| ISSN |
1949-8462 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cardiac & Cardiovascular Systems |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Comparative effectiveness of transcatheter vs surgical aortic valve replacement: A systematic review and meta-analysis
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Iman Moradi, Muhammad Saqlain Mustafa, Jannat Sardar Sheikh, Behrooz Shojai Rahnama, Matthew Fredericks, Anil Kumar Yennam, Mustafa Arain, Utsow Saha, Andrew Richard Ma, Adithya Nagendran, Moosa Bin Omer, Muhammad Armaghan, Diana Carolina Cortés Jaimes, Nagavenkata Lova Surya Vamsi Avinash Bojanki and Muhammad Ashir Shafique |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Muhammad Saqlain Mustafa, MD, Senior Researcher, Department of Medicine, Jinnah Sindh Medical University, Iqbal Shaheed Road, Karachi, Sindh, Pakistan, Karachi 75510, Sindh, Pakistan. msaqlain.mustafa@gmail.com |
| Key Words |
Aortic stenosis; Meta-analysis; Surgical aortic valve replacement; Transcatheter aortic valve replacement; Treatment decision-making |
| Core Tip |
This systematic review and meta-analysis provide a comprehensive comparison of transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement in managing severe symptomatic aortic stenosis. TAVR demonstrated significant benefits, including reduced risks of acute kidney injury, major bleeding, and new-onset atrial fibrillation, particularly favoring high-risk surgical candidates. However, higher rates of permanent pacemaker implantation, vascular complications, and paravalvular leaks were observed with TAVR. Mortality and stroke rates were similar between interventions, underscoring the importance of individualized patient selection and shared decision-making to balance risks and optimize clinical outcomes. |
| Publish Date |
2025-04-21 08:12 |
| Citation |
<p>Moradi I, Mustafa MS, Sardar Sheikh J, Shojai Rahnama B, Fredericks M, Kumar Yennam A, Arain M, Saha U, Richard Ma A, Nagendran A, Bin Omer M, Armaghan M, Jaimes DCC, Avinash Bojanki NLSV, Shafique MA. Comparative effectiveness of transcatheter vs surgical aortic valve replacement: A systematic review and meta-analysis. <i>World J Cardiol</i> 2025; 17(4): 104168</p> |
| URL |
https://www.wjgnet.com/1949-8462/full/v17/i4/104168.htm |
| DOI |
https://dx.doi.org/10.4330/wjc.v17.i4.104168 |
