| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Review |
| Article Title |
One disease, many faces-typical and atypical presentations of SARS-CoV-2 infection-related COVID-19 disease
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Cyriac Abby Philips, Narain Mohan, Rizwan Ahamed, Sandeep Kumbar, Sasidharan Rajesh, Tom George, Meera Mohanan and Philip Augustine |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Cyriac Abby Philips, MBBS, MD, Consultant Physician-Scientist, The Liver Unit and Monarch, Cochin Gastroenterology Group, Ernakulam Medical Center, NH Bypass, Palarivattom, Cochin 682025, Kerala, India. abbyphilips@gmail.com |
| Key Words |
Adult respiratory distress syndrome; Sepsis; COVID-19; SARS-Cov-2; World health organization; Centers for disease control |
| Core Tip |
The novel severe acute respiratory syndrome-coronavirus-2 virus causing coronavirus disease 2019 (COVID-19) pandemic can present with typical or atypical symptoms and signs. Classical clinical presentation includes fever, cough, and sore throat with or without other associated symptoms such as anorexia, nausea, and lethargy in the presence or absence of pneumonia, which is commonly noticed as ground-glass opacities on chest imaging. Gastrointestinal and hepatic involvement is very non-specific, but diarrhoea is known to predominate in some patients in the absence of typical symptoms and signs. Other systems involvement include electrographic abnormalities associated with clinical events such as syncope, viral myocarditis related cardiac failure, meningoencephalitis, and acute inflammatory demyelinating polyneuropathy, a dermatological presentation with diffuse urticaria or viral exanthem, smell and taste dysfunction and local and systemic venous thromboembolism. Other rare presentations include keratoconjunctivitis and otitis media. Physicians caring for, and battling on the frontlines against COVID-19 should be aware of the “many faces” that this singular disease can present with, for timely diagnosis and prompt initiation of best treatment options. |
| Publish Date |
2020-09-22 03:17 |
| Citation |
Philips CA, Mohan N, Ahamed R, Kumbar S, Rajesh S, George T, Mohanan M, Augustine P. One disease, many faces-typical and atypical presentations of SARS-CoV-2 infection related COVID-19 disease. World J Clin Cases 2020; 8(18): 3956-3970 |
| URL |
https://www.wjgnet.com/2307-8960/full/v8/i18/3956.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v8.i18.3956 |
