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4/30/2025 9:29:21 AM | Browse: 4 | Download: 0
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Received |
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2024-11-29 09:28 |
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Peer-Review Started |
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2024-11-29 09:28 |
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To Make the First Decision |
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Return for Revision |
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2025-02-10 08:31 |
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Revised |
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2025-02-23 16:42 |
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Second Decision |
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2025-03-26 03:20 |
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Accepted by Journal Editor-in-Chief |
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2025-03-29 10:09 |
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Accepted by Executive Editor-in-Chief |
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2025-03-31 06:26 |
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Articles in Press |
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2025-03-31 06:26 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2025-04-06 20:01 |
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Typeset the Manuscript |
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2025-04-21 01:27 |
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Publish the Manuscript Online |
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2025-04-30 08:58 |
ISSN |
2220-3206 (online) |
Open Access |
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Psychiatry |
Manuscript Type |
Review |
Article Title |
Gut-brain connection in schizophrenia: A narrative review
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Asma Iqbal, Syed Faqeer Hussain Bokhari, Muneeb Ur Rehman, Syed Muhammad Faizan Sattar, Danyal Bakht, Wahidullah Dost and Abdul Basit |
Funding Agency and Grant Number |
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Corresponding Author |
Wahidullah Dost, Department of Curative Medicine, Kabul University of Medical Sciences, Karte-e-sakhi, Kabul 10001, Afghanistan. wahidullahdost96@gmail.com |
Key Words |
Schizophrenia; Gut-brain axis; Microbiota; Neuroinflammation; Probiotics |
Core Tip |
Emerging research highlights the critical role of the gut-brain axis in schizophrenia. Dysbiosis, or imbalances in gut microbiota, may contribute to neuroinflammation, neurotransmitter dysregulation, and blood-brain barrier disruption, all of which are central to the disorder’s pathophysiology. Targeting gut health through probiotics, prebiotics, dietary changes, and fecal microbiota transplantation holds promise as adjunctive therapies to traditional antipsychotics, offering new, integrative strategies for improving cognitive, emotional, and behavioral outcomes in schizophrenia. Further research is needed to validate and refine these approaches. |
Publish Date |
2025-04-30 08:58 |
Citation |
<p>Iqbal A, Bokhari SFH, Rehman MU, Faizan Sattar SM, Bakht D, Dost W, Basit A. Gut-brain connection in schizophrenia: A narrative review. <i>World J Psychiatry</i> 2025; 15(5): 103751</p> |
URL |
https://www.wjgnet.com/2220-3206/full/v15/i5/103751.htm |
DOI |
https://dx.doi.org/10.5498/wjp.v15.i5.103751 |
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