Publication Name	World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID	105242
Country	China

Received	2025-01-16 03:21
Peer-Review Started	2025-01-16 03:21
To Make the First Decision
Return for Revision	2025-02-22 02:14
Revised	2025-02-28 13:48
Second Decision	2025-03-20 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
Articles in Press	2025-03-20 11:59
Publication Fee Transferred	2025-03-03 12:20
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-05-28 01:44
Publish the Manuscript Online	2025-06-03 08:25

ISSN	2150-5349 (online)
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Probiotics and prebiotics in the treatment of functional constipation in the elderly individuals
Manuscript Source	Unsolicited Manuscript
All Author List	Li Xu, Jian-Tang Guo, Jing Zhao, Ming-He Liu and Chen Mo
Funding Agency and Grant Number
Corresponding Author	Chen Mo, MD, PhD, Professor, Department of Gerontology, The Third Medical Center of PLA General Hospital, No. 69 Beijing Yongding Road, Haidian District, Beijing 100039, China. mchen@sohu.com
Key Words	Functional constipation; Elderly; Gut microbiota; Microbiota dysbiosis; Gut-brain axis; Probiotics; Prebiotic
Core Tip	Probiotics and prebiotics may play a significant role in managing functional constipation (FC) in elderly individuals by modulating gut microbiota and alleviating symptoms. The interplay between gut microbiota dysbiosis and the gut-brain axis further complicates FC, necessitating a multifaceted treatment approach that includes microecological agents to enhance gut health and improve the quality of life for older adults. Recent studies have highlighted the potential use of probiotics and prebiotics in managing FC, particularly in the elderly individuals.
Publish Date	2025-06-03 08:25
Citation	<p>Xu L, Guo JT, Zhao J, Liu MH, Mo C. Probiotics and prebiotics in the treatment of functional constipation in the elderly individuals. <i>World J Gastrointest Pharmacol Ther</i> 2025; 16(2): 105242</p>
URL	https://www.wjgnet.com/2150-5349/full/v16/i2/105242.htm
DOI	https://dx.doi.org/10.4292/wjgpt.v16.i2.105242

Full Article (PDF)	WJGPT-16-105242-with-cover.pdf
Manuscript File	105242_Auto_Edited_085941.docx
Answering Reviewers	105242-answering-reviewers.pdf
Audio Core Tip	105242-audio.mp3
Conflict-of-Interest Disclosure Form	105242-conflict-of-interest-statement.pdf
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Non-Native Speakers of English Editing Certificate	105242-non-native-speakers.pdf
Peer-review Report	105242-peer-reviews.pdf
Scientific Misconduct Check	105242-scientific-misconduct-check.png
Scientific Editor Work List	105242-scientific-editor-work-list.pdf
CrossCheck Report	105242-crosscheck-report.pdf