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2/28/2025 11:47:27 AM | Browse: 107 | Download: 91
Publication Name World Journal of Diabetes
Manuscript ID 102554
Country China
Received
2024-10-22 02:23
Peer-Review Started
2024-10-31 11:50
To Make the First Decision
Return for Revision
2025-01-12 06:36
Revised
2025-01-14 11:36
Second Decision
2025-02-05 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-02-05 04:02
Articles in Press
2025-02-05 04:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
2025-02-10 02:05
Typeset the Manuscript
2025-02-21 05:12
Publish the Manuscript Online
2025-02-28 10:47
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research & Experimental
Manuscript Type Editorial
Article Title Dysfunctional glucose metabolism triggers oxidative stress to induce kidney injury in diabetes
Manuscript Source Invited Manuscript
All Author List Meng Gao, Meng-Ting Dai and Guo-Hua Gong
Funding Agency and Grant Number
Funding Agency Grant Number
The Basic Research Project of Wenzhou Municipal Science and Technology Bureau No. Y20240008
The Medical Health Science and Technology Project of Zhejiang Provincial Health Commission No. 2024KY138
The Key Laboratory of School of Laboratory Medicine and Life Sciences, Wenzhou Medical University of China No. JS2023003
Corresponding Author Guo-Hua Gong, PhD, Professor, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Chashan Higher Education Park, Wenzhou 325035, Zhejiang Province, China. guohgong@wmu.edu.cn
Key Words Glucose metabolism; Sodium-D-glucose cotransporter 1; Glucose reabsorption; Mitochondrial dysfunction; Reactive oxygen species; Inflammation
Core Tip In diabetes, insulin resistance and insufficient insulin release lead to a decrease in glucose uptake by muscles and fat tissues, resulting in elevated blood glucose levels, which are dangerous to human organs. The tolerance of high glucose switches the metabolism of glucose, which causes mitochondrial dysfunction. Oxidative stress induced by excess reactive oxygen species generated by dysfunctional mitochondria causes cell damage and thus stimulates proinflammatory factor production and tissue injury. Therefore, antidiabetic therapies are aimed at decreasing blood glucose and oxidative stress.
Publish Date 2025-02-28 10:47
Citation <p>Gao M, Dai MT, Gong GH. Dysfunctional glucose metabolism triggers oxidative stress to induce kidney injury in diabetes. <i>World J Diabetes</i> 2025; 16(4): 102554</p>
URL https://www.wjgnet.com/1948-9358/full/v16/i4/102554.htm
DOI https://dx.doi.org/10.4239/wjd.v16.i4.102554
Full Article (PDF) WJD-16-102554-with-cover.pdf
Manuscript File 102554_Auto_Edited_032116.docx
Answering Reviewers 102554-answering-reviewers.pdf
Audio Core Tip 102554-audio.wav
Conflict-of-Interest Disclosure Form 102554-conflict-of-interest-statement.pdf
Copyright License Agreement 102554-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 102554-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate 102554-non-native-speakers.pdf
Peer-review Report 102554-peer-reviews.pdf
Scientific Misconduct Check 102554-scientific-misconduct-check.png
Scientific Editor Work List 102554-scientific-editor-work-list.pdf
CrossCheck Report 102554-crosscheck-report.pdf