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4/16/2025 8:25:40 AM | Browse: 64 | Download: 66
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Received |
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2024-10-11 01:22 |
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Peer-Review Started |
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2024-10-29 00:45 |
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To Make the First Decision |
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Return for Revision |
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2025-01-20 06:34 |
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Revised |
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2025-02-02 02:21 |
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Second Decision |
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2025-02-28 02:34 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-02-28 07:31 |
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Articles in Press |
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2025-02-28 07:31 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-03-07 13:20 |
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Publish the Manuscript Online |
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2025-04-16 05:36 |
| ISSN |
2220-315x (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Dentistry, Oral Surgery & Medicine |
| Manuscript Type |
Retrospective Study |
| Article Title |
Hypoxia-inducible factor-1α at the invasive tumor front in oral squamous cell carcinoma
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Felipe Martins Silveira, Lauren Frenzel Schuch, Vanesa Pereira-Prado, Nelly Molina-Frechero, Sandra Lopez-Verdin, Marcelo Gómez Palacio-Gastélum, Miguel Arocena, Sven Niklander, Estefania Sicco and Ronell Bologna-Molina |
| Funding Agency and Grant Number |
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| Corresponding Author |
Ronell Bologna-Molina, PhD, Professor, Molecular Pathology Area, Department of Diagnosis in Pathology and Oral Medicine, University of the Republic, NA, Montevideo 11600, Uruguay. ronellbologna@hotmail.com |
| Key Words |
Hypoxia-inducible factor-1α; Oral squamous cell carcinoma; Immunohistochemistry; Vimentin; E-cadherin |
| Core Tip |
This study aimed to characterize the expression of Hypoxia-Inducible Factor 1-alpha (HIF-1α) at the invasive tumor front (ITF) in comparison to tumor islands in oral squamous cell carcinoma (OSCC) and to explore its relationship with E-cadherin and Vimentin expression. Based on the results of this study, HIF-1α appears to play a distinct role in OSCC tumor progression, underscoring the importance of exploring hypoxia-driven changes in cellular phenotype at the ITF of OSCC. |
| Publish Date |
2025-04-16 05:36 |
| Citation |
<p>Silveira FM, Schuch LF, Pereira-Prado V, Molina-Frechero N, Lopez-Verdin S, Gómez Palacio-Gastélum M, Arocena M, Niklander S, Sicco E, Bologna-Molina R. Hypoxia-inducible factor-1α at the invasive tumor front in oral squamous cell carcinoma. <i>World J Exp Med</i> 2025; 15(2): 102175</p> |
| URL |
https://www.wjgnet.com/2220-315x/full/v15/i2/102175.htm |
| DOI |
https://dx.doi.org/10.5493/wjem.v15.i2.102175 |
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