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6/16/2026 9:18:41 AM | Browse: 1 | Download: 0
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2026-03-03 03:17 |
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2026-03-26 10:18 |
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2026-04-23 02:37 |
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Typeset the Manuscript |
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2026-06-05 01:21 |
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2026-06-16 09:18 |
| ISSN |
2150-5330 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Liver stiffness at baseline as a marker of hepatocellular carcinoma in cirrhosis: A matched analysis
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Varun Mehta, Manjeet Kumar Goyal, Yogesh Kumar Gupta, Abhinav Gupta, Manisha Khubber, Tanisha Sehgal, Prabhav Mehta and Omesh Goyal |
| Funding Agency and Grant Number |
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| Corresponding Author |
Manjeet Kumar Goyal, Department of Internal Medicine, Cleveland Clinic Akron General Hospital, Akron, Ohio, USA, 1, Akron General Avenue, AKron, Akron, OH 44308, United States. manjeetgoyal@gmail.com |
| Key Words |
Hepatocellular carcinoma; Liver cirrhosis; Liver fibrosis; Liver stiffness; Elastography; Liver stiffness measurement; Hepatocellular carcinoma; Cirrhosis; Risk stratification; Portal hypertension |
| Core Tip |
Hepatocellular carcinoma (HCC) surveillance in cirrhosis remains imperfect, with a substantial proportion of tumors detected at advanced stages despite guideline-recommended ultrasound-based screening. In this matched case–control study, baseline liver stiffness measurement (LSM) assessed by transient elastography independently stratified HCC risk among patients with established cirrhosis. Higher LSM values were strongly associated with HCC, with excellent discriminative performance and a clinically relevant threshold identifying patients at particularly high risk. These findings support the integration of LSM into HCC risk stratification frameworks and suggest that liver stiffness–guided, individualized surveillance strategies may improve early detection in cirrhosis. |
| Publish Date |
2026-06-16 09:18 |
| Citation |
Mehta V, Goyal MK, Gupta YK, Gupta A, Khubber M, Sehgal T, Mehta P, Goyal O. Liver stiffness at baseline as a marker of hepatocellular carcinoma in cirrhosis: A matched analysis. World J Gastrointest Pathophysiol 2026; 17(2): 120603
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| URL |
https://www.wjgnet.com/2150-5330/full/v17/i2/120603.htm |
| DOI |
https://doi.org/10.4291/wjgp.v17.i2.120603 |
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