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12/17/2025 7:16:34 AM | Browse: 20 | Download: 78
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Received |
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2025-06-10 16:03 |
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Peer-Review Started |
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2025-06-10 16:03 |
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First Decision by Editorial Office Director |
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2025-07-04 09:06 |
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Return for Revision |
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2025-07-04 09:06 |
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Revised |
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2025-07-09 11:51 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-10-20 03:00 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-10-20 07:55 |
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Articles in Press |
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2025-10-20 07:55 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-12-08 02:32 |
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Publish the Manuscript Online |
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2025-12-17 06:45 |
| ISSN |
2218-5836 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Orthopedics |
| Manuscript Type |
Observational Study |
| Article Title |
Efficacy of intradiscal autologous platelet-rich plasma injection in chronic lumbar disc prolapse: A quasi-experimental study
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Prabu Mounisamy, Anirudh Dwajan, Dibyajyoti Sahoo, Naveen Jeyaraman, Sathish Muthu, Swaminathan Ramasubramanian and Madhan Jeyaraman |
| Funding Agency and Grant Number |
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| Corresponding Author |
Madhan Jeyaraman, MD, PhD, Researcher, Department of Orthopaedics, ACS Medical College and Hospital, Dr MGR Educational and Research Institute, Velappanchavadi, Chennai 600077, Tamil Nadu, India. madhanjeyaraman@gmail.com |
| Key Words |
Lumbar disc herniation; Chronic low back pain; Platelet-rich plasma; Intradiscal injection; Functional outcome; Visual Analogue Scale; Functional Rating Index; Regenerative therapy |
| Core Tip |
Intradiscal autologous platelet-rich plasma injection significantly reduced pain and improved function in chronic lumbar disc prolapse patients unresponsive to physiotherapy, achieving outcomes comparable to physiotherapy responders at 3 and 6 weeks. While these preliminary findings are encouraging, the brief 6-week follow-up period precludes assessment of durability, and larger studies with extended follow-up are essential to establish long-term efficacy, evaluate potential structural effects and safety. |
| Publish Date |
2025-12-17 06:45 |
| Citation |
Mounisamy P, Dwajan A, Sahoo D, Jeyaraman N, Muthu S, Ramasubramanian S, Jeyaraman M. Efficacy of intradiscal autologous platelet-rich plasma injection in chronic lumbar disc prolapse: A quasi-experimental study. World J Orthop 2025; 16(12): 110530 |
| URL |
https://www.wjgnet.com/2218-5836/full/v16/i12/110530.htm |
| DOI |
https://dx.doi.org/10.5312/wjo.v16.i12.110530 |
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