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5/30/2025 3:54:39 AM | Browse: 47 | Download: 51
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Received |
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2025-03-09 07:13 |
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Peer-Review Started |
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2025-03-09 07:14 |
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To Make the First Decision |
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Return for Revision |
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2025-03-19 09:55 |
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Revised |
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2025-03-31 19:04 |
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Second Decision |
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2025-04-09 02:40 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-04-09 08:59 |
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Articles in Press |
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2025-04-09 08:59 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2025-04-16 04:06 |
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Typeset the Manuscript |
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2025-05-27 03:00 |
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Publish the Manuscript Online |
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2025-05-30 02:05 |
ISSN |
1949-8454 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Neurosciences |
Manuscript Type |
Minireviews |
Article Title |
Stem cell therapy for Parkinson’s disease: A new hope for neural regeneration
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Manuscript Source |
Invited Manuscript |
All Author List |
Yasmin Garkani Mokhtari, Irene Varnava, Kosmas Kyrgiannis, Vasiliki Ampatsidou and Dimitrios Giakoumettis |
Funding Agency and Grant Number |
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Corresponding Author |
Dimitrios Giakoumettis, Consultant, MD, PhD, Post Doctoral Researcher, Department of Neurosurgery, Agios Savvas, General Anticancer Oncological Hospital, 171 Alexandras Avenue, Athens 11522, Attikí, Greece. dgiakoumettis@gmail.com |
Key Words |
Stem cells; Parkinson’s disease; Induced pluripotent stem cells; Human pluripotent stem cells; Adult stem cells |
Core Tip |
Parkinson’s disease (PD) is a neurodegenerative disorder caused by the loss of dopamine neurons in the substantia nigra. To date, there is no treatment for PD while stem cell therapy represents a new therapeutic approach to restore lost neural function. The manuscript focuses on the potential of stem cell therapy, particularly induced pluripotent stem cells (iPSCs) and human pluripotent stem cells, in treating PD, offering potential for neuronal replacement and restoration of brain function. iPSCs are derived from reprogramming adult cells, which are genetically compatible and cause reduced immune rejection, overcoming ethical concerns associated with embryonic stem cells. |
Publish Date |
2025-05-30 02:05 |
Citation |
<p>Mokhtari YG, Varnava I, Kyrgiannis K, Ampatsidou V, Giakoumettis D. Stem cell therapy for Parkinson’s disease: A new hope for neural regeneration. <i>World J Biol Chem</i> 2025; 16(2): 106850</p> |
URL |
https://www.wjgnet.com/1949-8454/full/v16/i2/106850.htm |
DOI |
https://dx.doi.org/10.4331/wjbc.v16.i2.106850 |
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