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4/30/2025 9:29:21 AM | Browse: 5 | Download: 1
Publication Name World Journal of Psychiatry
Manuscript ID 103701
Country China
Received
2024-11-29 07:57
Peer-Review Started
2024-11-29 07:58
To Make the First Decision
Return for Revision
2025-01-10 09:27
Revised
2025-01-24 09:27
Second Decision
2025-03-17 02:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-03-17 07:41
Articles in Press
2025-03-17 07:41
Publication Fee Transferred
2025-02-14 15:24
Edit the Manuscript by Language Editor
2025-03-24 02:19
Typeset the Manuscript
2025-04-15 07:19
Publish the Manuscript Online
2025-04-30 08:58
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychiatry
Manuscript Type Prospective Study
Article Title Effectiveness and safety of blonanserin monotherapy in first-episode schizophrenia with and without prominent negative symptoms: A prospective study
Manuscript Source Unsolicited Manuscript
All Author List Li-He Chen, Qian Guo, Yao Hu, Xiao-Hua Liu, Hao Hu, Hai-Ying Chen, Cai-Ping Liu, Hua-Fang Li, Jin-Dong Chen and Guan-Jun Li
Funding Agency and Grant Number
Corresponding Author Guan-Jun Li, Chief Physician, PhD, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, No. 600 Wanping Nan Road, Shanghai 200030, China. liguanjun66@126.com
Key Words Schizophrenia; Blonanserin; Negative symptoms; Effectiveness; Safety; Dose
Core Tip Blonanserin effectively improved overall and negative symptoms of first-episode schizophrenia with an acceptable safety profile. High-dose blonanserin showed greater efficacy than low-dose for patients with prominent negative symptoms without an increase in adverse drug reactions. Conversely, low-dose blonanserin provided comparable clinical improvement and safety compared to high-dose for patients without prominent negative symptoms.
Publish Date 2025-04-30 08:58
Citation <p>Chen LH, Guo Q, Hu Y, Liu XH, Hu H, Chen HY, Liu CP, Li HF, Chen JD, Li GJ. Effectiveness and safety of blonanserin monotherapy in first-episode schizophrenia with and without prominent negative symptoms: A prospective study. <i>World J Psychiatry</i> 2025; 15(5): 103701</p>
URL https://www.wjgnet.com/2220-3206/full/v15/i5/103701.htm
DOI https://dx.doi.org/10.5498/wjp.v15.i5.103701
Full Article (PDF) WJP-15-103701-with-cover.pdf
CONSORT 2010 Statement 103701-CONSORT-2010-statement.pdf
Manuscript File 103701_Auto_Edited_083723.docx
Answering Reviewers 103701-answering-reviewers.pdf
Audio Core Tip 103701-audio.m4a
Biostatistics Review Certificate 103701-biostatistics-statement.pdf
Clinical Trial Registration Statement 103701-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form 103701-conflict-of-interest-statement.pdf
Copyright License Agreement 103701-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 103701-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 103701-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 103701-non-native-speakers.pdf
Peer-review Report 103701-peer-reviews.pdf
Scientific Misconduct Check 103701-scientific-misconduct-check.png
Scientific Editor Work List 103701-scientific-editor-work-list.pdf
CrossCheck Report 103701-crosscheck-report.pdf