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4/30/2025 9:29:21 AM | Browse: 5 | Download: 1
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Received |
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2024-11-29 07:57 |
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Peer-Review Started |
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2024-11-29 07:58 |
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To Make the First Decision |
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Return for Revision |
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2025-01-10 09:27 |
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Revised |
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2025-01-24 09:27 |
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Second Decision |
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2025-03-17 02:36 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-03-17 07:41 |
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Articles in Press |
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2025-03-17 07:41 |
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Publication Fee Transferred |
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2025-02-14 15:24 |
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Edit the Manuscript by Language Editor |
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2025-03-24 02:19 |
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Typeset the Manuscript |
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2025-04-15 07:19 |
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Publish the Manuscript Online |
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2025-04-30 08:58 |
ISSN |
2220-3206 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Psychiatry |
Manuscript Type |
Prospective Study |
Article Title |
Effectiveness and safety of blonanserin monotherapy in first-episode schizophrenia with and without prominent negative symptoms: A prospective study
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Li-He Chen, Qian Guo, Yao Hu, Xiao-Hua Liu, Hao Hu, Hai-Ying Chen, Cai-Ping Liu, Hua-Fang Li, Jin-Dong Chen and Guan-Jun Li |
Funding Agency and Grant Number |
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Corresponding Author |
Guan-Jun Li, Chief Physician, PhD, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, No. 600 Wanping Nan Road, Shanghai 200030, China. liguanjun66@126.com |
Key Words |
Schizophrenia; Blonanserin; Negative symptoms; Effectiveness; Safety; Dose |
Core Tip |
Blonanserin effectively improved overall and negative symptoms of first-episode schizophrenia with an acceptable safety profile. High-dose blonanserin showed greater efficacy than low-dose for patients with prominent negative symptoms without an increase in adverse drug reactions. Conversely, low-dose blonanserin provided comparable clinical improvement and safety compared to high-dose for patients without prominent negative symptoms. |
Publish Date |
2025-04-30 08:58 |
Citation |
<p>Chen LH, Guo Q, Hu Y, Liu XH, Hu H, Chen HY, Liu CP, Li HF, Chen JD, Li GJ. Effectiveness and safety of blonanserin monotherapy in first-episode schizophrenia with and without prominent negative symptoms: A prospective study. <i>World J Psychiatry</i> 2025; 15(5): 103701</p> |
URL |
https://www.wjgnet.com/2220-3206/full/v15/i5/103701.htm |
DOI |
https://dx.doi.org/10.5498/wjp.v15.i5.103701 |
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