| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Linked color imaging vs Lugol chromoendoscopy for esophageal squamous cell cancer and precancerous lesion screening: A noninferiority study
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zi-Xin Wang, Long-Song Li, Song Su, Jin-Ping Li, Bo Zhang, Nan-Jun Wang, Sheng-Zhen Liu, Sha-Sha Wang, Shuai Zhang, Ya-Wei Bi, Fei Gao, Qun Shao, Ning Xu, Bo-Zong Shao, Yi Yao, Fang Liu, En-Qiang Linghu and Ning-Li Chai |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81270564， 82100697 |
|
| Corresponding Author |
Ning-Li Chai, MD, Chief Physician, Professor, Department of Gastroenterology, The First Medical Center of Chinese PLA General Hospital, No. 28 Fuxing Road, Haidian District, Beijing 100853, China. csxlily@163.com |
| Key Words |
Linked color imaging; Lugol chromoendoscopy; Esophageal squamous cell cancer; Precancerous lesions; Color difference |
| Core Tip |
Lugol chromoendoscopy (LCE) has served as the standard screening technique in high-risk patients with esophageal cancer. Nevertheless, LCE can induce esophageal spasms and chest pain and is associated with the risk of aspiration and iodine allergy. Therefore, LCE is not suitable for general population screening. Linked color imaging (LCI) is a novel image-enhanced endoscopy that can distinguish subtle differences in mucosal color. In this study, we compared the use of LCI and LCE in the screening of esophageal neoplastic lesions. Based on our analysis, we found that LCI is more specific than LCE and represents a promising screening strategy. |
| Publish Date |
2023-03-28 12:59 |
| Citation |
Wang ZX, Li LS, Su S, Li JP, Zhang B, Wang NJ, Liu SZ, Wang SS, Zhang S, Bi YW, Gao F, Shao Q, Xu N, Shao BZ, Yao Y, Liu F, Linghu EQ, Chai NL. Linked color imaging vs Lugol chromoendoscopy for esophageal squamous cell cancer and precancerous lesion screening: A noninferiority study. World J Gastroenterol 2023; 29(12): 1899-1910 |
| URL |
https://www.wjgnet.com/1007-9327/full/v29/i12/1899.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v29.i12.1899 |
