Publication Name	World Journal of Clinical Oncology
Manuscript ID	102223
Country	China

Received	2024-10-12 06:19
Peer-Review Started	2024-10-12 06:19
To Make the First Decision
Return for Revision	2025-01-03 09:48
Revised	2025-02-10 14:34
Second Decision	2025-02-19 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-02-19 07:35
Articles in Press	2025-02-19 07:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-03-10 00:54
Publish the Manuscript Online	2025-05-20 03:37

ISSN	2218-4333 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Editorial
Article Title	East meets West: The winning combination against BRAF V600E metastatic colorectal cancer
Manuscript Source	Invited Manuscript
All Author List	Wen-Ming Liu and Xiao-Bing Li
Funding Agency and Grant Number	Funding Agency Grant Number Natural Science Foundation of Hubei Province No. 2019CFC929
Corresponding Author	Xiao-Bing Li, Assistant Professor, MD, PhD, Department of Thoracic Oncology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 116 South Zhuodaoquan Road, Hongshan District, Wuhan 430079, Hubei Province, China. lixiaobing0629@126.com
Key Words	Traditional Chinese medicine; Western medicine; BRAF mutation; Metastatic colorectal cancer; Medicine
Core Tip	Bian et al’s study demonstrates that integrated treatment with tolerated toxicity significantly improves survival in patients with BRAF mutant advanced colorectal cancer compared to traditional Western medicine alone, especially for certain subgroups. However, while this study provides new evidence supporting combined therapies, it also has limitations, such as unclear mechanisms of action, lack of detailed treatment protocols, and a small sample size. Summarizing these new findings and addressing the study’s issues will not only aid in the clinical application of integrated treatments for colorectal cancer but also promote the development of personalized therapies for this disease.
Publish Date	2025-05-20 03:37
Citation	<p>Liu WM, Li XB. East meets West: The winning combination against BRAF V600E metastatic colorectal cancer. <i>World J Clin Oncol</i> 2025; 16(5): 102223</p>
URL	https://www.wjgnet.com/2218-4333/full/v16/i5/102223.htm
DOI	https://dx.doi.org/10.5306/wjco.v16.i5.102223

Full Article (PDF)	WJCO-16-102223-with-cover.pdf
Manuscript File	102223_Auto_Edited_033350.docx
Answering Reviewers	102223-answering-reviewers.pdf
Audio Core Tip	102223-audio.m4a
Conflict-of-Interest Disclosure Form	102223-conflict-of-interest-statement.pdf
Copyright License Agreement	102223-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	102223-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	102223-non-native-speakers.pdf
Peer-review Report	102223-peer-reviews.pdf
Scientific Misconduct Check	102223-scientific-misconduct-check.png
Scientific Editor Work List	102223-scientific-editor-work-list.pdf
CrossCheck Report	102223-crosscheck-report.pdf