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3/3/2025 8:29:46 AM | Browse: 77 | Download: 83
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Received |
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2024-09-26 07:26 |
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Peer-Review Started |
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2024-09-26 07:26 |
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To Make the First Decision |
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Return for Revision |
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2024-11-25 07:05 |
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Revised |
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2024-12-05 05:23 |
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Second Decision |
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2025-01-02 02:42 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-01-02 10:57 |
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Articles in Press |
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2025-01-02 10:57 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-02-27 03:22 |
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Publish the Manuscript Online |
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2025-03-03 07:31 |
ISSN |
2150-5349 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Minireviews |
Article Title |
Rebamipide in gastric mucosal protection and healing: An Asian perspective
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Manish Kak |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Dr Reddy's Laboratories, Hyderabad, India |
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Corresponding Author |
Manish Kak, MD, Department of Gastroenterology, Manipal Hospital, NH-24 Hapur Road, Near Landcraft Golflinks, Pandav Nagar, Ghaziabad 201002, Uttar Pradesh, India. manishkak@yahoo.com |
Key Words |
Rebamipide; Peptic ulcer; Gastroesophageal reflux disease; Mucosal protection; Treatment |
Core Tip |
This review highlights rebamipide’s superior safety and efficacy in treating gastric ulcers and mucosal disorders, making it a strong candidate for inclusion in global treatment guidelines. An extensive literature review reveals its multifaceted mechanism of action, including prostaglandin synthesis, free radical scavenging, and mucin production enhancement, leading to enhanced mucosal protection and ulcer healing. Rebamipide often surpasses other common treatments like pantoprazole and esomeprazole due to its low adverse event rate and mild side effects. Its broad application extends to ophthalmology, oncology, and bone regeneration, further underscoring its therapeutic versatility. |
Publish Date |
2025-03-03 07:31 |
Citation |
<p>Kak M. Rebamipide in gastric mucosal protection and healing: An Asian perspective. <i>World J Gastrointest Pharmacol Ther</i> 2025; 16(1): 101753</p> |
URL |
https://www.wjgnet.com/2150-5349/full/v16/i1/101753.htm |
DOI |
https://dx.doi.org/10.4292/wjgpt.v16.i1.101753 |
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