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Publication Name World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID 103898
Country India
Received
2024-12-13 10:51
Peer-Review Started
2024-12-13 10:51
To Make the First Decision
Return for Revision
2025-01-16 13:30
Revised
2025-01-24 11:27
Second Decision
2025-02-10 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-02-10 08:49
Articles in Press
2025-02-10 08:49
Publication Fee Transferred
2025-01-28 10:06
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-02-13 03:15
Publish the Manuscript Online
2025-03-03 07:31
ISSN 2150-5349 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Real-world-evidence, prospective-observational study to evaluate safety and effectiveness of rabeprazole dual-delayed-release capsules in patients with gastroesophageal reflux disease
Manuscript Source Unsolicited Manuscript
All Author List Parimal Lawate, Virender Chauhan, L Rajendra Prasad, Abhimanrao Pawar, Atul G Puranik, Alok Bansal, Abhiram Koganti, Ashok Jaiswal, Pranali Puradkar and Kunal Jhaveri
Funding Agency and Grant Number
Corresponding Author Kunal Jhaveri, MD, Department of Medical Affairs, Zydus Healthcare Limited, Zydus Tower, CTS 460/6, Village Pahadi Off IB Patel Road, Goregaon East, Mumbai 400063, Mahārāshtra, India. kunal.jhaveri@zyduslife.com
Key Words Gastroesophageal reflux disease; Heartburn; Acid reflux; Rabeprazole; Dual delayed-release
Core Tip The novel dual delayed-release formulation of rabeprazole, Happi ER, addresses the unmet needs of gastroesophageal reflux disease (GERD) management by offering both immediate and sustained acid suppression. This real-world evidence study demonstrated significant improvements in heartburn severity, reduced night-time awakenings, and enhanced patient satisfaction, particularly in patients with mild-to-moderate GERD. With a safety profile comparable to that of traditional proton pump inhibitors and superior efficacy in managing nocturnal symptoms, Happi ER provides a comprehensive and reliable solution for long-term GERD management.
Publish Date 2025-03-03 07:31
Citation <p>Lawate P, Chauhan V, Prasad LR, Pawar A, Puranik AG, Bansal A, Koganti A, Jaiswal A, Puradkar P, Jhaveri K. Real-world-evidence, prospective-observational study to evaluate safety and effectiveness of rabeprazole dual-delayed-release capsules in patients with gastroesophageal reflux disease. <i>World J Gastrointest Pharmacol Ther</i> 2025; 16(1): 103898</p>
URL https://www.wjgnet.com/2150-5349/full/v16/i1/103898.htm
DOI https://dx.doi.org/10.4292/wjgpt.v16.i1.103898
Full Article (PDF) WJGPT-16-103898-with-cover.pdf
STROBE Statement 103898-STROBE-statement.pdf
Manuscript File 103898_Auto_Edited_055300.docx
Answering Reviewers 103898-answering-reviewers.pdf
Audio Core Tip 103898-audio.mp4
Biostatistics Review Certificate 103898-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 103898-conflict-of-interest-statement.pdf
Copyright License Agreement 103898-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 103898-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 103898-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 103898-non-native-speakers.pdf
Peer-review Report 103898-peer-reviews.pdf
Scientific Misconduct Check 103898-scientific-misconduct-check.png
Scientific Editor Work List 103898-scientific-editor-work-list.pdf
CrossCheck Report 103898-crosscheck-report.pdf