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9/15/2017 8:06:21 AM | Browse: 515 | Download: 1022
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Received |
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2017-04-28 08:43 |
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Peer-Review Started |
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2017-04-28 14:12 |
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To Make the First Decision |
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2017-05-23 00:48 |
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Return for Revision |
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2017-05-23 09:36 |
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Revised |
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2017-06-21 04:05 |
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Second Decision |
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2017-06-29 08:32 |
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Accepted by Journal Editor-in-Chief |
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2017-06-29 15:02 |
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Accepted by Company Editor-in-Chief |
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2017-07-10 03:00 |
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Articles in Press |
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2017-07-10 03:00 |
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Publication Fee Transferred |
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2017-08-16 05:57 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-09-14 06:03 |
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Publish the Manuscript Online |
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2017-09-15 05:43 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Regional differences in genetic susceptibility to non-alcoholic liver disease in two distinct Indian ethnicities
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Govardhan Bale, Avanthi Urmila Steffie, Vishnubhotla Venkata Ravi Kanth, Padaki Nagaraja Rao, Mithun Sharma, Mitnala Sasikala and Duvvur Nageshwar Reddy |
| Funding Agency and Grant Number |
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| Corresponding Author |
Vishnubhotla Venkata Ravi Kanth, Doctor, Asian Healthcare Foundation, 6-3-661, Somajiguda, Hyderabad 500082, India. drravikanth@aigindia.net |
| Key Words |
Transmembrane 6 superfamily 2; Patatin-like phospholipase domain-containing protein 3; Fatty infiltration; Genetic susceptibility; Ethnicity; Non-alcoholic fatty liver disease; Cirrhosis; Single nucleotide polymorphism |
| Core Tip |
Non-alcoholic fatty liver disease has become the leading cause of liver damage contributing to considerable mortality. The spectrum spans from simple steatosis, through non alcoholic steatohepatitis, fibrosis, cirrhosis and finally to hepatocellular carcinoma. Genetic variants have now been recognized to contribute to a substantial extent to the onset of the disease. Reliable genetic markers that confer susceptibility to the disease have to be identified for better management of the disease. Identification of at risk individuals at a younger age by screening for genetic susceptibility will aid in better management by early interventions and lifestyle changes. This study identified regional differences and ethnicity based genetic susceptibility for non-alcoholic liver disease. |
| Publish Date |
2017-09-15 05:43 |
| Citation |
Bale G, Steffie AU, Ravi Kanth VV, Rao PN, Sharma M, Sasikala M, Reddy DN. Regional differences in genetic susceptibility to non-alcoholic liver disease in two distinct Indian ethnicities. World J Hepatol 2017; 9(26): 1101-1107 |
| URL |
http://www.wjgnet.com/1948-5182/full/v9/i26/1101.htm |
| DOI |
http://dx.doi.org/10.4254/wjh.v9.i26.1101 |
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