Publication Name	World Journal of Gastroenterology
Manuscript ID	101594
Country	South Korea

Received	2024-09-20 04:38
Peer-Review Started	2024-09-20 04:38
To Make the First Decision
Return for Revision	2024-10-15 03:24
Revised	2024-10-22 00:50
Second Decision	2024-10-30 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-10-30 14:16
Articles in Press	2024-10-30 14:16
Publication Fee Transferred	2024-11-04 01:06
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-11-12 06:17
Publish the Manuscript Online	2024-11-21 07:04

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Establishment of a chronic biliary disease mouse model with cholecystoduodenal anastomosis for intestinal microbiome preservation
Manuscript Source	Unsolicited Manuscript
All Author List	Yunseon Jang, Jung Yeon Kim, Song Yeon Han, Arum Park, So Jeong Baek, Gyurim Lee, Jihee Kang, Hyewon Ryu and Seok-Hwan Kim
Funding Agency and Grant Number	Funding Agency Grant Number Korea Health Technology R&D Project through the Korea Health Industry Development Institute, Funded by the Ministry of Health & Welfare, Republic of Korea HI22C12HR20C0025 and HI22C1212 the National Research Foundation of Korea Grant Funded by the Korea Government RS-2023-00238188
Corresponding Author	Seok-Hwan Kim, MD, PhD, Assistant Professor, Department of Surgery, Chungnam National University Hospital, 282 Munhwa-ro, Jung-gu, Daejeon 35015, South Korea. kjxh7@cnuh.co.kr
Key Words	Experimental animal model; Cholecystoduodenal fistula; Anastomosis; Biliary Disease; Microbiome
Core Tip	This study introduces a novel cholecystoduodenal anastomosis mouse model to replicate the ascending infection and inflammation observed in human biliary diseases without the use of antibiotics. The model demonstrates localized biliary inflammation and microbial dysbiosis, particularly involving Escherichia coli and Enterococcus, closely mimicking human conditions. This model offers a valuable platform for investigating microbiome-based therapies aimed at preventing and treating chronic biliary diseases.
Publish Date	2024-11-21 07:04
Citation	<p>Jang Y, Kim JY, Han SY, Park A, Baek SJ, Lee G, Kang J, Ryu H, Kim SH. Establishment of a chronic biliary disease mouse model with cholecystoduodenal anastomosis for intestinal microbiome preservation. <i>World J Gastroenterol</i> 2024; 30(46): 4937-4946</p>
URL	https://www.wjgnet.com/1007-9327/full/v30/i46/4937.htm
DOI	https://dx.doi.org/10.3748/wjg.v30.i46.4937

Full Article (PDF)	WJG-30-4937-with-cover.pdf
The ARRIVE Guidelines	101594-The-ARRIVE-Guidelines.pdf
Manuscript File	101594_Auto_Edited_012405.docx
Answering Reviewers	101594-answering-reviewers.pdf
Audio Core Tip	101594-audio.mp3
Biostatistics Review Certificate	101594-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	101594-conflict-of-interest-statement.pdf
Copyright License Agreement	101594-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	101594-foundation-statement.pdf
Institutional Animal Care and Use Committee Approval Form or Document	101594-institutional-animal-care-and-use-committee-statement.pdf
Institutional Review Board Approval Form or Document	101594-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	101594-non-native-speakers.pdf
Supplementary Material	101594-supplementary-material.pdf
Peer-review Report	101594-peer-reviews.pdf
Scientific Misconduct Check	101594-scientific-misconduct-check.png
Scientific Editor Work List	101594-scientific-editor-work-list.pdf
CrossCheck Report	101594-crosscheck-report.pdf