Publication Name	World Journal of Stem Cells
Manuscript ID	101347
Country	Italy

Received	2024-09-11 12:31
Peer-Review Started	2024-09-11 12:31
To Make the First Decision
Return for Revision	2024-09-24 09:09
Revised	2024-09-30 10:11
Second Decision	2024-11-25 02:34
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-11-26 01:11
Articles in Press	2024-11-26 01:11
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-12-09 21:54
Typeset the Manuscript	2024-12-12 09:40
Publish the Manuscript Online	2025-01-20 02:39

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Dentistry, Oral Surgery & Medicine
Manuscript Type	Letter to the Editor
Article Title	Melatonin regulation and the function of periodontal ligament: Future perspective and challenges
Manuscript Source	Invited Manuscript
All Author List	Andrea Scribante
Funding Agency and Grant Number
Corresponding Author	Andrea Scribante, PhD, Professor, Section of Dentistry, Department of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, Piazzale Golgi 2, Pavia 27100, Italy. andrea.scribante@unipv.it
Key Words	Cellular ageing; Dentistry; Melatonin; Oxidative stress; Periodontal ligament; Periodontal regeneration; Periodontology; Cellular ageing
Core Tip	The text highlights recent developments in periodontal research, showing that melatonin delays the ageing of periodontal ligament stem cells and enhances their regenerative capacity, in particular by acting on the Hippo-Yes-associated protein signalling pathway. This could be a breakthrough in the treatment of age-related periodontal disease.
Publish Date	2025-01-20 02:39
Citation	<p>Scribante A. Melatonin regulation and the function of periodontal ligament: Future perspective and challenges. <i>World J Stem Cells</i> 2025; 17(1): 101347</p>
URL	https://www.wjgnet.com/1948-0210/full/v17/i1/101347.htm
DOI	https://dx.doi.org/10.4252/wjsc.v17.i1.101347

Full Article (PDF)	WJSC-17-101347-with-cover.pdf
Manuscript File	101347_Auto_Edited_085849.docx
Answering Reviewers	101347-answering-reviewers.pdf
Audio Core Tip	101347-audio.wma
Conflict-of-Interest Disclosure Form	101347-conflict-of-interest-statement.pdf
Copyright License Agreement	101347-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	101347-non-native-speakers.pdf
Peer-review Report	101347-peer-reviews.pdf
Scientific Misconduct Check	101347-scientific-misconduct-check.png
Scientific Editor Work List	101347-scientific-editor-work-list.pdf
CrossCheck Report	101347-crosscheck-report.pdf