Publication Name	World Journal of Gastroenterology
Manuscript ID	61954
Country	Argentina

Received	2020-12-23 23:48
Peer-Review Started	2020-12-23 23:49
To Make the First Decision
Return for Revision	2021-02-11 03:27
Revised	2021-02-26 01:10
Second Decision	2021-07-05 05:44
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-07-05 08:34
Articles in Press	2021-07-05 08:34
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-07-10 20:51
Typeset the Manuscript	2021-07-20 06:50
Publish the Manuscript Online	2021-07-26 11:20

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Addition of statins to the standard treatment in patients with cirrhosis: Safety and efficacy
Manuscript Source	Invited Manuscript
All Author List	Alberto E Muñoz, Florencia D Pollarsky, Mónica Marino, Mariano Cartier, Horacio Vázquez, Pablo Salgado and Gustavo Romero
Funding Agency and Grant Number
Corresponding Author	Alberto E Muñoz, MD, Assistant Professor, Associate Specialist, Attending Doctor, Medical Assistant, Staff Physician, Sección Hepatología, Hospital de Gastroenterología Dr. Carlos Bonorino Udaondo, Facultad de Medicina, Universidad de Buenos Aires, Av, Caseros 2061, Ciudad Autónoma de Buenos Aires 1264, Argentina. aemunoz@intramed.net
Key Words	Cirrhosis; Liver disease; Statins; Safety; Efficiency
Core Tip	Several observational studies of statins in patients with liver disease were published, but they were highly biased. On the other hand, only one randomized controlled trial (RCT) improved survival in Child-Pugh class A/B patients but did not reduce variceal rebleeding. Finally, the dose and type of statin to be used should be defined. This review concludes that news RCTs are necessary before endorsing statins use in patients with chronic liver disease.
Publish Date	2021-07-26 11:20
Citation	Muñoz AE, Pollarsky FD, Marino M, Cartier M, Vázquez H, Salgado P, Romero G. Addition of statins to the standard treatment in patients with cirrhosis: Safety and efficacy. World J Gastroenterol 2021; 27(28): 4639-4652
URL	https://www.wjgnet.com/1007-9327/full/v27/i28/4639.htm
DOI	https://dx.doi.org/10.3748/wjg.v27.i28.4639

Full Article (PDF)	WJG-27-4639.pdf
Full Article (Word)	WJG-27-4639.docx
Manuscript File	61954_Review-FilipodiaCL.docx
Answering Reviewers	61954-Answering reviewers.pdf
Audio Core Tip	61954-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	61954-Conflict-of-interest statement.pdf
Copyright License Agreement	61954-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	61954-Language certificate.pdf
Supplementary Material	61954-Supplementary material.pdf
Peer-review Report	61954-Peer-review(s).pdf
Scientific Misconduct Check	61954-Scientific misconduct check.pdf
Scientific Editor Work List	61954-Scientific editor work list.pdf