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11/12/2025 9:52:44 AM | Browse: 11 | Download: 36
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Received |
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2024-12-16 10:24 |
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Peer-Review Started |
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2024-12-16 10:25 |
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To Make the First Decision |
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Return for Revision |
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2025-02-24 01:45 |
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Revised |
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2025-08-29 02:30 |
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Second Decision |
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2025-10-15 02:35 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-10-15 09:52 |
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Articles in Press |
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2025-10-15 09:52 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-11-06 09:39 |
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Publish the Manuscript Online |
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2025-11-12 09:50 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Editorial |
| Article Title |
Rethinking p16, p53, and HPV in HNCSCC through lessons from glioblastoma subclonal evolution toward patient-centric N-of-1 single-cell RNA sequencing paradigm
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Henry Michael Lee and Shengwen Calvin Li |
| Funding Agency and Grant Number |
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| Corresponding Author |
Shengwen Calvin Li, PhD, Department of Neurology, University of California-Irvine School of Medicine, 1001 Health Sciences Road, Orange, CA 92868, United States. sli@choc.org |
| Key Words |
p16; p53; Human papilloma virus; Head and neck cutaneous squamous cell carcinoma; Glioblastoma; Ultraviolet radiation; Subclonal evolution; Single-cell RNA sequencing; Spatial transcriptomics; N-of-1 paradigm |
| Core Tip |
Nam et al’s article provides a compelling investigation into the mysterious interaction between human papillomavirus, p16, and p53 in Asian populations. This investigation is part of the investigation into the pathogenesis and prognosis of cancer. The results of this study not only contribute to our expansion of knowledge regarding head and neck cutaneous squamous cell carcinoma, but they also question our preconceived assumptions regarding biomarkers that have traditionally been associated with positive outcomes. |
| Publish Date |
2025-11-12 09:50 |
| Citation |
<p>Lee HM, Li SC. Rethinking p16, p53, and HPV in HNCSCC through lessons from glioblastoma subclonal evolution toward patient-centric N-of-1 single-cell RNA sequencing paradigm. <i>World J Clin Cases</i> 2025; 13(32): 104208</p> |
| URL |
https://www.wjgnet.com/2307-8960/full/v13/i32/104208.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v13.i32.104208 |
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