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12/30/2024 10:05:02 AM | Browse: 76 | Download: 122
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Received |
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2024-08-21 06:30 |
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Peer-Review Started |
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2024-08-10 15:16 |
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To Make the First Decision |
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Return for Revision |
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2024-11-10 03:05 |
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Revised |
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2024-11-21 10:27 |
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Second Decision |
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2024-12-16 02:46 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-12-16 05:59 |
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Articles in Press |
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2024-12-16 05:59 |
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Publication Fee Transferred |
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2024-11-28 08:20 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-12-20 07:05 |
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Publish the Manuscript Online |
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2024-12-30 09:50 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Effect of Modulen vs budesonide on clinical response and mucosal healing in Crohn’s patients
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Baruch Ovadia, Eva Niv, Sara Stern Katie, Elisabeth Mahajna, Oren Gal and Yael Kopelman |
| Funding Agency and Grant Number |
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| Corresponding Author |
Eva Niv, MD, Department of Gastroenterology, Meuhedet Health services, Kibutz Galuet 9 Hadera, Hadera 38100, Haifa, Israel. niveva022@gmail.com |
| Key Words |
Crohn’s disease; Modulen oral polymeric diet; Transforming growth factor-beta 2; Budesonide; Mucosal healing; Clinical response; Capsule endoscopy; Small bowel capsule |
| Core Tip |
The effects of modulen and budesonide on mucosal healing in Crohn’s disease remain underexplored. In this study, the small bowel capsule endoscopy was used for the first time to compare the mucosal effect of modulen and budesonide on patients with newly diagnosed mild-moderate Crohn’s disease. The study results demonstrate that modulen shows significant clinical and mucosal improvements, while budesonide primarily improves laboratory parameters. The complementary effect of both of them should be explored to maximize the benefit to the patients. |
| Publish Date |
2024-12-30 09:50 |
| Citation |
<p>Ovadia B, Niv E, Stern Katie S, Mahajna E, Gal O, Kopelman Y. Effect of Modulen vs budesonide on clinical response and mucosal healing in Crohn’s patients. <i>World J Gastroenterol</i> 2025; 31(5): 100238</p> |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i5/100238.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i5.100238 |
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