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9/4/2018 3:37:25 AM | Browse: 723 | Download: 718
Publication Name World Journal of Stem Cells
Manuscript ID 39155
Country/Territory Romania
Received
2018-03-29 23:42
Peer-Review Started
2018-03-30 07:40
To Make the First Decision
2018-04-23 05:41
Return for Revision
2018-04-25 06:12
Revised
2018-07-11 19:13
Second Decision
2018-07-13 08:56
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-07-16 05:35
Articles in Press
2018-07-16 05:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-08-27 07:59
Publish the Manuscript Online
2018-08-27 10:18
ISSN 1948-0210 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Review
Article Title Stem cell-derived exosomes - an emerging tool for myocardial regeneration
Manuscript Source Invited Manuscript
All Author List Erzsebet Lazar, Theodora Benedek, Szilamer Korodi, Nora Rat, Jocelyn Lo and Imre Benedek
Funding Agency and Grant Number
Funding Agency Grant Number
Romanian Ministry of European Funds, the Romanian Government and the European Union 103544/2016 - PLaqueIMAGE
Corresponding Author Theodora Benedek, MD, PhD, Full Professor, Department of Internal Medicine, Clinic of Cardiology, University of Medicine and Pharmacy Tirgu Mures, Gheorghe Marinescu Street No. 38, Tirgu Mures 540136, Romania. theodora.benedek@gmail.com
Key Words Acute myocardial infarction; Exosome; Stem cell; Cardiac regeneration; Cardiovascular diseases
Core Tip Regenerative therapy represents the ultimate goal for restoring the function of damaged myocardium by stimulating the regeneration of infarcted tissue. Exosomes are small microvesicles released by living cells that act as miRNA nanocarriers, and exosomes can stimulate and modulate cellular proliferation and regeneration. Elevated exosome levels have been detected in human plasma in various cardiovascular diseases. Furthermore, myocardium-derived exosomes are potentially associated with myocardial healing. Given their paracrine properties, myocardium-derived exosomes have been proposed as a potential therapeutic option for myocardial regeneration. This review discusses the emerging roles of exosomes as candidate biomarkers and innovative therapies for cardiac regeneration.
Publish Date 2018-08-27 10:18
Citation Lazar E, Benedek T, Korodi S, Rat N, Lo J, Benedek I. Stem cell-derived exosomes - an emerging tool for myocardial regeneration. World J Stem Cells 2018; 10(8): 106-115
URL http://www.wjgnet.com/1948-0210/full/v10/i8/106.htm
DOI http://dx.doi.org/10.4252/wjsc.v10.i8.106
Full Article (PDF) WJSC-10-106.pdf
Full Article (Word) WJSC-10-106.doc
Manuscript File 39155-Review.docx
Answering Reviewers 39155-Answering reviewers.pdf
Audio Core Tip 39155-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 39155-Conflict-of-interest statement.pdf
Copyright License Agreement 39155-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 39155-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 39155-Language certificate.pdf
Peer-review Report 39155-Peer-review(s).pdf
Scientific Misconduct Check 39155-Scientific misconduct check.pdf
Scientific Editor Work List 39155-Scientific editor work list.pdf