Publication Name	World Journal of Gastroenterology
Manuscript ID	42408
Country	Monaco

Received	2018-09-29 02:44
Peer-Review Started	2018-09-29 07:48
To Make the First Decision	2018-11-08 06:10
Return for Revision	2018-11-14 06:51
Revised	2019-03-21 10:13
Second Decision	2019-03-29 10:25
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-03-30 00:51
Articles in Press	2019-03-30 00:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-05-14 00:35
Publish the Manuscript Online	2019-05-14 07:58

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an inhouse editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution non Commercial (CC BY-NC4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is propely cited and the use is non-commercial. See: htpp//cretivecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Diversity of Saccharomyces boulardii CNCM I-745 mechanisms of action against intestinal infections
Manuscript Source	Unsolicited Manuscript
All Author List	Patrick Rampal and Dorota Czerucka
Funding Agency and Grant Number
Corresponding Author	Dorota Czerucka, PhD, Senior Researcher, Senior Scientist, Department of Human Health, Division of Ecosystems and Immunity, Center Scientific of Monaco, 8 Quai Antoine 1er, Monaco MC98000, Monaco. dczerucka@centrescientifique.mc
Key Words	Saccharomyces boulardii CNCM I-745; Probiotics; Yeast; Intestinal infection; Mechanism
Core Tip	The efficacy of lyophilized probiotic yeast Saccharomyces boulardii CNCM I-745 was clinically demonstrated with controlled studies of intestinal infections associated with antibiotics and acute diarrhea in children. This review summerizes scientific data describing the mechanism of Saccharomyces boulardii protection against infection and emphazises the diversity of potential mechanism of action that this probiotic yeast can have against pathogenic microorganisms. More recently, effects on the recovery of the intestinal microbiota as well as on the immune system have been demonstrated, thus opening up a new therapeutic potential of this yeast.
Publish Date	2019-05-14 07:58
Citation	Czerucka D, Rampal P. Diversity of Saccharomyces boulardii CNCM I-745 mechanisms of action against intestinal infections. World J Gastroenterol 2019; 25(18): 2188-2203
URL	https://www.wjgnet.com/1007-9327/full/v25/i18/2188.htm
DOI	https://dx.doi.org/10.3748/wjg.v25.i18.2188

Full Article (PDF)	WJG-25-2188.pdf
Full Article (Word)	WJG-25-2188.docx
Manuscript File	42408-Review.docx
Answering Reviewers	42408-Answering reviewers.pdf
Audio Core Tip	42408-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	42408-Conflict-of-interest statement.pdf
Copyright License Agreement	42408-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	42408-Language certificate.pdf
Peer-review Report	42408-Peer-review(s).pdf
Scientific Misconduct Check	42408-Scientific misconduct check.pdf
Scientific Editor Work List	42408-Scientific editor work list.pdf