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4/25/2025 8:04:13 AM | Browse: 27 | Download: 33
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Received |
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2024-09-18 06:04 |
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Peer-Review Started |
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2024-10-01 05:33 |
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To Make the First Decision |
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Return for Revision |
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2024-12-12 09:16 |
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Revised |
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2025-01-17 12:31 |
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Second Decision |
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2025-02-10 10:03 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-02-20 09:06 |
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Articles in Press |
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2025-02-20 09:06 |
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Publication Fee Transferred |
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2025-01-20 11:19 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-03-07 13:11 |
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Publish the Manuscript Online |
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2025-04-25 07:53 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Minireviews |
| Article Title |
Therapeutic potential of integrins in diabetic retinopathy
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Li-Mei He, Sarul Borjigin, Xin-Qi Chen, Zhao-Li Yan and Ming-Jie Wang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of Inner Mongolia |
2022MS08057 |
| 2022 Autonomous Region Medical and Health Science and Technology Plan Projects |
202202190 |
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| Corresponding Author |
Zhao-Li Yan, Chief Physician, MD, Department of Endocrinology, The Affiliated Hospital of Inner Mongolia Medical University, No. 1 Tongdao North Road, Hohhot 010000, Inner Mongolia Autonomous Region, China. aliceyzl@126.com |
| Key Words |
Diabetic retinopathy; Integrin; Inflammation; Microvascular permeability; Microthrombus formation; Angiogenesis; Integrin inhibitor |
| Core Tip |
Diabetic retinopathy (DR) is a serious and common complication of diabetes mellitus. Prolonged high glucose levels damage microvessels in the retina and can lead to blindness. Current treatment options are limited, warranting novel therapeutic strategies. Therapies targeting integrins have shown promise. This review outlines the current understanding of the role of integrins in DR and the findings of preclinical studies and clinical trials investigating the potential of various integrin-targeted therapies. Thus, this review paper captures the current state of the field and identifies possible avenues for further study and treatment approaches. |
| Publish Date |
2025-04-25 07:53 |
| Citation |
<p>He LM, Borjigin S, Chen XQ, Yan ZL, Wang MJ. Therapeutic potential of integrins in diabetic retinopathy. <i>World J Diabetes</i> 2025; 16(5): 101509</p> |
| URL |
https://www.wjgnet.com/1948-9358/full/v16/i5/101509.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v16.i5.101509 |
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