Publication Name	World Journal of Clinical Oncology
Manuscript ID	104959
Country	United States

Received	2025-01-07 03:41
Peer-Review Started	2025-01-07 03:41
To Make the First Decision
Return for Revision	2025-02-19 07:32
Revised	2025-02-23 18:02
Second Decision	2025-03-13 02:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-03-13 09:25
Articles in Press	2025-03-13 09:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-04-01 01:28
Publish the Manuscript Online	2025-07-22 09:23

ISSN	2218-4333 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Editorial
Article Title	Expanding horizons in esophageal squamous cell carcinoma: The promise of induction chemoimmunotherapy with radiotherapy
Manuscript Source	Invited Manuscript
All Author List	Wenxue Ma and Natalia Baran
Funding Agency and Grant Number	Funding Agency Grant Number National Science Centre, Poland 2021/43/B/NZ5/03345
Corresponding Author	Wenxue Ma, MD, PhD, Professor, Department of Medicine, Sanford Stem Cell Institute, and Moores Cancer Center, University of California San Diego, 2880 Torrey Pines Scenic Drive, San Diego, CA 92093, United States. wma@health.ucsd.edu
Key Words	Esophageal squamous cell carcinoma; Chemoimmunotherapy, Radiotherapy; Immune checkpoint inhibitors; Locally advanced cancer; Treatment outcomes
Core Tip	This editorial highlights the study by Wei et al, which examines the impact of induction chemoimmunotherapy followed by radiotherapy or concurrent chemoradiotherapy in patients with locally advanced esophageal squamous cell carcinoma (ESCC). The study demonstrates improved survival outcomes and a manageable safety profile, identifying the effectiveness of induction therapy and maintenance immunotherapy as key prognostic factors. This innovative approach represents a promising advancement in the treatment of ESCC and underscores the need for future prospective trials and mechanistic studies incorporating biomarker investigations to refine therapeutic strategies and enhance patient outcomes.
Publish Date	2025-07-22 09:23
Citation	<p>Ma W, Baran N. Expanding horizons in esophageal squamous cell carcinoma: The promise of induction chemoimmunotherapy with radiotherapy. <i>World J Clin Oncol</i> 2025; 16(7): 104959</p>
URL	https://www.wjgnet.com/2218-4333/full/v16/i7/104959.htm
DOI	https://dx.doi.org/10.5306/wjco.v16.i7.104959

Full Article (PDF)	WJCO-16-104959-with-cover.pdf
Manuscript File	104959_Auto_Edited_115424.docx
Answering Reviewers	104959-answering-reviewers.pdf
Audio Core Tip	104959-audio.m4a
Conflict-of-Interest Disclosure Form	104959-conflict-of-interest-statement.pdf
Copyright License Agreement	104959-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	104959-foundation-statement.pdf
Peer-review Report	104959-peer-reviews.pdf
Scientific Misconduct Check	104959-scientific-misconduct-check.png
Scientific Editor Work List	104959-scientific-editor-work-list.pdf
CrossCheck Report	104959-crosscheck-report.pdf