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6/16/2026 9:18:41 AM | Browse: 1 | Download: 0
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Received |
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2026-04-09 03:40 |
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2026-04-09 03:40 |
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2026-04-21 09:55 |
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2026-04-21 09:55 |
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2026-04-30 04:32 |
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2026-05-13 02:42 |
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2026-05-13 08:21 |
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Articles in Press |
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2026-05-13 08:21 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-06-10 10:55 |
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Publish the Manuscript Online |
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2026-06-16 09:18 |
| ISSN |
2150-5330 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Appendix in ulcerative colitis pathogenesis and therapy: An updated narrative review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Omar AbdelGhani, Sherreen Elhariri, Payal Bhatnagar, Htar Htar Aung, Mohamed Abdel Wahab and Nabil Eid |
| Funding Agency and Grant Number |
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| Corresponding Author |
Nabil Eid, Associate Professor, MD, PhD, Department of Human Biology, School of Medicine, IMU University, Bukit Jalil, Kuala Lumpur 57000, Malaysia. nabilsaleheid@imu.edu.my |
| Key Words |
Ulcerative colitis; Therapeutic appendectomy; Autophagy; Xenophagy; Immune dysregulation |
| Core Tip |
Recent clinical studies indicate the potential of the appendix as an immunological and microbial niche in ulcerative colitis pathogenesis. Induction of immune dysregulation and acceleration of inflammation are associated with autophagy dysfunction in colonic cells, and possibly the appendix. Current evidence suggests the potential of appendectomy as an adjunctive therapeutic strategy, improving remission in selected patients. |
| Publish Date |
2026-06-16 09:18 |
| Citation |
AbdelGhani O, Elhariri S, Bhatnagar P, Aung HH, Abdel Wahab M, Eid N. Appendix in ulcerative colitis pathogenesis and therapy: An updated narrative review. World J Gastrointest Pathophysiol 2026; 17(2): 122072
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| URL |
https://www.wjgnet.com/2150-5330/full/v17/i2/122072.htm |
| DOI |
https://doi.org/10.4291/wjgp.v17.i2.122072 |
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