Publication Name	World Journal of Stem Cells
Manuscript ID	101030
Country	China

Received	2024-09-02 12:19
Peer-Review Started	2024-09-02 12:19
To Make the First Decision
Return for Revision	2024-11-27 10:26
Revised	2024-12-09 17:11
Second Decision	2025-01-22 02:28
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-02-07 03:55
Articles in Press	2025-02-07 03:55
Publication Fee Transferred	2024-12-12 10:23
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-02-17 01:37
Publish the Manuscript Online	2025-02-24 05:39

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Biochemistry & Molecular Biology
Manuscript Type	Basic Study
Article Title	Fetal mice dermal mesenchymal stem cells promote wound healing by inducing M2 type macrophage polarization
Manuscript Source	Unsolicited Manuscript
All Author List	Zhen-Yu Xia, Yi Wang, Nian Shi, Mei-Qi Lu, Yun-Xiang Deng, Yong-Jun Qi, Xing-Lei Wang, Jie Zhao and Du-Yin Jiang
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81873934 Jinan Science and Technology Planning Project 202225065
Corresponding Author	Du-Yin Jiang, MD, Emergency Medicine Center, The Second Hospital of Shandong University, No. 247 Beiyuan Street, Jinan 250033, Shandong Province, China. jduyin0227@163.com
Key Words	Fetal dermal mesenchymal stem cells; Macrophage polarization; Wound healing; Immunomodulation; M2 phenotype
Core Tip	This study investigates the role of fetal dermal mesenchymal stem cells in wound healing by modulating macrophage polarization towards a pro-healing M2 phenotype. Using flow cytometry, reverse transcriptase polymerase chain reaction, and histology, we demonstrate that fetal dermal mesenchymal stem cells promote a reparative immune environment, accelerating wound closure, enhancing collagen deposition, and supporting vascular regeneration in a mouse model.
Publish Date	2025-02-24 05:39
Citation	<p>Xia ZY, Wang Y, Shi N, Lu MQ, Deng YX, Qi YJ, Wang XL, Zhao J, Jiang DY. Fetal mice dermal mesenchymal stem cells promote wound healing by inducing M2 type macrophage polarization. <i>World J Stem Cells</i> 2025; 17(2): 101030</p>
URL	https://www.wjgnet.com/1948-0210/full/v17/i2/101030.htm
DOI	https://dx.doi.org/10.4252/wjsc.v17.i2.101030

Full Article (PDF)	WJSC-17-101030-with-cover.pdf
The ARRIVE Guidelines	101030-The-ARRIVE-Guidelines.pdf
Manuscript File	101030_Auto_Edited_055619.docx
Answering Reviewers	101030-answering-reviewers.pdf
Audio Core Tip	101030-audio.mp3
Biostatistics Review Certificate	101030-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	101030-conflict-of-interest-statement.pdf
Copyright License Agreement	101030-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	101030-foundation-statement.pdf
Institutional Animal Care and Use Committee Approval Form or Document	101030-institutional-animal-care-and-use-committee-statement.pdf
Non-Native Speakers of English Editing Certificate	101030-non-native-speakers.pdf
Peer-review Report	101030-peer-reviews.pdf
Scientific Misconduct Check	101030-scientific-misconduct-check.png
Scientific Editor Work List	101030-scientific-editor-work-list.pdf
CrossCheck Report	101030-crosscheck-report.pdf