| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Physiology |
| Manuscript Type |
Review |
| Article Title |
Underlying effects of apoptosis on liver aging
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Shao-Jie Hu, Sha-Sha Jiang, Jin Zhang, Dan Luo, Bo Yu, Liang-Yan Yang, Hua-Hua Zhong, Mei-Wen Yang, Li-Yu Liu, Fen-Fang Hong and Shu-Long Yang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81660151 |
| National Natural Science Foundation of China |
81660751 |
| National Natural Science Foundation of China |
81260504 |
| Science Foundation of the Science Commission of Jiang Xi Province in China |
20161BBG70067 |
| Jiangxi Provincial Natural Science Foundation of China |
20171BAB205085 |
|
| Corresponding Author |
Shu-Long Yang, PhD, Professor, Department of Physiology, Department of Physiology, College of Medicine, Nanchang University, Nanchang 310006, Jiangxi Province, China. slyang@ncu.edu.cn |
| Key Words |
Apoptosis; Liver aging; Oxidative stress; Caloric restriction; Cirrhosis |
| Core Tip |
Aging liver exhibits functional and morphological changes. Apoptosis eliminates transformed abnormal cells but promotes age-related liver diseases, such as nonalcoholic fatty liver disease, liver fibrosis, cirrhosis, and liver cancer. Apoptosis including intrinsic and extrinsic pathways has protective and deleterious effects on liver aging. The occurrence, development, and treatment of age-related liver diseases correlate highly with liver aging and apoptosis. The paper elaborates the underlying effects of apoptosis on liver aging. |
| Publish Date |
2019-03-26 03:26 |
| Citation |
Hu SJ, Jiang SS, Zhang J, Luo D, Yu B, Yang LY, Zhong HH, Yang MW, Liu LY, Hong FF, Yang SL. Underlying effects of apoptosis on liver aging. World J Clin Cases2019; 7(6): 691-704 |
| URL |
https://www.wjgnet.com/2307-8960/full/v7/i6/691.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v7.i6.691 |
