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5/23/2017 8:36:14 AM | Browse: 860 | Download: 861
Publication Name World Journal of Gastroenterology
Manuscript ID 32086
Country/Territory Italy
Received
2016-12-24 17:05
Peer-Review Started
2016-12-28 17:55
To Make the First Decision
2017-02-09 15:04
Return for Revision
2017-02-14 10:20
Revised
2017-02-28 17:52
Second Decision
2017-04-11 15:50
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-04-13 11:04
Articles in Press
2017-04-13 11:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-04-24 18:03
Publish the Manuscript Online
2017-05-20 12:26
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Relationship between adipose tissue dysfunction, vitamin D deficiency and the pathogenesis of non-alcoholic fatty liver disease
Manuscript Source Invited Manuscript
All Author List Flavia A Cimini, Ilaria Barchetta, Simone Carotti, Laura Bertoccini, Marco G Baroni, Umberto Vespasiani-Gentilucci, Maria Gisella Cavallo and Sergio Morini
Funding Agency and Grant Number
Corresponding Author Sergio Morini, MD, Professor, Laboratory of Microscopic and Ultrastructural Anatomy (CIR), Faculty of Medicine, University Campus Bio-Medico, Via Alvaro Del Portillo, 21, 00128 Rome, Italy. s.morini@unicampus.it
Key Words Adipose tissue dysfunction; Vitamin D; Non-alcoholic fatty liver disease; Steatosis; Non-alcoholic steatohepatitis; Obesity; Adipokines
Core Tip Obesity-associated chronic low-grade in­flammation plays a pivotal role in the development of non-alcoholic fatty liver disease (NAFLD). Vitamin D deficiency is associated with both obesity and NAFLD, and its anti-inflammatory and immune-modulatory properties provided plausible mechanisms by which hypovitaminosis D may link adipose tissue dysfunction and NAFLD. Animal studies showed beneficial effect of vitamin D supplementation on systemic inflammation and NAFLD, but these data are not confirmed by the results of clinical trials so far conducted in humans.
Publish Date 2017-05-20 12:26
Citation Cimini FA, Barchetta I, Carotti S, Bertoccini L, Baroni MG, Vespasiani-Gentilucci U, Cavallo MG, Morini S. relationship between adipose tissue dysfunction, vitamin D deficiency and the pathogenesis of non-alcoholic fatty liver disease. World J Gastroenterol 2017; 23(19): 3407-3417
URL http://www.wjgnet.com/1007-9327/full/v23/i19/3407.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i19.3407
Full Article (PDF) WJG-23-3407.pdf
Full Article (Word) WJG-23-3407.doc
Manuscript File 32086-Review.docx
Answering Reviewers 32086-Answering reviewers.pdf
Audio Core Tip 32086-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 32086-Conflict-of-interest statement.pdf
Copyright License Agreement 32086-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 32086-Language Certificate.pdf
Peer-review Report 32086-Peer-review(s).pdf
Scientific Misconduct Check 32086-Scientific misconduct check.pdf
Scientific Editor Work List 32086-Scientific editor work list.pdf