| ISSN |
2308-3840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cardiac & Cardiovascular Systems |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Pulsed field vs cryoballoon ablation: A meta-analysis with Hartung–Knapp, subgroup, and meta-regression analyses
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Mirza Muhammad Hadeed Khawar, Sanjar Odilov, Uzer Memon, Huijing Sun, Sulaiman Samee, Prasansa Dhakal, Anwita Mishra, Sumaiya Khan, Moosa Feroze Tarar, Muhammad Iqbal and Asraf Hussain |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Asraf Hussain, Associate Professor, DM, MD, Department of Cardiology, Chitwan Medical College, Bharatpur-10, Chitwan, Bharatpur 33915, Nepal. drasrafcardiology@gmail.com |
| Key Words |
Atrial fibrillation; Pulmonary vein isolation; Pulsed field ablation; Cryoballoon ablation; Meta-analysis; Catheter ablation |
| Core Tip |
This meta-analysis synthesizes data from comparative studies to evaluate pulsed field ablation (PFA) vs cryoballoon ablation for atrial fibrillation. Beyond standard pooled estimates, advanced analyses including Hartung-Knapp adjustment, subgroup, and meta-regression techniques were applied to enhance robustness. PFA demonstrated significantly shorter procedure times and lower phrenic nerve palsy risk, with comparable efficacy and safety profiles to cryoballoon ablation. These findings highlight PFA’s procedural advantages and support its growing clinical adoption, while underscoring the need for large-scale randomized trials. |
| Publish Date |
2025-12-18 05:53 |
| Citation |
Khawar MMH, Odilov S, Memon U, Sun H, Samee S, Dhakal P, Mishra A, Khan S, Tarar MF, Iqbal M, Hussain A. Pulsed field vs cryoballoon ablation: A meta-analysis with Hartung–Knapp, subgroup, and meta-regression analyses. World J Meta-Anal 2025; 13(4): 115195 |
| URL |
https://www.wjgnet.com/2308-3840/full/v13/i4/115195.htm |
| DOI |
https://dx.doi.org/10.13105/wjma.v13.i4.115195 |
