affect the generalizability of the findings to other populations. The authors should address this limitation in future research.
Scientific Quality
The scientific quality of the article is satisfactory, with well-defined methodologies and robust statistical analyses. The study successfully demonstrates the efficacy of dapagliflozin in lowering serum uric acid levels and improving clinical outcomes in CHF patients with hyperuricemia.
Resolved Issues:
Study Design: The randomized, double-blind, placebo-controlled design enhances the scientific rigor of the study.
Statistical Analysis: The use of appropriate statistical methods, including analysis of covariance and Cox proportional hazards regression, ensures the reliability of the results.
Unresolved Issues:
Mechanisms and Mediators: The study did not explore the mechanisms and mediators of dapagliflozin's action on uric acid and cardiovascular outcomes. Future research should investigate these aspects.
Secondary Biomarkers: The article lacks data on other biomarkers associated with CHF and hyperuricemia, such as oxidative stress and inflammation markers.
Future Research and Recommendations
To further enhance the scientific quality and impact of future research, the following recommendations are made:
Expand Study Populations: Conduct similar studies in diverse populations to improve the generalizability of the findings.
Investigate Mechanisms: Explore the underlying mechanisms and mediators of dapagliflozin’s effects on uric acid and cardiovascular outcomes.
Include Additional Biomarkers: Measure and analyze additional biomarkers related to CHF and hyperuricemia to provide a more comprehensive understanding of the disease and treatment effects.
Cost-Effectiveness Analysis: Conduct cost-effectiveness analyses of dapagliflozin versus placebo in CHF patients with hyperuricemia to inform clinical and policy decision-making.
Conclusion
The article "Effect of Dapagliflozin on Uric Acid in Patients with Chronic Heart Failure and Hyperuricemia" presents objective, credible, and scientifically sound research. While the study effectively addresses its primary and secondary endpoints, future research should focus on expanding the study populations, investigating additional biomarkers, and exploring the mechanisms of action to further validate and build upon these findings."
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Lin MJ, Zou SB, Zhu BX. Effect of dapagliflozin on uric acid in patients with chronic heart failure and hyperuricemia. World J Clin Cases 2024; 12(18): 3468-3475 [PMID: 38983399 DOI: 10.12998/wjcc.v12.i18.3468]
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49
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"Objectivity
The article aims to evaluate the diagnostic value of serum cystatin C (Cys-C), monocyte/high-density lipoprotein cholesterol ratio (MHR), and uric acid (UA) for coronary heart disease (CHD) and heart failure (HF). The study is well-structured, with clear objectives, methods, results, and conclusions, adhering to the scientific method.
Resolved Issues:
• Clear definition of study population and criteria for inclusion/exclusion.
• Detailed methodology for biochemical analysis and diagnostic criteria.
• Ethical approval and informed consent obtained.
Unresolved Issues:
• The study's retrospective design introduces potential biases that are acknowledged but not fully addressed.
• The sample size is relatively small, limiting the generalizability of the findings.
Credibility
The authors provide a solid background and rationale for selecting the biomarkers, supported by relevant references. The study is peer-reviewed, which adds to its credibility. However, some areas could be improved.
Resolved Issues:
• Comprehensive literature review supporting the choice of biomarkers.
• Methodology and statistical analysis are adequately described.
• Conflicts of interest are declared as non-existent.
Unresolved Issues:
• The study's findings are based on a single-center, which might limit external validity.
• The potential influence of confounding factors, such as other comorbidities, is not fully explored.
Scientific Quality
The scientific quality of the study is moderate, with a rigorous approach to data collection and analysis. The results are presented with appropriate statistical measures, and the discussion reflects on the limitations and potential implications of the findings.
Resolved Issues:
• Use of standard operating procedures and quality control measures in biochemical analysis.
• Robust statistical analysis with ROC curve evaluation and clear presentation of diagnostic performance.
Unresolved Issues:
• The study does not include a validation cohort to confirm the findings.
• The dynamic changes in biomarker levels over time are not assessed, which could provide additional insights.
Future Steps and Recommendations
To enhance the study's impact and contribute to future research, the authors should consider the following steps:
1. Increase Sample Size: Conduct multicenter studies with larger and more diverse populations to validate the findings.
2. Prospective Design: Implement prospective, randomized studies to establish causal relationships and mitigate retrospective bias.
3. Longitudinal Analysis: Measure biomarker levels at multiple time points to assess their dynamic changes and predictive value.
4. External Validation: Compare results with external data sources or published studies to strengthen the evidence.
5. Explore Confounding Factors: Conduct subgroup analyses to understand the influence of various comorbidities and other confounding factors on biomarker levels.
Conclusion
The study provides valuable insights into the potential use of Cys-C, MHR, and UA as biomarkers for diagnosing CHD and HF. While the findings are promising, further research with larger, more diverse populations and a prospective design is necessary to confirm and extend these results. Incorporating these biomarkers into diagnostic protocols could improve the accuracy and prognostic evaluation of patients with CHD and HF, ultimately enhancing clinical decision-making and patient outcomes."
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Li M, Yuan DH, Yang Z, Lu TX, Zou XB. Serum cystatin C, monocyte/high-density lipoprotein-C ratio, and uric acid for the diagnosis of coronary heart disease and heart failure. World J Clin Cases 2024; 12(18): 3461-3467 [PMID: 38983396 DOI: 10.12998/wjcc.v12.i18.3461]
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50
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"Objectivity:
The article adopts a descriptive phenomenological approach to investigate the factors influencing community nurses' abilities to manage critical and emergency conditions. The objectivity is maintained through:
Data Collection: Utilizing semi-structured interviews with 17 community nurses from seven communities, ensuring diverse perspectives.
Data Analysis: Employing Colaizzi's seven-step analysis method, a systematic approach for phenomenological data analysis, which enhances the reliability and validity of the findings.
Credibility:
The study's credibility is supported by:
Peer Review: The article was externally peer-reviewed under a single-blind model, adding a layer of scrutiny to the research process.
Ethical Considerations: The study was approved by the Beihua University Medical Ethics Committee, and informed consent was obtained from all participants.
Author Contributions and Support: Clear delineation of contributions from various authors and support from the Shanghai Changning District Health Commission adds to the study's trustworthiness.
Scientific Quality:
The scientific quality of the article is assessed based on:
Research Design: A qualitative approach is suitable for exploring complex, multifaceted issues such as the facilitators and barriers to community nurses' emergency care abilities.
Data Collection and Analysis: The rigorous process of data collection and analysis, including transcription and thematic analysis, ensures comprehensive and accurate results.
Findings and Implications: The study identifies critical barriers (resource allocation, professional factors, personal literacy) and facilitators (professionalism, management attention, training) affecting community nurses' abilities, providing valuable insights for future interventions.
Resolved Issues:
Ethical Approval and Consent: The study successfully obtained ethical approval and informed consent, addressing initial ethical concerns.
Data Analysis: The use of Colaizzi's method ensures a structured and thorough analysis of interview data, resolving potential issues related to data interpretation.
Unresolved Issues:
Sample Size and Representation: Although 17 nurses from seven communities were interviewed, the sample size remains relatively small, which may limit the generalizability of the findings.
Longitudinal Follow-Up: The study does not include a longitudinal component to assess the long-term impact of identified barriers and facilitators on community nurses' abilities.
Future Research Directions:
To address the remaining issues and further enhance the study's impact:
Expand Sample Size: Future research should include a larger and more diverse sample of community nurses to improve the generalizability of the findings.
Incorporate Longitudinal Studies: Conduct longitudinal studies to assess the long-term effectiveness of interventions aimed at enhancing community nurses' critical care capabilities.
Focus on Practical Interventions: Develop and test specific training programs and resource allocation strategies to address identified barriers, providing practical solutions to improve community emergency care.
Conclusion:
The study provides a comprehensive analysis of the factors influencing community nurses' abilities to manage critical and emergency conditions. By addressing unresolved issues and incorporating future research directions, the study can significantly contribute to enhancing community emergency care and promoting the development of nursing practices."
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Cheng WL, Li R, Song Y, Qian FH, Sha SY, Song SY. Facilitating and hindering factors of community nurses' emergency and critical care treatment abilities: A qualitative study. World J Clin Cases 2024; 12(18): 3453-3460 [PMID: 38983421 DOI: 10.12998/wjcc.v12.i18.3453]
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