Publication Name	World Journal of Orthopedics
Manuscript ID	66228
Country	Spain

Received	2021-03-24 12:41
Peer-Review Started	2021-03-24 12:42
To Make the First Decision
Return for Revision	2021-06-16 14:22
Revised	2021-06-17 15:18
Second Decision	2021-08-18 03:16
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-08-18 06:56
Articles in Press	2021-08-18 06:56
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-08-27 01:05
Typeset the Manuscript	2021-10-12 06:04
Publish the Manuscript Online	2021-10-14 05:19

ISSN	2218-5836 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Orthopedics
Manuscript Type	Case Control Study
Article Title	SARS-CoV-2 outbreak impact on a trauma unit
Manuscript Source	Invited Manuscript
All Author List	Sarah Mills, Aitor Ibarzábal-Gil, José M Martínez-Diez, Javier Pallarés-Sanmartín, Carlos Kalbakdij-Sánchez, Juan C Rubio-Suárez, Itsaso Losantos-García and E Carlos Rodríguez-Merchán
Funding Agency and Grant Number
Corresponding Author	E Carlos Rodríguez-Merchán, MD, PhD, Doctor, Department of Orthopedic Surgery, La Paz University Hospital, Paseo de la Castellana, 261, Madrid 28046, Spain. ecrmerchan@hotmail.com
Key Words	Trauma department; COVID-19 pandemic; SARS-CoV-2 outbreak; Hip fractures; Morbimortality; Polytraumatic patients
Core Tip	Coronavirus severe acute respiratory syndrome-2 (SARS-CoV-2) infection was not a criterion for choosing conservative treatment, unless those patients infected with the virus had a poor general condition that made surgery unadvisable. We did not find a relationship between the employment of anticoagulant therapy and the severity of coronavirus disease 2019 (COVID-19) infection or a different mortality rate. Patients who died during hospitalization due to COVID-19 had higher C-reactive protein levels (P < 0.001) and higher urea levels (P = 0.006). The mortality rate in 2020 was 13.7% during hospitalization; 19% during the first month after discharge and 24.6% in the three months after discharge. The mortality rate in the COVID-19 positive patients subgroup was 38.9% after 6 mo of follow-up. Non-operative treatment in hip fractures was related to SARS-CoV-2 infection (P = 0.03) and with AO 31.B fractures. Polytrauma patients and high energy fractures were more common in 2019 (24%) than in 2020 (11.5%). The main difference between both periods was the injury mechanism.
Publish Date	2021-10-14 05:19
Citation	Mills S, Ibarzábal-Gil A, Martínez-Diez JM, Pallarés-Sanmartín J, Kalbakdij-Sánchez C, Rubio-Suárez JC, Losantos-García I, Rodríguez-Merchán EC. SARS-CoV-2 outbreak impact on a trauma unit. World J Orthop 2021; 12(10): 751-759
URL	https://www.wjgnet.com/2218-5836/full/v12/i10/751.htm
DOI	https://dx.doi.org/10.5312/wjo.v12.i10.751

Full Article (PDF)	WJO-12-751.pdf
Full Article (Word)	WJO-12-751.docx
Manuscript File	66228-Review-Filipodia-CL.docx
Answering Reviewers	66228-Answering reviewers.pdf
Audio Core Tip	66228-Audio core tip.m4a
Biostatistics Review Certificate	66228-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	66228-Conflict-of-interest statement.pdf
Copyright License Agreement	66228-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	66228-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	66228-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	66228-Language certificate.pdf
Peer-review Report	66228-Peer-review(s).pdf
Scientific Misconduct Check	66228-Scientific misconduct check.pdf
Scientific Editor Work List	66228-Scientific editor work list.pdf