Publication Name	World Journal of Gastroenterology
Manuscript ID	104579
Country	China

Received	2024-12-25 08:03
Peer-Review Started	2024-12-25 08:03
To Make the First Decision
Return for Revision	2025-03-08 05:06
Revised	2025-03-22 11:30
Second Decision	2025-04-18 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-04-18 05:58
Articles in Press	2025-04-18 05:58
Publication Fee Transferred	2025-03-27 14:20
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-04-24 06:32
Publish the Manuscript Online	2025-04-29 09:13

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Effect of sex on the outcomes of peroral endoscopic myotomy for the treatment of achalasia
Manuscript Source	Unsolicited Manuscript
All Author List	Chen-Yi Zhao, Ning Xu, Hao Dong, Ning-Li Chai and En-Qiang Linghu
Funding Agency and Grant Number
Corresponding Author	En-Qiang Linghu, Department of Digestive Diseases, Chinese PLA General Hospital, No. 28 Fuxing Road, Wanshoulu Street, Haidian District, Beijing 100853, China. linghuenqiang@vip.sina.com
Key Words	Sex difference; High-resolution esophageal manometry; Eckardt score; Peroral endoscopic myotomy; Achalasia
Core Tip	This is the first study that aimed to evaluate the impact of sex on achalasia symptoms, diagnostic findings, and postoperative improvement following peroral endoscopic myotomy (POEM). Our study drew a conclusion that sex may influence the severity and frequency of chest pain, with female cases exhibiting higher lower esophageal sphincter pressure and integrated relaxation pressure compared to male cases. POEM is proven to be a safe and effective procedure for both sexes, with female cases potentially experiencing greater benefits.
Publish Date	2025-04-29 09:13
Citation	<p>Zhao CY, Xu N, Dong H, Chai NL, Linghu EQ. Effect of sex on the outcomes of peroral endoscopic myotomy for the treatment of achalasia. <i>World J Gastroenterol</i> 2025; 31(17): 104579</p>
URL	https://www.wjgnet.com/1007-9327/full/v31/i17/104579.htm
DOI	https://dx.doi.org/10.3748/wjg.v31.i17.104579

Full Article (PDF)	WJG-31-104579-with-cover.pdf
Manuscript File	104579_Auto_Edited_070449.docx
Answering Reviewers	104579-answering-reviewers.pdf
Audio Core Tip	104579-audio.m4a
Biostatistics Review Certificate	104579-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	104579-conflict-of-interest-statement.pdf
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Signed Informed Consent Form(s) or Document(s)	104579-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	104579-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	104579-non-native-speakers.pdf
Peer-review Report	104579-peer-reviews.pdf
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Scientific Editor Work List	104579-scientific-editor-work-list.pdf
CrossCheck Report	104579-crosscheck-report.pdf