Publication Name	World Journal of Gastroenterology
Manuscript ID	103901
Country	China

Received	2024-12-04 08:30
Peer-Review Started	2024-12-04 08:30
To Make the First Decision
Return for Revision	2025-02-18 02:36
Revised	2025-03-03 13:01
Second Decision	2025-03-25 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-03-25 05:10
Articles in Press	2025-03-25 05:10
Publication Fee Transferred	2025-03-04 07:44
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-04-07 02:32
Publish the Manuscript Online	2025-04-11 02:19

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Oncology
Manuscript Type	Review
Article Title	Interplay of genetic and clinical factors in cancer-associated thrombosis: Deciphering the prothrombotic landscape of colorectal cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Duo-Gang Xu and Jing Tan
Funding Agency and Grant Number
Corresponding Author	Jing Tan, PhD, Professor, Department of General Surgery, Yan'an Hospital Affiliated to Kunming Medical University, No. 245 Renmin East Road, Panlong District, Kunming 650051, Yunnan Province, China. jingtan0915@163.com
Key Words	Colorectal cancer cell; Cancer-associated thrombosis; Venous thromboembolism; Tissue factor; Platelet
Core Tip	This comprehensive review examines the complex interplay between genetic and clinical factors in colorectal cancer (CRC)-associated thrombosis. It highlights how tumor-specific mechanisms, such as tissue factor and cancer procoagulant, actively contribute to the coagulation cascade, alongside clinical risk factors like age, gender, and obesity. By integrating both tumor biology and patient-specific characteristics, this study provides crucial insights into the prothrombotic tendencies of CRC, offering valuable perspectives for personalized therapies and improving patient management in CRC-associated venous thromboembolism.
Publish Date	2025-04-11 02:19
Citation	<p>Xu DG, Tan J. Interplay of genetic and clinical factors in cancer-associated thrombosis: Deciphering the prothrombotic landscape of colorectal cancer. <i>World J Gastroenterol</i> 2025; 31(14): 103901</p>
URL	https://www.wjgnet.com/1007-9327/full/v31/i14/103901.htm
DOI	https://dx.doi.org/10.3748/wjg.v31.i14.103901

Full Article (PDF)	WJG-31-103901-with-cover.pdf
Manuscript File	103901_Auto_Edited_060423.docx
Answering Reviewers	103901-answering-reviewers.pdf
Audio Core Tip	103901-audio.mp3
Conflict-of-Interest Disclosure Form	103901-conflict-of-interest-statement.pdf
Copyright License Agreement	103901-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	103901-non-native-speakers.pdf
Supplementary Material	103901-supplementary-material.pdf
Peer-review Report	103901-peer-reviews.pdf
Scientific Misconduct Check	103901-scientific-misconduct-check.png
Scientific Editor Work List	103901-scientific-editor-work-list.pdf
CrossCheck Report	103901-crosscheck-report.pdf