Publication Name	World Journal of Clinical Pediatrics
Manuscript ID	100453
Country	India

Received	2024-08-22 06:53
Peer-Review Started	2024-08-16 18:30
To Make the First Decision
Return for Revision	2024-09-19 21:23
Revised	2024-10-02 20:42
Second Decision	2024-10-30 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-10-30 13:54
Articles in Press	2024-10-30 13:54
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-11-06 01:35
Publish the Manuscript Online	2024-12-20 07:07

ISSN	2219-2808 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Pediatrics
Manuscript Type	Prospective Study
Article Title	Cardiovascular involvement in multisystem inflammatory syndrome in children and midterm follow-up from a pediatric tertiary center in India
Manuscript Source	Invited Manuscript
All Author List	Poovazhagi Varadarajan, Ritchie Sharon Solomon, Seenivasan Subramani, Ramesh Subramanian, Gomathy Srividya and Elilarasi Raghunathan
Funding Agency and Grant Number
Corresponding Author	Ritchie Sharon Solomon, MD, Assistant Professor, Department of Pediatric Cardiology, Institute of Child Health and Hospital for Children, Madras Medical College, Periyar Salai, Park Town, Chennai 600003, Tamil Nādu, India. ritchie_sharon@yahoo.com
Key Words	Multisystem inflammatory syndrome in children; Cardiovascular; Midterm follow-up; Coronary artery aneurysm; Shock; Left ventricular dysfunction
Core Tip	Multisystem inflammatory syndrome in children associated with severe acute respiratory syndrome coronavirus can affect the cardiovascular system leading to morbidity and mortality. This prospective study analysed the spectrum of cardiovascular involvement and aimed at determining the associations with clinical and laboratory parameters. Of the 211 patients with cardiac involvement, shock was the predominant finding followed by pericardial effusion, left ventricular (LV) dysfunction, mitral regurgitation and coronary aneurysm. LV function normalized in majority of children within two weeks. Most of the coronary abnormalities normalized within 6 months. None of the laboratory parameter was predictive of cardiac involvement.
Publish Date	2024-12-20 07:07
Citation	<p>Varadarajan P, Solomon RS, Subramani S, Subramanian R, Srividya G, Raghunathan E. Cardiovascular involvement in multisystem inflammatory syndrome in children and midterm follow-up from a pediatric tertiary center in India. <i>World J Clin Pediatr</i> 2025; 14(1): 100453</p>
URL	https://www.wjgnet.com/2219-2808/full/v14/i1/100453.htm
DOI	https://dx.doi.org/10.5409/wjcp.v14.i1.100453

Full Article (PDF)	WJCP-14-100453-with-cover.pdf
CONSORT 2010 Statement	100453-CONSORT-2010-statement.pdf
Manuscript File	100453_Auto_Edited_035029.docx
Answering Reviewers	100453-answering-reviewers.pdf
Audio Core Tip	100453-audio.mp3
Biostatistics Review Certificate	100453-biostatistics-statement.pdf
Clinical Trial Registration Statement	100453-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form	100453-conflict-of-interest-statement.pdf
Copyright License Agreement	100453-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s)	100453-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	100453-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	100453-non-native-speakers.pdf
Peer-review Report	100453-peer-reviews.pdf
Scientific Misconduct Check	100453-scientific-misconduct-check.png
Scientific Editor Work List	100453-scientific-editor-work-list.pdf
CrossCheck Report	100453-crosscheck-report.pdf