| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, and build upon this work non-commercially and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/bync/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Clinically diagnosed late-onset fulminant Wilson disease without cirrhosis: A case report
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Takahiro Amano, Tokuhiro Matsubara, Tsutomu Nishida, Hiromi Shimakoshi, Akiyoshi Shimoda, Aya Sugimoto, Kei Takahashi, Kaori Mukai, Masashi Yamamoto, Shiro Hayashi, Sachiko Nakajima, Koji Fukui and Masami Inada |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Tokuhiro Matsubara, MD, PhD, Department of Gastroenterology and Hepatology, Toyonaka Municipal Hospital, 4-14-1 Shibahara, Toyonaka, Osaka 560-8565, Japan. tmatsubara@chp.toyonaka.osaka.jp |
| Key Words |
Wilson disease; Fulminant hepatitis; Late-onset; Liver cirrhosis; Copper |
| Core Tip |
A 64-year-old woman was referred to our hospital with hepatopathy. After admission, she developed hepatic encephalopathy. Laboratory findings revealed that serum ceruloplasmin levels were reduced, serum and urinary copper levels were greatly elevated and Wilson disease (WD)-specific routine tests were positive. She was diagnosed with fulminant WD based on the American Association for the Study of Liver Disease practice guidelines. At autopsy, the liver did not show a bridging pattern of fibrosis suggestive of chronic liver injury. Here, we present the first case of a patient with clinically diagnosed late-onset fulminant WD without cirrhosis. |
| Publish Date |
2018-01-14 05:07 |
| Citation |
Amano T, Matsubara T, Nishida T, Shimakoshi H, Shimoda A, Sugimoto A, Takahashi K, Mukai K, Yamamoto M, Hayashi S, Nakajima S, Fukui K, Inada M. Clinically diagnosed late-onset fulminant Wilson’s disease without cirrhosis: A case report. World J Gastroenterol 2018; 24(2): 290-296 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i2/290.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i2.290 |
