| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Effectiveness of adjunctive corticosteroid therapy in patients with severe COVID-19: A retrospective cohort study
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Bin Xiong, Li-Min He, Yuan-Yuan Qin, Hu Du, Zhu Zhan, Yi-Hong Zhou, Yao-Kai Chen and An Zhang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Chongqing Special Research Project for Novel Coronavirus Pneumonia Prevention and Control |
cstc2020jscx-fyzxX0012 |
| Emergency Research Project of COVID-19 of Chongqing Health Commission |
2020NCPZX04 |
| Chongqing Special Research Project for Novel Coronavirus Pneumonia Prevention and Control |
cstc2020jscx-fyzx0074 |
|
| Corresponding Author |
An Zhang, MD, PhD, Chief Doctor, Professor, Department of Critical Care Medcine, The Second Affiliated Hospital of Chongqing Medical University, 74 Linjiang Road, Yuzhong District, Chongqing, China, Chongqing 400010, CHINA, China. 300704@hospital.cqmu.edu.cn |
| Key Words |
COVID-19; Corticosteroid; SARS-COV-2; Outcomes |
| Core Tip |
Corticosteroids were used in the treatment of severe acute respiratory syndrome, Middle East respiratory syndrome and coronavirus disease 2019 (COVID-19) in the past. Many studies believe that corticosteroids have an inhibitory effect on inflammatory factors caused by viruses. In this study, 75 patients with severe COVID-19 were studied and divided into either a treatment group or a control group according to corticosteroid use. We found that adjunctive corticosteroid use did not significantly improve clinical outcomes in severe COVID-19 patients, but might promote the absorption of pulmonary lesions. |
| Publish Date |
2021-05-11 11:07 |
| Citation |
Xiong B, He LM, Qin YY, Du H, Zhan Z, Zhou YH, Chen YK, Zhang A. Effectiveness of adjunctive corticosteroid therapy in patients with severe COVID-19: A retrospective cohort study. World J Clin Cases 2021; 9(15): 3546-3558 |
| URL |
https://www.wjgnet.com/2307-8960/full/v9/i15/3546.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v9.i15.3546 |
