Publication Name	World Journal of Stem Cells
Manuscript ID	59741
Country	Brazil

Received	2020-09-26 03:12
Peer-Review Started	2020-09-26 03:13
To Make the First Decision
Return for Revision	2020-11-03 21:50
Revised	2020-12-15 21:21
Second Decision	2021-01-05 02:50
Accepted by Journal Editor-in-Chief	2021-01-06 04:22
Accepted by Company Editor-in-Chief	2021-01-15 19:12
Articles in Press	2021-01-15 19:12
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-01-22 01:12
Typeset the Manuscript	2021-02-22 06:56
Publish the Manuscript Online	2021-02-24 03:29

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Orthopedics
Manuscript Type	Minireviews
Article Title	Platelet-rich plasma vs bone marrow aspirate concentrate: An overview of mechanisms of action and orthobiologic synergistic effects
Manuscript Source	Unsolicited Manuscript
All Author List	José Fábio Santos Duarte Lana, Lucas Furtado da Fonseca, Rafael da Rocha Macedo, Tomas Mosaner, William Murrell, Ashok Kumar, Joseph Purita and Marco Antonio Percope de Andrade
Funding Agency and Grant Number
Corresponding Author	José Fábio Santos Duarte Lana, MD, Chief Doctor, Surgeon, Department of Orthopedics, The Bone and Cartilage Institute, 1386 Presidente Kennedy Avenue, Indaiatuba 13334-170, SP, Brazil. josefabiolana@gmail.com
Key Words	Orthobiologics; Platelet-rich plasma; Bone-marrow aspirate; Regenerative medicine; Musculoskeletal diseases; Stem cells
Core Tip	Degenerative musculoskeletal disorders are one of the top causes of pain and disability in the adult population. The use of certain analgesics delivers short term results but do not address the etiological source of pain and disability. The demand for musculoskeletal tissue regeneration has led to an alternative approach referred to as orthobiologics, which is based on cellular and molecular components capable of promoting tissue repair. Platelet-rich plasma and bone marrow aspirate concentrate are popular orthobiologic products that may work synergistically in order to enhance the treatment of musculoskeletal conditions.
Publish Date	2021-02-24 03:29
Citation	Lana JFSD, da Fonseca LF, Macedo RDR, Mosaner T, Murrell W, Kumar A, Purita J, de Andrade MAP. Platelet-rich plasma vs bone marrow aspirate concentrate: An overview of mechanisms of action and orthobiologic synergistic effects. World J Stem Cells 2021; 13(2): 155-167
URL	https://www.wjgnet.com/1948-0210/full/v13/i2/155.htm
DOI	https://dx.doi.org/10.4252/wjsc.v13.i2.155

Full Article (PDF)	WJSC-13-155.pdf
Full Article (Word)	WJSC-13-155.docx
Manuscript File	59741-Review-FilipodiaCL.docx
Answering Reviewers	59741-Answering reviewers.pdf
Audio Core Tip	59741-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	59741-Conflict-of-interest statement.pdf
Copyright License Agreement	59741-Copyright license agreement.pdf
Peer-review Report	59741-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	59741-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	59741-Bing-Yan JP-1.png
Scientific Misconduct Check	59741-Scientific misconduct check.pdf
Scientific Editor Work List	59741-Scientific editor work list.pdf