Publication Name	World Journal of Gastroenterology
Manuscript ID	100855
Country	China

Received	2024-08-30 06:01
Peer-Review Started	2024-09-05 04:00
To Make the First Decision
Return for Revision	2024-12-29 01:57
Revised	2025-01-10 13:47
Second Decision	2025-02-18 02:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-02-18 06:23
Articles in Press	2025-02-18 06:23
Publication Fee Transferred	2025-01-16 05:31
Edit the Manuscript by Language Editor	2025-02-24 20:10
Typeset the Manuscript	2025-03-06 13:45
Publish the Manuscript Online	2025-03-26 08:40

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Cohort Study
Article Title	Characterization of gallbladder stones associated with occult pancreaticobiliary reflux using computed tomography
Manuscript Source	Unsolicited Manuscript
All Author List	Chen Qiu, Yu-Kai Xiang, Hai Hu, Xuan-Bo Da, Gang Li, Yue-Yi Zhang, Hong-Lei Zhang, Cheng Zhang and Yu-Long Yang
Funding Agency and Grant Number	Funding Agency Grant Number Key Specialty Construction Project of Shanghai Pudong New Area Health Commission PWZzk2022-17 Shanghai East Hospital Clinical Research Project DFLC2022019 the Featured Clinical Discipline Project of Shanghai Pudong District PWYts2021-06
Corresponding Author	Yu-Long Yang, Center of Gallbladder Disease, Shanghai East Hospital, Institute of Gallstone Disease, Tongji University School of Medicine, No. 150 Jimo Road, Shanghai 200120, China. yyl516@tongji.edu.cn
Key Words	Occult pancreaticobiliary reflux; Pancreaticobiliary maljunction; Pancreaticobiliary reflux; Computed tomography; Diagnostic model
Core Tip	This study presents a novel approach to diagnosing occult pancreaticobiliary reflux (OPBR) in patients with gallbladder stones using non-invasive computed tomography (CT) imaging. The findings highlight that uniform and CT-invisible stones, along with lower stone density, are significant predictors of OPBR. The development of a predictive nomogram based on these imaging features offers clinicians an effective tool for early identification and intervention, potentially reducing the risk of recurrent biliary pathologies post-cholecystectomy. This innovative diagnostic model may enhance patient management and improve clinical outcomes in gallbladder disease.
Publish Date	2025-03-26 08:40
Citation	<p>Qiu C, Xiang YK, Hu H, Da XB, Li G, Zhang YY, Zhang HL, Zhang C, Yang YL. Characterization of gallbladder stones associated with occult pancreaticobiliary reflux using computed tomography. <i>World J Gastroenterol</i> 2025; 31(12): 100855</p>
URL	https://www.wjgnet.com/1007-9327/full/v31/i12/100855.htm
DOI	https://dx.doi.org/10.3748/wjg.v31.i12.100855

Full Article (PDF)	WJG-31-100855-with-cover.pdf
STROBE Statement	100855-STROBE-statement.pdf
Manuscript File	100855_Auto_Edited_090348.docx
Answering Reviewers	100855-answering-reviewers.pdf
Audio Core Tip	100855-audio.mp3
Biostatistics Review Certificate	100855-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	100855-conflict-of-interest-statement.pdf
Copyright License Agreement	100855-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	100855-foundation-statement.pdf
Signed Informed Consent Form(s) or Document(s)	100855-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	100855-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	100855-non-native-speakers.pdf
Peer-review Report	100855-peer-reviews.pdf
Scientific Misconduct Check	100855-scientific-misconduct-check.png
Scientific Editor Work List	100855-scientific-editor-work-list.pdf
CrossCheck Report	100855-crosscheck-report.pdf