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3/26/2020 1:57:21 PM | Browse: 528 | Download: 514
Publication Name World Journal of Clinical Cases
Manuscript ID 53824
Country/Territory Italy
Received
2019-12-30 17:10
Peer-Review Started
2019-12-30 17:15
To Make the First Decision
2020-02-04 09:21
Return for Revision
2020-02-11 00:43
Revised
2020-02-14 18:02
Second Decision
2020-03-04 10:01
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-03-05 06:42
Articles in Press
2020-03-05 06:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-03-17 02:03
Publish the Manuscript Online
2020-03-26 03:19
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research & Experimental
Manuscript Type Review
Article Title Microbiota-gut-brain axis and its affect inflammatory bowel disease: Pathophysiological concepts and insights for clinicians
Manuscript Source Invited Manuscript
All Author List Emanuele Sinagra, Erika Utzeri, Gaetano Cristian Morreale, Carlo Fabbri, Fabio Pace and Andrea Anderloni
Funding Agency and Grant Number
Corresponding Author Emanuele Sinagra, MD, PhD, Doctor, Gastroenterology and Endoscopy Unit, Fondazione Istituto Giuseppe Giglio, Contrada Pietra Pollastra Pisciotto, Cefalù 90015, Italy. emanuelesinagra83@googlemail.com
Key Words Irritable bowel syndrome; Inflammatory bowel disease; Gut-brain axis; Therapy; ;
Core Tip The complex interplay between gut microbiota and the brain, and vice versa, has recently become not only the focus of neuroscience, but also the start point for research regarding many diseases such as inflammatory bowel diseases (IBD) and irritable bowel syndrome. The bi-directional interaction between gut microbiota and the brain is not completely understood. Nonetheless, there is increasing evidence arising from animal and human studies that show how this intricate relationship may contribute to the pathogenesis of IBD, with consequent important implications for the possibility to improve the clinical outcomes of the diseases themselves by acting on the different components of this axis. With the emergence of precision medicine, strategies in which patients with IBD might be categorized other than for standard gut symptom complexes could offer the opportunity to tailor therapies to individual patients.
Publish Date 2020-03-26 03:19
Citation Sinagra E, Utzeri E, Morreale GC, Fabbri C, Pace F, Anderloni A. Microbiota-gut-brain axis and its affect inflammatory bowel disease: Pathophysiological concepts and insights for clinicians. World J Clin Cases 2020; 8(6): 1013-1025
URL https://www.wjgnet.com/2307-8960/full/v8/i6/1013.htm
DOI https://dx.doi.org/10.12998/wjcc.v8.i6.1013
Full Article (PDF) WJCC-8-1013.pdf
Full Article (Word) WJCC-8-1013.docx
Manuscript File 53824-Review.docx
Answering Reviewers 53824-Answering reviewers.pdf
Audio Core Tip 53824-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 53824-Conflict-of-interest statement.pdf
Copyright License Agreement 53824-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 53824-Language certificate.pdf
Peer-review Report 53824-Peer-review(s).pdf
Scientific Misconduct Check 53824-Scientific misconduct check.pdf
Scientific Editor Work List 53824-Scientific editor work list.pdf