ISSN |
1949-8462 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Cardiac & Cardiovascular Systems |
Manuscript Type |
Observational Study |
Article Title |
Markers of inflammation and cardiovascular disease in recently diagnosed celiac disease patients
|
Manuscript Source |
Invited Manuscript |
All Author List |
Walter F Tetzlaff, Tomás Meroño, Martin Menafra, Maximiliano Martin, Eliana Botta, Maria D Matoso, Patricia Sorroche, Juan A De Paula, Laura E Boero and Fernando Brites |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
CONICET |
PIP 11220110100516 |
University of Buenos Aires |
UBACyT 20020150100054BA |
|
Corresponding Author |
Laura E Boero, PhD, Department of Clinical of Biochemistry, School of Pharmacy and Biochemistry, University of Buenos Aires, INFIBIOC, CONICET, Junín 956 (1113), Buenos Aires C1113AAD, Argentina. laura.boero@hotmail.com |
Key Words |
Inflammation; Cardiovascular disease; High density lipoprotein-cholesterol; Lipoproteins; Celiac disease |
Core Tip |
Given that data about the presence of metabolic alterations and atherogenic risk factors in celiac disease are scarce and contradictory, we aimed to investigate carbohydrate metabolism, lipoprotein profile and inflammatory status in patients with celiac disease (CD). Patients presented higher insulin levels, Homeostasis Model Assessment-Insulin Resistance index, apo B/apo A-I ratio and High-sensitivity C reactive protein concentration, as well as lower Quantitative Sensitive Check index index, high density lipoprotein-cholesterol and apo A-I levels in comparison with sex and aged-matched healthy controls. Persistence of these alterations through long periods of time in a chronic pathologic condition, as it is the case with CD, would constitute a high risk of developing atherosclerotic cardiovascular disease. |
Publish Date |
2017-05-20 11:08 |
Citation |
Tetzlaff WF, Meroño T, Menafra M, Martin M, Botta E, Matoso MD, Sorroche P, De Paula JA, Boero LE, Brites F. Markers of inflammation and cardiovascular disease in recently diagnosed celiac disease patients. World J Cardiol 2017; 9(5): 448-456 |
URL |
http://www.wjgnet.com/1949-8462/full/v9/i5/448.htm |
DOI |
http://dx.doi.org/10.4330/wjc.v9.i5.448 |